Drugs / Ornidazole
last change Aug 2026 re-read 2 minutes ago

Ornidazole

Other / unclassified

Developed for
Clostridium difficile colitis · hepatic encephalopathy · irritable bowel syndrome · ulcerative colitis · acute graft versus host disease · acute pancreatitis · allergic rhinitis · autism spectrum disorder
+27 more · chronic kidney disease · Clostridium infectious disease · colon carcinoma · constipation disorder · Crohn disease · depressive disorder · graft versus host disease · heart failure · insomnia · intestinal dysmotility syndrome · lymphoma · NAFLD1 · necrotizing enterocolitis · pancreatic ductal adenocarcinoma · Parkinson disease · primary sclerosing cholangitis · protein-energy malnutrition · psoriatic arthritis · rectal cancer · rhinitis · schizophrenia · steroid-resistant nephrotic syndrome · type 2 diabetes mellitus · amyotrophic lateral sclerosis · anorexia nervosa · infectious peritonitis · obesity disorder
Investigated by
Assistance Publique - Hôpitaux de Paris · The Second Hospital of Nanjing Medical University · Air Force Military Medical University, China · Faming Zhang · First Affiliated Hospital Xi'an Jiaotong University · M.D. Anderson Cancer Center
+51 more · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) · Benoit Guery · CRB-HUEP · Changhai Hospital · Chinese Academy of Medical Sciences, Fuwai Hospital · Crohn's and Colitis Foundation · Daping Hospital and the Research Institute of Surgery of the Third Military Medical University · Eighth Affiliated Hospital, Sun Yat-sen University · First Hospital of Guangzhou · Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Fred Hutchinson Cancer Center · French National Institute of Health and Medical Research · Helsinki University Central Hospital · Icahn School of Medicine at Mount Sinai · Jinling Hospital, China · Leland Metheny · Lifespan · Maimónides Biomedical Research Institute of Córdoba · Manufacturer Vilhelm Pedersen Foundation · Massachusetts General Hospital · Medical University of Graz · Medical University of Warsaw · Memorial University of Newfoundland · Microbiome Health Research Institute · Mikrobiomik Healthcare Company S.L. · Montefiore Medical Center · Nanjing Medical University · National Heart, Lung, and Blood Institute (NHLBI) · National Institutes of Health (NIH) · Odense Patient Data Explorative Network · Odense University Hospital · Peking University People's Hospital · Rambam Health Care Campus · Region of Southern Denmark · Shanghai Asclepius Meditec Inc. · Shanghai Zhongshan Hospital · Stanford University · Tel-Aviv Sourasky Medical Center · The Danish Regions (Medicinpuljen) · The Danish Rheumatism Association · The First Affiliated Hospital of Air Force Medicial University · The First Affiliated Hospital of Guangzhou Medical University · The Psoriasis Association, Denmark · Third Military Medical University · Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · University Hospital, Clermont-Ferrand · University of Cape Town · University of Southern Denmark · Weill Medical College of Cornell University · Zhang Ting · Zhongshan Hospital Xiamen University

