drugset / Trial / NCT01161069
A Study To Evaluate The Safety And Tolerability Of Different Doses Of PF-03049423 In Healthy Adult Volunteers And Healthy Older Volunteers
RandomizedParallel-groupDouble-blind
Summary
The purpose this study is to evaluate the safety and toleration of PF-03049423 following multiple dose administration as an oral solution to healthy young adult volunteers and healthy elderly volunteers. The study will also evaluate the pharmacokinetics of PF-03049423 after multiple dose administration to healthy young adult volunteers and healthy elderly volunteers. The study will also explore the relationship between blood pressure (supine and standing) and PF-03049423 concentration.
Timeline
- Start
- 2009-08
- Primary completion
- 2009-12
- Completion
- 2009-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | PF-03049423 | Small molecule | 2.5 mg | Oral |
| Comparator | PF-03049423 | Small molecule | 6 mg | Oral |
| Comparator | PF-03049423 | Small molecule | 7.5 mg | Oral |
| Comparator | PF-03049423 | Small molecule | 10 mg | Oral |
| Comparator | PF-03049423 | Small molecule | 12 mg | Oral |
Indications
No indication recorded.