drugset / Trial / NCT05761899
Safety and Efficacy of PMT Therapy of hPAP
Phase 1/2
Recruiting
3 enrolled
Children's Hospital Medical Center, Cincinnati
National Heart, Lung, and Blood Institute (NHLBI) · collabUniversity of South Florida · collab
NaSingle-groupOpen-labelTreatment
Summary
The major goal of this study is to evaluate a new type of cell transplantation therapy for individuals with hereditary PAP, study a new treatment that may be useful for treatment of other diseases, and research mechanisms that drive the development and function of lung macrophages.
Timeline
- Start
- 2023-06-26
- Primary completion
- 2026-09-01
- Completion
- 2038-10-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Gene-Corrected Macrophages | Cell therapy | 11.1 cells/kg | Other |
| Subject | Gene-Corrected Macrophages | Cell therapy | 580000 cells | Other |
| Subject | Gene-Corrected Macrophages | Cell therapy | 7.78e+08 cells | Other |