Isoniazid

also known as INH · Generic name: Isoniazid. · Isoniazid (H) · Isoniazid I INH · isoniazid tablets · isonicotinic acid hydrazine · Rifinah · RIMIFON

Small molecule

Developed for: tuberculosis · HIV infectious disease · pulmonary tuberculosis · latent tuberculosis infection · multidrug-resistant tuberculosis · meningeal tuberculosis · anterior uveitis · drug-resistant tuberculosis
+11 more
· female genital tuberculosis · infectious disease with sepsis · lymph node tuberculosis · ocular tuberculosis · protein-energy malnutrition · respiratory tract infectious disorder · silicotuberculosis · tuberculosis, spinal · ulcer of lower limbs · X-linked erythropoietic protoporphyria · rifampicin-resistant tuberculosis
Investigated by: National Institute of Allergy and Infectious Diseases (NIAID) · Johns Hopkins University · Centers for Disease Control and Prevention · Huashan Hospital · National Taiwan University Hospital · University of Cape Town
+245 more
· Makerere University · The Aurum Institute NPC · Tuberculosis Research Centre, India · United States Agency for International Development (USAID) · University of Stellenbosch · Beijing Chest Hospital · European and Developing Countries Clinical Trials Partnership (EDCTP) · London School of Hygiene and Tropical Medicine · Medical Research Council · Sanofi · University College, London · University of California, San Francisco · University of Washington · ANRS, Emerging Infectious Diseases · Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections · All India Institute of Medical Sciences · Aurum Institute · Bill and Melinda Gates Foundation · Centre for the AIDS Programme of Research in South Africa · Chang Gung Memorial Hospital · Chengdu Public Health Clinical Center · Federal University of Mato Grosso · Global Alliance for TB Drug Development · Institute of Tropical Medicine, Belgium · Kaohsiung Veterans General Hospital. · Kenya Medical Research Institute · Merck Sharp & Dohme LLC · Michael Hoelscher · National Institute of Public Health, Mexico · National Institutes of Health Clinical Center (CC) · PENTA Foundation · Radboud University Medical Center · Shanghai Pulmonary Hospital, Shanghai, China · Sociedad Andaluza de Enfermedades Infecciosas · Taipei Veterans General Hospital, Taiwan · US Department of Veterans Affairs · University of Oxford · Wellcome Trust · West China Hospital · Aarhus University Hospital · Affiliated Wenling Hospital of Wenzhou Medical University · All India Institute of Medical Sciences, Bhubaneswar · All India Institute of Medical Sciences, Jodhpur · Anhui Chest Hospital · Asan Medical Center · Asian Medical Center · Assistance Publique - Hôpitaux de Paris · Barcelona Institute for Global Health · Bayer Healthcare Pharmaceuticals, Inc./Bayer Schering Pharma · Beijing Ditan Hospital · Beijing Municipal Science & Technology Commission · Beijing Research Institute for Tuberculosis Control · Beijing YouAn Hospital · Bhumibol Adulyadej Hospital · Biomedical Research and Training Institute, Zimbabwe · Boston Medical Center · Boston University · Botswana Ministry of Health · Buddhachinaraj Hospital · Centers for Disease Control, Taiwan · Centre Hospitalier Cocody · Centre for Tuberculosis Control of Guangdong Province · Changchun Infectious Disease Hospital · Chest Hospital of Guangxi Zhuang Autonomous Region · Chest of Hospital of Xinjiang Uygur Autonomous Region of the PRC · Chiangrai Prachanukroh Hospital · Chongqing Infectious Disease Medical Center · Chongqing Public Health Medical Center · Chris Hani Baragwanath Academic Hospital · Christian Medical College, Vellore, India · Columbia University · Communicable Disease Program, Brazil · Comprehensive International Program of Research on AIDS · Consortium to Respond Effectively to the AIDS/Tuberculosis Epidemic · all 251 on the full record

Regulatory milestones approvals, filings & regulatory actions · 1 recorded

Milestone	Jurisdiction	Brand	Indication	Date	Sentence it was read from
Approved	US (FDA)	NYDRAZID	—	1952-09-29	fda.gov ↗

Trials 120 · started per year

today

US approved 1952

19511952195319541955195619571958195919601961196219631964196519661967196819691970197119721973197419751976197719781979198019811982198319841985198619871988198919901991199219931994199519961997199819992000200120022003200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027202820292030

