Drugs / PF-03049423
last change Dec 2015 re-read 3 minutes ago

PF-03049423

Small molecule targets PDE5A via inhibition

Developed for
ischemic stroke
Investigated by
Pfizer

Trials 1

20112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 21 trial · 1 missed
Phase 2 NCT01208233 Dec 2010 → Dec 2013 ischemic stroke Pfizer Terminated Missed primary
Comparator or background therapy1 trial
Phase 1 NCT01161069 Comparator Aug → Dec 2009 — Pfizer Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as PF-03049423 ClinicalTrials.gov intervention name — accepted as the source's own label NCT01208233 ↗
1

NCT01161069 ↗

Action Inhibit “phosphodiesterase-5 inhibitor PF-03049423” PMID 26738812 ↗ Dec 2015
1

“Phosphodiesterase 5A inhibitor” CHEMBL591501 ↗

Modality Small molecule — CHEMBL591501 ↗
Route Oral “PF-03049423 in oral solution, 2.5 mg, given once daily for 14 days; healthy young adult volunteers” NCT01161069 ↗
Target PDE5A “Phosphodiesterase 5A inhibitor” CHEMBL591501 ↗