Trials 48 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 05 trials
Phase 0 NCT07683936 Jun 2026 → Jan 2027 expected hepatic encephalopathy Air Force Military Medical University, China Recruiting No outcome recorded
Phase 0 NCT07003438 Jun 2025 → Apr 2026 overdue steroid-resistant nephrotic syndrome Zhang Ting Not yet recruiting No outcome recorded
Phase 0 NCT05598112 Apr 2023 → Dec 2026 expected Chinese Academy of Medical Sciences, Fuwai Hospital Recruiting No outcome recorded
Phase 0 NCT04975217 Dec 2021 → Dec 2026 pancreatic ductal adenocarcinoma M.D. Anderson Cancer Center Suspended No outcome recorded
Phase 0 NCT02733744 May → Dec 2016 Massachusetts General Hospital Completed No outcome recorded
Phase 18 trials
Phase 1 NCT05067595 Jan 2025 → Dec 2027 expected graft versus host disease Fred Hutchinson Cancer Center Recruiting No outcome recorded
Phase 1 NCT05911997 Jan 2024 → Jul 2026 overdue Clostridium difficile colitis Icahn School of Medicine at Mount Sinai Recruiting No outcome recorded
Phase 1 NCT06030752 Sep 2023 → Apr 2027 expected autism spectrum disorder The Second Hospital of Nanjing Medical University Recruiting No outcome recorded
Phase 1 NCT03747718 Dec 2022 → Dec 2024 Crohn disease Stanford University Withdrawn No outcome recorded
Phase 1 NCT06368895 Apr 2021 → Jun 2025 hepatic encephalopathy, immune dysregulation, neurodevelopmental defects, and colitis Fondazione Policlinico Universitario Agostino Gemelli IRCCS Unknown No outcome recorded
Phase 1 NCT03087097 Apr 2019 → Jul 2020 protein-energy malnutrition Microbiome Health Research Institute Terminated No outcome recorded
Phase 1 NCT02469272 May 2015 → Jun 2018 NAFLD1 Lifespan Unknown No outcome recorded
Phase 1 NCT02399618 Mar 2015 → Sep 2016 Clostridium infectious disease Jinling Hospital, China Unknown No outcome recorded
Phase 1/23 trials
Phase 1/2 NCT07628777 Jun 2026 → Mar 2027 expected heart failure The First Affiliated Hospital of Air Force Medicial University Not yet recruiting No outcome recorded
Phase 1/2 NCT07454408 Mar 2026 → Jun 2028 expected hepatic encephalopathy Air Force Military Medical University, China Not yet recruiting No outcome recorded
Phase 1/2 NCT03167398 Feb 2018 → Dec 2019 Rambam Health Care Campus Completed No outcome recorded
Phase 26 trials
Phase 2 NCT07477782 May 2026 → Apr 2029 expected inflammatory bowel disease, primary sclerosing cholangitis Assistance Publique - Hôpitaux de Paris Not yet recruiting No outcome recorded
Phase 2 NCT06218602 Feb 2024 → Aug 2026 overdue lymphoma M.D. Anderson Cancer Center Recruiting No outcome recorded
Phase 2 NCT04059757 May 2022 → Jun 2023 acute graft versus host disease Leland Metheny Withdrawn No outcome recorded
Phase 2 NCT04760665 Oct 2021 → Nov 2023 Maimónides Biomedical Research Institute of Córdoba Terminated No outcome recorded
Phase 2 NCT03998488 Jan 2020 → Jun 2023 ulcerative colitis Weill Medical College of Cornell University Completed No outcome recorded
Phase 2 NCT02328547 May 2015 → Oct 2017 irritable bowel syndrome Montefiore Medical Center Completed No outcome recorded
Phase 2/31 trial
Phase 2/3 NCT06603883 Oct 2024 → Mar 2026 intestinal dysmotility syndrome Union Hospital, Tongji Medical College, Huazhong University of Science and Technology Completed No outcome recorded
Phase 39 trials
Phase 3 NCT07458984 Apr 2026 → Dec 2029 expected Clostridium difficile colitis Helsinki University Central Hospital Recruiting No outcome recorded
Phase 3 NCT06433180 Jul 2025 → Jul 2028 expected irritable bowel syndrome Assistance Publique - Hôpitaux de Paris Not yet recruiting No outcome recorded
Phase 3 NCT05266807 Mar 2023 → Apr 2027 expected Clostridium difficile colitis Benoit Guery Recruiting No outcome recorded