Phase	Registry id	Dates	Indication	Sponsor	Status	Outcome
Phase 111 trials
Phase 1	NCT07069582	Apr → Oct 2026 expected	tuberculosis	McGill University Health Centre/Research Institute of the McGill University Health Centre	Not yet recruiting	No outcome recorded
Phase 1	NCT07708779	Dec 2025 → Jul 2026 overdue	tuberculosis	University Medical Center Groningen	Recruiting	No outcome recorded
Phase 1	NCT05413551	Mar 2023 → Apr 2025	isoniazid toxicity, tuberculosis	Stanford University	Completed	No outcome recorded
Phase 1	NCT03886701	Apr → May 2019	HIV infectious disease, isoniazid toxicity, latent tuberculosis infection	Walter K. Kraft	Completed	No outcome recorded
Phase 1	NCT03510468	Jun 2018 → Nov 2022	—	National Institutes of Health Clinical Center (CC)	Completed	No outcome recorded
Phase 1	NCT02771249	Jun 2016 → Aug 2021	latent tuberculosis infection	National Institutes of Health Clinical Center (CC)	Completed	No outcome recorded
Phase 1	NCT02236078	Nov 2015 → Sep 2020	drug-resistant tuberculosis	Centers for Disease Control and Prevention	Completed	No outcome recorded
Phase 1	NCT02457208	Jul 2015 → Jan 2018	tuberculosis	University of Oxford	Completed	No outcome recorded
Phase 1	NCT01119521	Oct 2010 → Jul 2013	tuberculosis	National Institute of Allergy and Infectious Diseases (NIAID)	Completed	No outcome recorded
Phase 1	NCT00816426	Dec 2008 → Aug 2014	tuberculosis	National Institute of Allergy and Infectious Diseases (NIAID)	Completed	No outcome recorded
Phase 1	NCT00000778	—	HIV infectious disease, pulmonary tuberculosis	National Institute of Allergy and Infectious Diseases (NIAID)	Completed	No outcome recorded

Phase 1/26 trials
Phase 1/2	NCT05122026	Jan 2024 → Oct 2025 overdue	pregnancy disorder, tuberculosis	The Aurum Institute NPC	Active not recruiting	No outcome recorded
Phase 1/2	NCT05122767	May 2023 → Jul 2025 overdue	HIV infectious disease, tuberculosis	The Aurum Institute NPC	Active not recruiting	No outcome recorded
Phase 1/2	NCT04044001	Nov 2019 → Mar 2022	pulmonary tuberculosis	Michael Hoelscher	Completed	No outcome recorded
Phase 1/2	NCT03730181	Oct 2019 → Dec 2024	latent tuberculosis infection	Centers for Disease Control and Prevention	Completed	No outcome recorded
Phase 1/2	NCT03435146	Jan 2018 → Dec 2022	HIV infectious disease, respiratory tract infectious disorder	The Aurum Institute NPC	Completed	No outcome recorded
Phase 1/2	NCT02651259	Mar 2017 → Apr 2019	tuberculosis	National Institute of Allergy and Infectious Diseases (NIAID)	Completed	No outcome recorded
Phase 214 trials · 1 met primary · 2 missed
Phase 2	NCT07129629	Aug 2025 → Dec 2026 expected	pulmonary tuberculosis	Shanghai Pulmonary Hospital, Shanghai, China	Not yet recruiting	No outcome recorded
Phase 2	NCT05383742	Dec 2023 → Apr 2028 expected	meningeal tuberculosis	National Institute of Allergy and Infectious Diseases (NIAID)	Recruiting	No outcome recorded
Phase 2	NCT06041919	Sep 2023 → Jul 2024	pulmonary tuberculosis	Thirty Respiratory Limited	Terminated	No outcome recorded
Phase 2	NCT05971602	Jul 2023 → Feb 2025	pulmonary tuberculosis	Gates Medical Research Institute	Terminated	No outcome recorded
Phase 2	NCT05807399	Apr 2023 → Oct 2027 expected	pulmonary tuberculosis	Michael Hoelscher	Recruiting	No outcome recorded
Phase 2	NCT05124678	Dec 2021 → Mar 2022	tuberculosis	Makerere University	Unknown	No outcome recorded
Phase 2	NCT04311502	Nov 2021 → Jun 2024	HIV infectious disease, tuberculosis	National Institute of Allergy and Infectious Diseases (NIAID)	Terminated	Missed primary Stop: Enrollment
Phase 2	NCT05005637	Aug 2021 → Oct 2024	ocular tuberculosis	Faculty of Medicine, University of Indonesia	Completed	Met primary
Phase 2	NCT04272242	Feb → Dec 2021	HIV infectious disease, latent tuberculosis infection	National Institute of Allergy and Infectious Diseases (NIAID)	Terminated	No outcome recorded
Phase 2	NCT02821832	Jun 2017 → Oct 2021	pulmonary tuberculosis	National Institute of Allergy and Infectious Diseases (NIAID)	Completed	No outcome recorded
Phase 2	NCT02613169	Aug 2016 → Oct 2019	tuberculosis	University of Washington	Completed	Missed primary
Phase 2	NCT02371681	Feb 2015 → Sep 2017	pulmonary tuberculosis	National Institute of Allergy and Infectious Diseases (NIAID)	Completed	No outcome recorded
Phase 2	NCT01936831	Aug 2014 → Sep 2021	tuberculosis	Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections	Completed	No outcome recorded
Phase 2	NCT04802928	Apr → Sep 2008	ulcer of lower limbs	Pharma 2100	Withdrawn	No outcome recorded

