Drugs / Gene-Corrected Macrophages
last change Sep 2026 re-read 3 minutes ago

Gene-Corrected Macrophages

Cell therapy targets CSF2RA via restoration

Developed for
hereditary pulmonary alveolar proteinosis
Investigated by
Children's Hospital Medical Center, Cincinnati · National Heart, Lung, and Blood Institute (NHLBI) · University of South Florida

Trials 1

202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/2 NCT05761899 Jun 2023 → Sep 2026 overdue hereditary pulmonary alveolar proteinosis Children's Hospital Medical Center, Cincinnati Recruiting No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as Gene-Corrected Macrophages ClinicalTrials.gov intervention name — accepted as the source's own label NCT05761899 ↗
Action Restore “uses a novel approach to restore AM function” NCT05761899 ↗
Modality Cell therapy “new type of cell transplantation therapy” NCT05761899 ↗
Route Other “by bronchoscopic instillation into individual lung segments” NCT05761899 ↗
Target CSF2RA “CSF2RA gene-corrected macrophages” NCT05761899 ↗