Drugs / 177Lu-DTPA-omburtamab

Trials 3

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT07698899 Jul 2026 → Jun 2030 expected medulloblastoma, metastatic malignant neoplasm in the brain Memorial Sloan Kettering Cancer Center Recruiting No outcome recorded
Phase 1/22 trials
Phase 1/2 NCT04315246 Aug 2022 → Dec 2024 neoplastic meningitis Y-mAbs Therapeutics Withdrawn No outcome recorded Stop: Business
Phase 1/2 NCT04167618 Sep 2021 → Aug 2022 childhood medulloblastoma Y-mAbs Therapeutics Terminated No outcome recorded Stop: Business

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as 177Lu-DTPA-omburtamab “Adults with leptomeningeal metastasis from solid tumors will be treated with 177Lu-DTPA-omburtamab, which is a radioactive labelling of a murine monoclonal antibody targeting B7-H3.” NCT04315246 ↗
2

“A Study of 177Lu-DTPA-Omburtamab in Children and Adolescents With Brain Cancer or Cancer That Has Spread to the Central Nervous System (CNS)” NCT07698899 ↗

NCT04167618 ↗

Known as Drug: 177Lu-DTPA-omburtamab “Drug: 177Lu-DTPA-omburtamab” NCT04315246 ↗
Modality Monoclonal antibody “which is a radioactive labelling of a murine monoclonal antibody targeting B7-H3” NCT04167618 ↗
Route Other “Intracerebroventricular administration of 177Lu-DTPA-omburtamab” NCT04167618 ↗