Phase 2/38 trials · 1 met primary · 2 missed
Phase 2/3	NCT06568484	May 2026 → Jul 2027 expected	latent tuberculosis infection	Johns Hopkins University	Recruiting	No outcome recorded
Phase 2/3	NCT05401071	Jan 2023 → Oct 2024 overdue	pulmonary tuberculosis	Huashan Hospital	Recruiting	No outcome recorded
Phase 2/3	NCT03915366	Mar 2020 → Jan 2025	HIV infectious disease, cytomegalovirus infection, pneumonia, tuberculosis	Hospital Universitario 12 de Octubre	Completed	Missed primary
Phase 2/3	NCT02735590	Sep 2016 → Dec 2019	tuberculosis	University of Cape Town	Unknown	Mixed
Phase 2/3	NCT02454205	Nov 2015 → Dec 2020	extensively drug-resistant tuberculosis, multidrug-resistant tuberculosis	University of Cape Town	Completed	Met primary
Phase 2/3	NCT00080119	Feb 2004 → May 2009	HIV infectious disease, Pneumocystis infectious disease, tuberculosis	International Maternal Pediatric Adolescent AIDS Clinical Trials Group	Terminated	Missed primary
Phase 2/3	NCT00513396	Jan 2004 → Dec 2006	multidrug-resistant tuberculosis	GSVM Medical College	Completed	No outcome recorded
Phase 2/3	NCT00023348	Jul 1999 → Nov 2002	HIV infectious disease, tuberculosis	Centers for Disease Control and Prevention	Completed	No outcome recorded
Phase 335 trials · 6 met primary · 5 missed
Phase 3	NCT07332325	Oct 2026 → Mar 2029 expected	infectious disease with sepsis, tuberculosis	University of Virginia	Not yet recruiting	No outcome recorded
Phase 3	NCT07163143	Nov 2025 → Nov 2028 expected	tuberculosis	University College, London	Not yet recruiting	No outcome recorded
Phase 3	NCT06253715	Jan 2025 → Sep 2027 expected	lymph node tuberculosis, pulmonary tuberculosis	Johns Hopkins University	Recruiting	No outcome recorded
Phase 3	NCT06191692	Nov 2024 → Dec 2025	latent tuberculosis infection	Freundeskreis Für Internationale Tuberkulosehilfe e.V	Withdrawn	No outcome recorded
Phase 3	NCT05330884	Jul 2024 → Jun 2027	tuberculosis	Tuberculosis Research Centre, India	Suspended	No outcome recorded
Phase 3	NCT05994742	Jul 2024 → Aug 2026 overdue	HIV infectious disease, protein-energy malnutrition	Queen Mary University of London	Active not recruiting	No outcome recorded
Phase 3	NCT05917340	Mar 2024 → Sep 2027 expected	meningeal tuberculosis	Indian Council of Medical Research	Not yet recruiting	No outcome recorded
Phase 3	NCT06727864	Jan 2024 → Dec 2027 expected	pulmonary tuberculosis	Kaohsiung Veterans General Hospital.	Recruiting	No outcome recorded
Phase 3	NCT05454345	Oct 2022 → Jun 2025	pulmonary tuberculosis	First Affiliated Hospital of Zhejiang University	Unknown	No outcome recorded
Phase 3	NCT04600167	Jun 2022 → Dec 2025	diabetes mellitus, tuberculosis	Dr. Nyanda Elias Ntinginya	Unknown	No outcome recorded
Phase 3	NCT04738812	Apr 2022 → Nov 2025	HIV infectious disease, immunodeficiency disease, tuberculosis	ANRS, Emerging Infectious Diseases	Completed	No outcome recorded
Phase 3	NCT04528277	Sep 2020 → Sep 2021	female genital tuberculosis, female infertility, latent tuberculosis infection	Huashan Hospital	Unknown	No outcome recorded
Phase 3	NCT04856644	Jan 2020 → Dec 2023 overdue	pulmonary tuberculosis	Kaohsiung Veterans General Hospital.	Active not recruiting	No outcome recorded
Phase 3	NCT04117698	Nov 2019 → May 2023	anterior uveitis	Assistance Publique - Hôpitaux de Paris	Unknown	No outcome recorded
Phase 3	NCT03862248	Sep 2019 → Oct 2022	pulmonary tuberculosis	Institute of Tropical Medicine, Belgium	Withdrawn	No outcome recorded
Phase 3	NCT04094012	Sep 2019 → Oct 2023	latent tuberculosis infection	National Taiwan University Hospital	Completed	No outcome recorded
Phase 3	NCT03785106	Aug 2019 → Mar 2038 expected	—	The HIV Netherlands Australia Thailand Research Collaboration	Active not recruiting	No outcome recorded
Phase 3	NCT03568383	Jun 2019 → Jan 2027 expected	multidrug-resistant tuberculosis	National Institute of Allergy and Infectious Diseases (NIAID)	Active not recruiting	No outcome recorded
Phase 3	NCT02409290	Mar 2016 → May 2022	multidrug-resistant tuberculosis	IUATLD, Inc	Completed	Met primary
Phase 3	NCT02430259	Mar 2015 → Jun 2018	silicosis, tuberculosis	Huashan Hospital	Completed	Missed primary
Phase 3	NCT02120638	Apr 2014 → Apr 2016	multidrug-resistant tuberculosis	Huashan Hospital	Unknown	No outcome recorded
Phase 3	NCT01825031	Jun 2013 → Mar 2016	HIV infectious disease	Medical Research Council	Completed	Missed primary
Phase 3	NCT01582711	Sep 2012 → Oct 2014	latent tuberculosis infection	Centers for Disease Control and Prevention	Completed	Met primary
Phase 3	NCT01404312	May 2012 → Nov 2017	HIV infectious disease, tuberculosis	National Institute of Allergy and Infectious Diseases (NIAID)	Completed	Met primary
Phase 3	NCT01398618	May 2011 → Dec 2013	latent tuberculosis infection	National Taiwan University Hospital	Unknown	No outcome recorded
Phase 3	NCT01154959	Feb 2010 → Dec 2015	pulmonary tuberculosis	Tuberculosis Research Centre, India	Completed	No outcome recorded
Phase 3	NCT00495651	Mar 2008 → Jan 2015	HIV infectious disease, tuberculosis	French National Agency for Research on AIDS and Viral Hepatitis	Completed	Met primary
Phase 3	NCT00767975	Jan 2008 → Nov 2010	tuberculosis	National Taiwan University Hospital	Completed	Met primary
Phase 3	NCT00864383	Jan 2008 → Oct 2013	pulmonary tuberculosis	Global Alliance for TB Drug Development	Completed	Missed primary
Phase 3	NCT00317330	Dec 2004 → Jun 2005	tuberculosis	National Institute of Allergy and Infectious Diseases (NIAID)	Completed	No outcome recorded
Phase 3	NCT00330304	Jan 2003 → Nov 2011	tuberculosis	University of Cape Town	Completed	Met primary
Phase 3	NCT00130247	Apr 2002 → Sep 2008	tuberculosis	National Institute of Allergy and Infectious Diseases (NIAID)	Completed	Missed primary
Phase 3	NCT00351702	Feb 2001 → Sep 2008	HIV infectious disease, tuberculosis	Tuberculosis Research Centre, India	Completed	No outcome recorded
Phase 3	NCT00376012	Feb 2001 → Sep 2007	HIV infectious disease, tuberculosis	Tuberculosis Research Centre, India	Unknown	Missed primary
Phase 3	NCT00023335	Apr 1995 → Mar 2001	pulmonary tuberculosis	Centers for Disease Control and Prevention	Completed	No outcome recorded