Phase 3 NCT02801656 Dec 2020 → Sep 2022 Clostridium difficile colitis Memorial University of Newfoundland Withdrawn No outcome recorded
Phase 3 NCT03483246 Sep 2018 → Sep 2025 overdue ulcerative colitis Assistance Publique - Hôpitaux de Paris Active not recruiting No outcome recorded
Phase 3 NCT03491540 Sep 2018 → Oct 2023 rectal cancer Assistance Publique - Hôpitaux de Paris Completed No outcome recorded
Phase 3 NCT03475680 Aug 2018 → Aug 2021 colon carcinoma Assistance Publique - Hôpitaux de Paris Terminated No outcome recorded
Phase 3 NCT03819803 Mar 2017 → Mar 2026 overdue acute graft versus host disease Medical University of Graz Recruiting No outcome recorded
Phase 3 NCT02618720 May 2016 → Nov 2019 University Hospital, Clermont-Ferrand Completed No outcome recorded
Phase 41 trial
Phase 4 NCT02998112 Dec 2016 → Jul 2017 ulcerative colitis The Second Hospital of Nanjing Medical University Unknown No outcome recorded
Phase not applicable15 trials
NCT07599046 Apr 2026 → Jan 2027 expected type 2 diabetes mellitus Eighth Affiliated Hospital, Sun Yat-sen University Not yet recruiting No outcome recorded
NCT07464392 Apr 2026 → Jul 2027 expected acute pancreatitis Changhai Hospital Recruiting No outcome recorded
NCT06388863 Feb 2025 → Dec 2026 expected Parkinson disease Shanghai Zhongshan Hospital Recruiting No outcome recorded
NCT06475430 Jan 2025 → Jun 2026 overdue Peking University People's Hospital Not yet recruiting No outcome recorded
NCT06372184 Jun 2024 → Jun 2029 expected allergic rhinitis The Second Hospital of Nanjing Medical University Not yet recruiting No outcome recorded
NCT06437041 Jun 2024 → Dec 2029 expected irritable bowel syndrome Faming Zhang Not yet recruiting No outcome recorded
NCT06427863 Jun 2024 → Dec 2029 expected constipation disorder Faming Zhang Not yet recruiting No outcome recorded
NCT06350448 May 2024 → May 2029 expected rhinitis The Second Hospital of Nanjing Medical University Not yet recruiting No outcome recorded
NCT06333405 May 2024 → Jan 2025 necrotizing enterocolitis Medical University of Warsaw Unknown No outcome recorded
NCT05850572 Jul 2023 → Dec 2025 overdue depressive disorder First Affiliated Hospital Xi'an Jiaotong University Not yet recruiting No outcome recorded
Also used as a comparator or background therapy in 9 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 01 trial
Phase 0 NCT04968951 Comparator Nov 2021 → Aug 2022 ulcerative colitis Ari M Grinspan Terminated No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT02741518 Comparator Apr 2017 → Oct 2018 obesity disorder Brigham and Women's Hospital Completed No outcome recorded
Phase 24 trials
Phase 2 NCT05204641 Comparator Jan 2022 → Oct 2024 Parkinson disease Medical University of Warsaw Completed No outcome recorded
Phase 2 NCT02346669 Comparator Apr 2016 → Jan 2018 obesity disorder, type 2 diabetes mellitus Tel-Aviv Sourasky Medical Center Unknown No outcome recorded
Phase 2 NCT02557685 Comparator Jun 2015 → Mar 2016 Clostridium difficile colitis The Miriam Hospital Unknown No outcome recorded
Phase 2 NCT01703494 Comparator Oct 2012 → May 2015 Clostridium difficile colitis Colleen Kelly Unknown No outcome recorded
Phase 41 trial
Phase 4 NCT06828874 Comparator May 2023 → Sep 2024 infectious peritonitis Yangtze River Pharmaceutical Group Jiangsu Zilong Pharmaceutical Co. Ltd Completed No outcome recorded
Phase not applicable2 trials
NCT06744751 Comparator Sep 2025 → Dec 2026 expected anorexia nervosa Shanghai Mental Health Center Not yet recruiting No outcome recorded
NCT03766321 Comparator Jul 2020 → Oct 2024 overdue amyotrophic lateral sclerosis University Hospital of Modena Active not recruiting No outcome recorded

