Drugs / urea
Trials 19 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 1/22 trials | ||||||
| Phase 1/2 | NCT06366230 | Sep 2025 → Jun 2028 expected | dialysis disequilibrium syndrome, end stage renal failure, metabolic acidosis | University of California, San Francisco | Recruiting | No outcome recorded |
| Phase 1/2 | NCT07360639 | Jun → Dec 2025 | — | Universitas Syiah Kuala | Completed | No outcome recorded |
| Phase 26 trials | ||||||
| Phase 2 | NCT06391034 | Sep 2024 → Dec 2028 expected | prostate cancer | Robert Bok, MD, PhD | Recruiting | No outcome recorded |
| Phase 2 | NCT04588207 | Dec 2021 → Sep 2022 | inappropriate ADH syndrome | Helbert Rondon Berrios, MD, MS | Terminated | No outcome recorded |
| Phase 2 | NCT02249884 | Feb 2014 → Mar 2015 | radiodermatitis | University of Brasilia | Completed | No outcome recorded |
| Phase 2 | NCT03001466 | Jan 2014 → Jan 2016 | — | Assiut University | Completed | No outcome recorded |
| Phase 2 | NCT01934829 | Jul 2009 → Jul 2010 | hepatocellular carcinoma | Chinese Anti-Cancer Association | Completed | No outcome recorded |
| Phase 2 | NCT00667589 | Jun 2008 → Dec 2010 | exanthem, hand-foot syndrome | Northwestern University | Terminated | No outcome recorded |
| Phase 2/31 trial | ||||||
| Phase 2/3 | NCT05348278 | Dec 2021 → May 2023 | hand-foot syndrome | Mahidol University | Unknown | No outcome recorded |
| Phase 32 trials | ||||||
| Phase 3 | NCT02247830 | Jul 2015 → May 2017 | radiodermatitis | University of Brasilia | Completed | No outcome recorded |
| Phase 3 | NCT00576238 | Jan 2004 → Feb 2008 | atopic eczema | ACO Hud Nordic AB | Completed | No outcome recorded |
| Phase 42 trials | ||||||
| Phase 4 | NCT03212625 | Jan 2016 → Sep 2018 | hepatocellular carcinoma | Korea University Guro Hospital | Completed | No outcome recorded |
| Phase 4 | NCT00576550 | Oct 2007 → May 2008 | hand dermatosis | ACO Hud Nordic AB | Completed | No outcome recorded |
| Phase not applicable6 trials | ||||||
| — | NCT07033962 | Jun 2025 → Jun 2026 overdue | tinea unguium | Assiut University | Not yet recruiting | No outcome recorded |
| — | NCT07162454 | Nov 2024 → May 2025 | diabetic polyneuropathy | Universidad Complutense de Madrid | Completed | No outcome recorded |
| — | NCT04552873 | Dec 2020 → Dec 2024 overdue | inappropriate ADH syndrome, subarachnoid hemorrhage | University Hospital, Grenoble | Active not recruiting | No outcome recorded |
| — | NCT01754740 | Jan 2010 → Mar 2012 | burning mouth syndrome | University of Sao Paulo General Hospital | Completed | No outcome recorded |
| — | NCT00808366 | Oct 2008 → Jun 2009 | tinea unguium | Pierre Fabre Dermo Cosmetique | Unknown | No outcome recorded |
| — | NCT00005889 | Oct 1999 → ? | hyperglycemia | National Center for Research Resources (NCRR) | Unknown | No outcome recorded |
Also used as a comparator or background therapy in 9 trials
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 21 trial | ||||||
| Phase 2 | NCT05641246 Comparator | Dec 2022 → Nov 2023 | hand-foot syndrome | German University in Cairo | Completed | No outcome recorded |
| Phase 32 trials | ||||||
| Phase 3 | NCT07245238 Background | Nov 2025 → Dec 2027 expected | systemic sclerosis | Khon Kaen University | Recruiting | No outcome recorded |
| Phase 3 | NCT04127513 Comparator | Apr → May 2017 | — | Indonesia University | Completed | No outcome recorded |
| Phase 42 trials | ||||||
| Phase 4 | NCT02705664 Comparator | Jan → Sep 2016 | dermatomycosis | Galderma R&D | Completed | No outcome recorded |
| Phase 4 | NCT00771121 Comparator | — | atopic eczema | ACO Hud Nordic AB | Unknown | No outcome recorded |
| Phase not applicable4 trials | ||||||
| — | NCT07689435 Comparator | Jul 2026 → Jun 2027 expected | autosomal recessive congenital ichthyosis | Institute of Dermatology, Thailand | Not yet recruiting | No outcome recorded |
| — | NCT07012343 Background | Jan 2025 → Jun 2026 overdue | fungal infection of the toenail | Chulalongkorn University | Active not recruiting | No outcome recorded |
| — | NCT06583369 Comparator | Mar 2024 → Mar 2025 | hand-foot syndrome | Peking University Cancer Hospital & Institute | Unknown | No outcome recorded |
| — | NCT02191007 Comparator | Nov 2013 → May 2014 | psoriasis | Xijing Hospital | Completed | No outcome recorded |
Evidence & citations 5 cited values
Every value below carries the sentence it was read from. 28 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Urea | “Urea is used to treat dry/rough skin conditions (such as eczema, psoriasis, corns, callus) and some nail problems (such as ingrown nails).” NCT05641246 ↗26“this intervention was application of cream containing 10% urea as the standard method in treatment of xerosis cutis” NCT07360639 ↗ “received a topical cream containing cannabidiol and 10% urea” NCT07162454 ↗ “Initial treatment with bifonazole-urea ointment for 3 weeks.” NCT00808366 ↗ “Spread urea cream (urea 20%)” NCT03212625 ↗ |
| Known as | (CARBAMIDE) | “Standard of care Urea-based cream (CARBAMIDE®) will be applied to hands and feet 2-3 times daily for 14 days starting from the first dose and cycle of Capecitabine (XELODA ®).” NCT05641246 ↗ |
| Known as | Uréia | ClinicalTrials.gov intervention name — accepted as the source's own label NCT01754740 ↗ |
| Modality | Diagnostic / imaging agent | “metabolic MR imaging” NCT06391034 ↗ |
| Route | Intravenous | “[15N]urea IV beginning at -12 hours” NCT00005889 ↗ |