Phase 427 trials · 2 met primary · 5 missed
Phase 4	NCT06153069	Nov 2025 → Nov 2027 expected	tuberculosis	Huashan Hospital	Recruiting	No outcome recorded
Phase 4	NCT05118490	Jul 2023 → Jul 2025 overdue	AIDS-related disorder, tuberculosis	The Aurum Institute NPC	Active not recruiting	No outcome recorded
Phase 4	NCT05411744	Jul 2022 → Jan 2026 overdue	end stage renal failure, latent tuberculosis infection	Rutgers, The State University of New Jersey	Active not recruiting	No outcome recorded
Phase 4	NCT04703075	Mar 2022 → Jun 2024	tuberculosis	Johns Hopkins University	Completed	Missed primary
Phase 4	NCT04830462	Apr 2021 → May 2023	latent tuberculosis infection, type 2 diabetes mellitus	Herlev and Gentofte Hospital	Completed	No outcome recorded
Phase 4	NCT03266991	Oct 2017 → Feb 2023	—	Aarhus University Hospital	Terminated	No outcome recorded Stop: Enrollment
Phase 4	NCT03028129	Sep 2017 → Aug 2019	pulmonary tuberculosis	Federal University of Mato Grosso	Terminated	No outcome recorded
Phase 4	NCT03237182	Jun 2017 → Dec 2022	multidrug-resistant tuberculosis	Centre for the AIDS Programme of Research in South Africa	Terminated	No outcome recorded
Phase 4	NCT03302299	Apr 2017 → Apr 2021	HIV infectious disease, alcohol abuse, tuberculosis	University of California, San Francisco	Completed	No outcome recorded
Phase 4	NCT02901288	Aug 2016 → Dec 2018	pulmonary tuberculosis	Beijing Chest Hospital	Unknown	No outcome recorded
Phase 4	NCT02477852	Apr 2015 → Dec 2017	tuberculosis, spinal	Beijing Chest Hospital	Unknown	No outcome recorded
Phase 4	NCT02057796	Sep 2014 → Apr 2018	HIV infectious disease	ANRS, Emerging Infectious Diseases	Completed	Missed primary
Phase 4	NCT01494038	Aug 2014 → Sep 2017	HIV infectious disease, tuberculosis	National Institute of Allergy and Infectious Diseases (NIAID)	Completed	No outcome recorded
Phase 4	NCT01782950	Feb 2013 → Mar 2016	tuberculosis	Makerere University	Unknown	No outcome recorded
Phase 4	NCT01380080	Oct 2011 → Jan 2015	HIV infectious disease	Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections	Completed	Missed primary
Phase 4	NCT01395654	Jul 2011 → Dec 2013	hepatitis, pulmonary tuberculosis	National Taiwan University Hospital	Unknown	No outcome recorded
Phase 4	NCT01875952	May 2010 → Jun 2012	HIV infectious disease, latent tuberculosis infection	National Institute of Public Health, Mexico	Unknown	No outcome recorded
Phase 4	NCT00728546	Jun 2008 → Nov 2015	isoniazid toxicity, tuberculosis	National Taiwan University Hospital	Unknown	No outcome recorded
Phase 4	NCT00293228	Feb 2007 → Mar 2008	tuberculosis	National Institute of Public Health, Mexico	Completed	No outcome recorded
Phase 4	NCT00405301	Dec 2006 → Jun 2008	drug-induced liver injury, tuberculosis	All India Institute of Medical Sciences	Completed	No outcome recorded
Phase 4	NCT00107887	Jun 2005 → Dec 2010	HIV infectious disease, tuberculosis	Johns Hopkins University	Completed	No outcome recorded
Phase 4	NCT00298870	Jun 2005 → ?	pulmonary tuberculosis	Osaka University	Completed	Met primary
Phase 4	NCT00164281	Nov 2004 → Jul 2009	HIV infectious disease, tuberculosis	Centers for Disease Control and Prevention	Completed	Met primary
Phase 4	NCT00216333	Dec 2003 → Jun 2007	tuberculosis	International Union Against Tuberculosis and Lung Diseases	Unknown	Missed primary
Phase 4	NCT00397709	Mar 1996 → Feb 2006	tuberculosis	Hospital Virgen de la Luz	Terminated	No outcome recorded
Phase 4	NCT00402454	Jan 1994 → Dec 1998	HIV infectious disease	Sociedad Andaluza de Enfermedades Infecciosas	Completed	No outcome recorded
Phase 4	NCT00402610	Jan 1994 → Dec 1998	HIV infectious disease, tuberculosis	Sociedad Andaluza de Enfermedades Infecciosas	Completed	Missed primary

