drugset / Trial / NCT05928455

The Immunogenicity and Safety Following a Heterologous Booster Dose of Recombinant SARS-CoV-2 Vaccine LYB001

NCT05928455

RandomizedParallel-groupOpen-labelPrevention

Summary

The goal of this clinical trial is to assess the immunogenicity and safety following a heterologous booster dose of recombinant SARS-CoV-2 vaccine (CHO cell) LYB001 in adults 18-59 years of age completed two- or three-dose inactivated COVID-19 vaccine. The main questions it aims to answer are: * whether LYB001 group is better on immunogenicity than the control group of inactivated vaccine? * whether LYB001 group has better performance on safety than the control group of inactivated vaccine, such as the lower adverse reaction rate?

Timeline

Start
2022-05-14
Primary completion
2022-10-10
Completion
2023-06-30

Drugs

EvaluationDrugModalityDoseRoute
Comparator CoronaVac Vaccine Intramuscular
Subject LYB001 Vaccine 30 ug Intramuscular
Subject LYB001 Vaccine 60 ug Intramuscular

Indications