drugset / Trial / NCT00000950
Metabolism of Antituberculosis Drugs in HIV-Infected Persons With Tuberculosis
Treatment
Summary
The purpose of this study is to determine if a relationship exists between the level of antituberculosis drugs (isoniazid, rifampin, ethambutol, and pyrazinamide) in the blood and the outcome of HIV-positive patients with tuberculosis. This study also evaluates how these drugs are absorbed and metabolized in the body.
Timeline
- Start
- —
- Primary completion
- 2002-05
- Completion
- —
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Ethambutol | Small molecule | — | — |
| Subject | Isoniazid | Small molecule | — | — |
| Subject | Pyrazinamide | Small molecule | — | — |
| Subject | Rifampicin | Small molecule | — | — |
| Background | Pyridoxine | Unknown | — | — |