Phase not applicable19 trials · 1 met primary · 1 missed
—	NCT07608172	May 2026 → Jun 2028 expected	pulmonary tuberculosis	Shanghai Public Health Clinical Center	Not yet recruiting	No outcome recorded
—	NCT07086820	Oct 2025 → May 2028 expected	latent tuberculosis infection	Pontificia Universidad Catolica de Chile	Recruiting	No outcome recorded
—	NCT06512831	Jun 2023 → Feb 2024	isoniazid toxicity, tuberculosis	West China Hospital	Completed	No outcome recorded
—	NCT05249699	Apr 2022 → Jul 2023	disease related to solid organ transplantation, isoniazid toxicity, tuberculosis	West China Hospital	Unknown	No outcome recorded
—	NCT03787940	Mar 2019 → Dec 2021	meningeal tuberculosis	Beijing Chest Hospital	Unknown	No outcome recorded
—	NCT03900858	Dec 2018 → Jan 2022	silicotuberculosis	Huashan Hospital	Unknown	No outcome recorded
—	NCT03665402	May → Dec 2018	drug-induced liver injury, tuberculosis	Seoul National University Hospital	Completed	No outcome recorded
—	NCT03089983	Aug 2017 → Apr 2024	HIV infectious disease, hepatitis, opiate dependence, tuberculosis	Yale University	Completed	Missed primary
—	NCT01926379	Jul 2013 → Feb 2016	HIV infectious disease, tuberculosis	Columbia University	Completed	No outcome recorded
—	NCT01550705	Mar 2012 → Dec 2015	X-linked erythropoietic protoporphyria	University of Utah	Terminated	No outcome recorded
—	NCT01087190	Jun 2010 → May 2013	—	Asan Medical Center	Completed	No outcome recorded
—	NCT00463086	Nov 2007 → Nov 2011	HIV infectious disease, latent tuberculosis infection	University of Cape Town	Completed	Met primary
—	NCT02076685	Nov 2007 → Nov 2015	poisoning	National Taiwan University Hospital	Unknown	No outcome recorded
—	NCT00018083	—	HIV infectious disease, tuberculosis	National Center for Research Resources (NCRR)	Unknown	No outcome recorded
—	NCT00000796	? → Oct 1998	HIV infectious disease, pulmonary tuberculosis	National Institute of Allergy and Infectious Diseases (NIAID)	Completed	No outcome recorded
—	NCT00000950	? → May 2002	HIV infectious disease, tuberculosis	National Institute of Allergy and Infectious Diseases (NIAID)	Completed	No outcome recorded
—	NCT00000636	? → Oct 1997	HIV infectious disease, tuberculosis	National Institute of Allergy and Infectious Diseases (NIAID)	Completed	No outcome recorded
—	NCT00000959	? → Jun 1996	HIV infectious disease, tuberculosis	National Institute of Allergy and Infectious Diseases (NIAID)	Completed	No outcome recorded
—	NCT00000638	? → Sep 1999	HIV infectious disease, tuberculosis	National Institute of Allergy and Infectious Diseases (NIAID)	Completed	No outcome recorded

