drugset / Trial / NCT00000894
Comparison of Two Drugs, Cidofovir and Ganciclovir, in Treating Patients With AIDS Who Have CMV Retinitis
Parallel-groupTreatment
Summary
To compare cidofovir with a commonly used treatment regimen, ganciclovir given by mouth (oral) and through an eye device (intraocular) , in order to determine the safety and effectiveness of cidofovir in preventing vision loss in patients who have AIDS complicated by CMV (cytomegalovirus) retinitis. Cidofovir needs to be compared to ganciclovir to determine the best way to treat CMV retinitis.
Timeline
- Start
- —
- Primary completion
- 2000-06
- Completion
- —
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | CIDOFOVIR ANHYDROUS | Small molecule | — | Intravenous |
| Subject | Ganciclovir | Small molecule | — | Oral |
| Background | Probenecid | Small molecule | — | Oral |