drugset / Trial / NCT05850572
A Study of the Efficacy of Fecal Microbiota Transplantation(FMT) in the Treatment of Depression
RandomizedParallel-groupDouble-blindTreatment
Summary
Patients with depression were enrolled and randomly divided into two groups, namely FMT combined with antidepressant group and Antidepressant alone group.The former received FMT capsules and antidepressants, and the latter received oral placebo and antidepressants for an 8-week intervention.Before and after intervention, venous blood samples were collected from patients for routine tests such as liver and kidney function to judge the safety of treatment. At the same time, psychological scales were used to evaluate the improvement of patients' depressive symptoms, so as to judge the efficacy and safety of FMT combined with antidepressants.
Timeline
- Start
- 2023-07
- Primary completion
- 2025-12
- Completion
- 2026-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Ornidazole | Other / unclassified | 1e+12 unknown | — |