Comparator or background therapy103 trials
Phase 0	NCT02099240 Comparator	Mar 2014 → Nov 2018	osteomyelitis	University of Louisville	Terminated	No outcome recorded Stop: Enrollment
Phase 1	NCT07058090 Comparator	Jul → Dec 2025 overdue	drug-induced liver injury, tuberculosis	Liaquat National Hospital & Medical College	Not yet recruiting	No outcome recorded
Phase 1	NCT05592223 Comparator	Dec 2022 → Aug 2023	tuberculosis	Fred Hutchinson Cancer Center	Completed	No outcome recorded
Phase 1	NCT04424264 Background	Dec 2019 → Oct 2020	HIV infectious disease, tuberculosis	Professor Francois Venter	Completed	No outcome recorded
Phase 1	NCT02832778 Background	Nov 2016 → Jan 2018	HIV infectious disease	St Stephens Aids Trust	Unknown	No outcome recorded
Phase 1	NCT01838200 Background	Mar 2014 → Aug 2015	metastatic melanoma	Ludwig Institute for Cancer Research	Terminated	No outcome recorded Stop: Enrollment
Phase 1	NCT00004736 Background	—	HIV infectious disease, tuberculosis	National Institute of Allergy and Infectious Diseases (NIAID)	Completed	No outcome recorded
Phase 1/2	NCT07124559 Background	Jul 2026 → Jan 2028 expected	tuberculosis	National Institute of Allergy and Infectious Diseases (NIAID)	Not yet recruiting	No outcome recorded
Phase 1/2	NCT03678688 Comparator	Oct 2018 → Feb 2022	pulmonary tuberculosis	Otsuka Pharmaceutical Development & Commercialization, Inc.	Completed	Missed primary
Phase 1/2	NCT02958709 Background	Feb 2017 → Nov 2020	meningeal tuberculosis	Johns Hopkins University	Completed	No outcome recorded
Phase 1/2	NCT00396084 Comparator	Feb 2004 → Nov 2007	tuberculosis	National Institute of Allergy and Infectious Diseases (NIAID)	Completed	No outcome recorded
Phase 2	NCT07656012 Background	Oct 2026 → Sep 2030 expected	tuberculosis	University of Wisconsin, Madison	Not yet recruiting	No outcome recorded
Phase 2	NCT07773610 Comparator	Sep 2026 → Dec 2027 expected	pulmonary tuberculosis	TASK Applied Science	Not yet recruiting	No outcome recorded
Phase 2	NCT07467252 Comparator	Sep 2026 → Dec 2027 expected	pulmonary tuberculosis	Ministry of Health, Saudi Arabia	Not yet recruiting	No outcome recorded
Phase 2	NCT07595042 Background	Jul 2026 → Jun 2029 expected	tuberculosis	National Institute of Allergy and Infectious Diseases (NIAID)	Not yet recruiting	No outcome recorded
Phase 2	NCT07350174 Comparator	Mar 2026 → Mar 2028 expected	meningeal tuberculosis	BioVersys AG	Not yet recruiting	No outcome recorded
Phase 2	NCT07303699 Background	Jan 2026 → Mar 2027 expected	pulmonary tuberculosis	Obafemi Awolowo University Teaching Hospital	Recruiting	No outcome recorded
Phase 2	NCT07073638 Background	Oct 2025 → Sep 2026 overdue	pulmonary tuberculosis	Thirty Respiratory Limited	Recruiting	No outcome recorded
Phase 2	NCT06446245 Background	Aug 2025 → Nov 2027 expected	meningeal tuberculosis	National University Hospital, Singapore	Recruiting	No outcome recorded
Phase 2	NCT06917495 Background	Apr 2025 → Dec 2027 expected	tuberculosis, spinal	Shandong University	Not yet recruiting	No outcome recorded
Phase 2	NCT06192160 Background	Mar 2025 → Nov 2026 expected	pulmonary tuberculosis	National Institute of Allergy and Infectious Diseases (NIAID)	Recruiting	No outcome recorded
Phase 2	NCT06748937 Comparator	Mar 2025 → Mar 2026 overdue	pulmonary tuberculosis	TASK Applied Science	Recruiting	No outcome recorded
Phase 2	NCT05630872 Background	Feb 2024 → May 2025	tuberculosis	National Institute of Allergy and Infectious Diseases (NIAID)	Completed	No outcome recorded
Phase 2	NCT06114628 Comparator	Jan 2024 → Feb 2027 expected	pulmonary tuberculosis	University College, London	Recruiting	No outcome recorded
Phase 2	NCT06199921 Comparator	Jan 2024 → Mar 2026 overdue	pulmonary tuberculosis	Obafemi Awolowo University Teaching Hospital	Recruiting	No outcome recorded
Phase 2	NCT05556746 Comparator	Nov 2023 → Jun 2025 overdue	HIV infectious disease, pulmonary tuberculosis	Brigham and Women's Hospital	Active not recruiting	No outcome recorded
Phase 2	NCT06058299 Comparator	Oct 2023 → Dec 2024 overdue	pulmonary tuberculosis	Global Alliance for TB Drug Development	Active not recruiting	No outcome recorded
Phase 2	NCT06224036 Comparator	Oct 2023 → Mar 2024	drug-resistant tuberculosis	Beijing Chest Hospital	Unknown	Met primary
Phase 2	NCT05534750 Comparator	Apr 2023 → Apr 2026 overdue	multidrug-resistant tuberculosis	Assistance Publique - Hôpitaux de Paris	Recruiting	No outcome recorded