Evidence & citations 16 cited values

Every value below carries the sentence it was read from. 61 sources stand behind the page.

FieldValueCited text
Known as ornidazole ClinicalTrials.gov intervention name — accepted as the source's own label NCT02618720
5

NCT06427863

NCT06828874

NCT03491540

NCT03475680

NCT06437041

Known as faecal microbiota transplantation Faecal microbiota transplantation (FMT) could be an effective and safe strategy to decolonise intestinal carriers of KPC-producing Klebsiella pneumoniae (KPC-Kp)” PMID 35387830 Apr 2022
Known as Fecal Microbiota Transplantation “Effect of Fecal Microbiota Transplantation on Aging and the Underlying Mechanism of Gut Microbiome Restoration: a Randomized Clinical Trial” NCT05598112
45

“Participants will be treated with healthy donor-derived fecal microbiota transplantation in the form of oral capsules.” NCT06388863

“Objective: To investigate whether Fecal Microbiota Transplantation(FMT) can improve sleep in patients with insomnia” NCT05427331

NCT03998488

NCT04975217

NCT03058900

NCT07003438

NCT05838118

NCT06433180

NCT05266807

NCT04760665

NCT07599046

NCT06603883

NCT03087097

NCT03483246

NCT05067595

NCT05850585

NCT04059757

NCT02733744

NCT05850572

NCT06475430

NCT02469272

NCT06218602

NCT06744751

NCT03167398

NCT03766321

NCT07477782

NCT06333405

NCT02328547

NCT07464392

NCT05911997

NCT02998112

NCT02557685

NCT03819803

NCT02801656

NCT04861649

NCT01703494

NCT07628777

NCT02741518

NCT07683936

NCT02399618

NCT02346669

NCT04968951

NCT06368895

NCT03747718

NCT07454408

Known as FMT “A randomised, placebo-controlled trial of faecal microbiota transplantation (FMT) infused into the small intestine of patients with PsA with active peripheral disease who are...” PMID 29703851 Apr 2018
21

“The process of fecal microbiota transplantation FMT, where fecal microbial community from a healthy individual is transferred into a recipient, has been established as an...” NCT03747718

“Fecal microbiota transplantation (FMT) is a novel, safe, convenient therapeutic treatment which transplant gut microbiota from donor to patient to rebuild a gut microecology.” NCT05838118

“Fecal microbiota transplantation (FMT), given as oral capsules, compared with placebo for the treatment of refractory diarrhea-predominant irritable bowel syndrome (IBS-D)” NCT02328547

“Fecal Microbiota Transplantation (FMT) is the transfer of fecal material from a healthy donor to a patient in order to restore the diversity of the intestinal microbiota.” NCT04059757

“Fecal microbiota transplant (FMT) is an effective therapy for recurrent Clostridioides difficile infection (rCDI) but has undefined composition and poor scalability.” PMID 42230754 Jun 2026

“Fecal microbiota transplantation (FMT), in which fecal material enriched with commensal microorganisms is transferred from a healthy donor” NCT03167398

“The clinical trial aims to evaluate the efficacy of fecal microbiota transplantation (FMT) after standard of care treatment” NCT05266807

“Objective: To investigate whether Fecal Microbiota Transplantation(FMT) can improve sleep in patients with insomnia” NCT05427331

“Fecal Microbiota Transplantation (FMT) involves transplanting healthy intestinal flora into a patient's gut.” NCT06744751

“treatment with fecal microbiota transplantation (FMT) is effective at treating gut-related side effects” NCT06218602

“fecal microbiota transplantation (FMT) using oral capsules containing frozen stools” NCT06433180

“Patients will receive four fecal microbiota transplantation (FMT) capsules.” NCT04760665

“Fecal microbiota transplantation (FMT) by nasal jejunal tube” NCT06603883

“Fecal Microbiota Transplantation (FMT) Capsules” NCT07628777

“Fecal Microbiota Transplantation (FMT)” NCT03483246

“fecal microbiota transplantation (FMT)” NCT02998112

“Fecal Microbiota Transplantation (FMT)” NCT02733744

“Fecal microbiota transplantation (FMT)” NCT07599046

“Fecal microbiota transplantation (FMT)” NCT07477782

“Fecal microbiota transplantation(FMT)” NCT05850585

“Fecal microbiota transplantation(FMT)” NCT05850572

Known as FMT, stool transplant FMT, stool transplantNCT02557685
Known as Healthy donor stool ClinicalTrials.gov intervention name — accepted as the source's own label NCT07458984
Known as Mbiotix “The patients were randomly assigned to receive either fecal microbiota (Mbiotix, Human Biome Institute) or placebo (auto-fecal microbiota, prepared from the patient's stool) in...” PMID 41674471 Feb 2026
Known as MBiotix HBI “Fecal Microbiota as a suspension obtained from healthy unrelated donor (woman in 3rd trimester of pregnancy) introduced two times per treatment: * as a deep rectal infusion,...” NCT06333405
Known as NSC-95075 ChEMBL registry synonym — accepted as the source's own label CHEMBL1449676
Known as Ornidazol ChEMBL registry synonym — accepted as the source's own label CHEMBL1449676
Known as RO 7-0207 ChEMBL registry synonym — accepted as the source's own label CHEMBL1449676
Known as Tiberal ChEMBL registry synonym — accepted as the source's own label CHEMBL1449676
Known as Washed Microbiota Transplantation ClinicalTrials.gov intervention name — accepted as the source's own label NCT06030752
2

NCT06372184

NCT06350448

Action Restore “to restore missing components of normal intestinal flora” NCT01703494
Modality Other / unclassified “Fecal microbiota transplant from healthy, unrelated donor via freeze-dried capsule” NCT02399618
Route Other “delivered via colonoscopy” NCT01703494