drugset / Trial / NCT04167618

177Lu-DTPA-Omburtamab Radioimmunotherapy for Recurrent or Refractory Medulloblastoma

NCT04167618 ↗

Phase 1/2 Terminated 2 enrolled Y-mAbs Therapeutics
NaSingle-groupOpen-labelTreatment

Summary

Children and adolescents diagnosed with medullablastoma and with recurrent or refractory to frontline therapy will be treated with 177Lu-DTPA-omburtamab, which is a radioactive labelling of a murine monoclonal antibody targeting B7-H3.

Timeline

Start
2021-09-30
Primary completion
2022-08-11
Completion
2022-08-11

Outcome

Outcome not reported

Stopped (Business): “Business priorities”

Drugs

EvaluationDrugModalityDoseRoute
Subject 177Lu-DTPA-omburtamab Monoclonal antibody — Other