Phase 2	NCT05473195 Comparator	Dec 2022 → Apr 2024	primary pulmonary tuberculosis	TASK Applied Science	Completed	No outcome recorded
Phase 2	NCT04694586 Background	Nov 2022 → May 2024	pulmonary tuberculosis	University Hospital, Linkoeping	Suspended	No outcome recorded Stop: Enrollment
Phase 2	NCT05221502 Comparator	Apr 2022 → Apr 2024	pulmonary tuberculosis	Otsuka Pharmaceutical Development & Commercialization, Inc.	Completed	Met primary
Phase 2	NCT04930744 Background	Aug 2021 → Apr 2025	coinfection, pulmonary tuberculosis	University of Massachusetts, Worcester	Completed	No outcome recorded
Phase 2	NCT03891901 Background	Oct 2020 → Aug 2022	tuberculosis	National Institute of Allergy and Infectious Diseases (NIAID)	Completed	No outcome recorded
Phase 2	NCT04504851 Background	Aug 2020 → Mar 2021	pulmonary tuberculosis	National University Hospital, Singapore	Unknown	Missed primary
Phase 2	NCT04176250 Comparator	Jan 2020 → Oct 2022	pulmonary tuberculosis	Gates Medical Research Institute	Completed	No outcome recorded
Phase 2	NCT03927313 Background	Jun 2019 → Mar 2021	HIV infectious disease, meningeal tuberculosis	University of Cape Town	Completed	No outcome recorded
Phase 2	NCT03563599 Comparator	Jul 2018 → Sep 2019	tuberculosis	Qurient Co., Ltd.	Completed	No outcome recorded
Phase 2	NCT03334734 Comparator	Dec 2016 → Sep 2017	tuberculosis	Nearmedic Plus LLC	Terminated	No outcome recorded Stop: Enrollment
Phase 2	NCT02836483 Comparator	Dec 2016 → Jul 2019	pulmonary tuberculosis	LigaChem Biosciences, Inc.	Completed	No outcome recorded
Phase 2	NCT03281226 Comparator	Dec 2016 → Jun 2019	AIDS, pulmonary tuberculosis	Fundação de Medicina Tropical Dr. Heitor Vieira Dourado	Unknown	No outcome recorded
Phase 2	NCT01589497 Comparator	Jun 2015 → Jan 2016	tuberculosis	Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections	Completed	No outcome recorded
Phase 2	NCT02256696 Background	Apr 2015 → May 2022	pulmonary tuberculosis	Johns Hopkins University	Completed	Mixed
Phase 2	NCT02279875 Comparator	Nov 2014 → Nov 2016	pulmonary tuberculosis	Global Alliance for TB Drug Development	Completed	No outcome recorded
Phase 2	NCT02193776 Comparator	Oct 2014 → Feb 2016	tuberculosis	Global Alliance for TB Drug Development	Completed	Met primary
Phase 2	NCT01601626 Background	Jul 2013 → Jan 2017	HIV infectious disease, tuberculosis	Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections	Terminated	No outcome recorded
Phase 2	NCT02121314 Comparator	Jul 2013 → Apr 2014	tuberculosis	University Medical Center Groningen	Completed	No outcome recorded
Phase 2	NCT01785186 Background	Apr 2013 → Sep 2014	pulmonary tuberculosis	Michael Hoelscher	Completed	Met primary
Phase 2	NCT01516203 Comparator	Dec 2012 → Dec 2013	tuberculosis	National Institute of Allergy and Infectious Diseases (NIAID)	Completed	Met primary
Phase 2	NCT01225640 Comparator	Aug → Dec 2011	tuberculosis	Sequella, Inc.	Completed	No outcome recorded
Phase 2	NCT01215851 Comparator	Oct 2010 → May 2011	pulmonary tuberculosis	Global Alliance for TB Drug Development	Completed	Met primary
Phase 2	NCT00728507 Background	Nov 2009 → Apr 2013	tuberculosis	Johns Hopkins University	Terminated	Missed primary Stop: Business
Phase 2	NCT00144417 Comparator	Feb 2006 → Jun 2007	tuberculosis	Centers for Disease Control and Prevention	Completed	Missed primary
Phase 2	NCT00164463 Comparator	Jul 2004 → Aug 2007	tuberculosis	Centers for Disease Control and Prevention	Completed	No outcome recorded
Phase 2	NCT00140309 Background	Jul 2003 → Dec 2005	pulmonary tuberculosis	Centers for Disease Control and Prevention	Completed	Missed primary
Phase 2/3	NCT05766267 Comparator	Nov 2023 → Dec 2026 expected	pulmonary tuberculosis	Centers for Disease Control and Prevention	Active not recruiting	No outcome recorded
Phase 2/3	NCT06618573 Comparator	Aug 2022 → Dec 2025 overdue	systemic lupus erythematosus, tuberculosis	Padjadjaran University	Recruiting	No outcome recorded
Phase 2/3	NCT03474029 Comparator	Aug 2019 → Dec 2029 expected	latent tuberculosis infection	Centers for Disease Control and Prevention	Recruiting	No outcome recorded
Phase 2/3	NCT03338621 Comparator	Jul 2018 → Jul 2021	multidrug-resistant tuberculosis, pulmonary tuberculosis	Global Alliance for TB Drug Development	Completed	Met primary
Phase 2/3	NCT03474198 Background	Mar 2018 → Jan 2022	pulmonary tuberculosis	University College, London	Completed	Mixed
Phase 2/3	NCT02467608 Background	Dec 2012 → Jan 2019	pulmonary tuberculosis	Orient Pharma Co., Ltd.	Completed	No outcome recorded
Phase 2/3	NCT00495326 Background	Dec 2007 → Apr 2011	AIDS, tuberculosis	French National Agency for Research on AIDS and Viral Hepatitis	Completed	Missed primary
Phase 3	NCT07076225 Comparator	Jul 2025 → Jan 2030 expected	pulmonary tuberculosis	Shenzhen Third People's Hospital	Not yet recruiting	No outcome recorded
Phase 3	NCT06905522 Comparator	Jun 2025 → Jan 2029 expected	pulmonary tuberculosis	Shenzhen Third People's Hospital	Recruiting	No outcome recorded
Phase 3	NCT06022146 Comparator	Sep 2023 → Sep 2026 overdue	latent tuberculosis infection	Huashan Hospital	Recruiting	No outcome recorded
Phase 3	NCT04951986 Background	Aug 2021 → Dec 2025 overdue	HIV infectious disease, tuberculosis	University of Cape Town	Active not recruiting	No outcome recorded
Phase 3	NCT04260477 Comparator	Mar 2021 → Jun 2025 overdue	multidrug-resistant tuberculosis, pulmonary tuberculosis	Institute of Tropical Medicine, Belgium	Recruiting	No outcome recorded
Phase 3	NCT04145258 Background	Feb 2021 → Sep 2026 overdue	meningeal tuberculosis	ANRS, Emerging Infectious Diseases	Recruiting	No outcome recorded
Phase 3	NCT04485156 Background	Sep 2020 → Aug 2025 overdue	pulmonary tuberculosis	Seoul National University Hospital	Not yet recruiting	Missed primary
Phase 3	NCT04062201 Comparator	Aug 2019 → Apr 2024	extensively drug-resistant tuberculosis, multidrug-resistant tuberculosis, rifampicin-resistant tuberculosis	Wits Health Consortium (Pty) Ltd	Completed	No outcome recorded
Phase 3	NCT02581527 Background	Feb 2017 → Jan 2022	pulmonary tuberculosis	St George's, University of London	Completed	Missed primary
Phase 3	NCT02980016 Comparator	Nov 2016 → Oct 2019	HIV infectious disease, tuberculosis	The Aurum Institute NPC	Completed	No outcome recorded
Phase 3	NCT02563327 Background	May 2016 → Aug 2021	tuberculosis	Centers for Disease Control and Prevention	Completed	No outcome recorded
Phase 3	NCT02342886 Comparator	Feb 2015 → Jan 2018	multidrug-resistant tuberculosis, pulmonary tuberculosis	Global Alliance for TB Drug Development	Completed	No outcome recorded
Phase 3	NCT02153528 Background	Nov 2014 → Aug 2017	pulmonary tuberculosis	Damien Foundation	Completed	No outcome recorded
Phase 3	NCT02208427 Comparator	Aug 2014 → Dec 2016	latent tuberculosis infection	National Taiwan University Hospital	Unknown	Met primary
Phase 3	NCT01761201 Comparator	Jan 2012 → Feb 2014	disease related to solid organ transplantation, latent tuberculosis infection	Andalusian Public Foundation for Health Research in Seville	Terminated	No outcome recorded Stop: Enrollment
Phase 3	NCT00170209 Comparator	Aug 2011 → Nov 2014	latent tuberculosis infection	McGill University	Completed	No outcome recorded
Phase 3	NCT00931736 Comparator	Aug 2009 → Apr 2017	latent tuberculosis infection	McGill University	Completed	No outcome recorded
Phase 3	NCT00571753 Comparator	Jun 2008 → Dec 2011	pulmonary tuberculosis	University of Cologne	Terminated	No outcome recorded Stop: Enrollment
Phase 3	NCT00128206 Comparator	Nov 2004 → Oct 2008	tuberculosis	University of California, San Francisco	Completed	No outcome recorded
Phase 3	NCT00057122 Comparator	Sep 2002 → Nov 2008	HIV infectious disease, tuberculosis	National Institute of Allergy and Infectious Diseases (NIAID)	Completed	No outcome recorded
Phase 3	NCT00023452 Comparator	Jun 2001 → Oct 2010	tuberculosis	Centers for Disease Control and Prevention	Completed	Met primary
Phase 4	NCT05021731 Comparator	Apr 2024 → Apr 2025	kidney failure, latent tuberculosis infection	Miguel Santin	Unknown	No outcome recorded
Phase 4	NCT06403943 Background	May 2023 → Oct 2026 expected	pulmonary tuberculosis	Beijing Chest Hospital	Recruiting	No outcome recorded
Phase 4	NCT07811518 Comparator	Aug 2022 → Aug 2026 overdue	latent tuberculosis infection	Affiliated Hospital of Nantong University	Recruiting	No outcome recorded
Phase 4	NCT03867136 Comparator	Jun 2020 → Aug 2024	multidrug-resistant tuberculosis	Huashan Hospital	Completed	No outcome recorded
Phase 4	NCT03278483 Comparator	Feb 2019	tuberculosis, type 2 diabetes mellitus	National Institute of Public Health, Mexico	Completed	No outcome recorded
Phase 4	NCT06874725 Comparator	Apr 2018 → Apr 2024 overdue	latent tuberculosis infection	Taichung Veterans General Hospital	Active not recruiting	No outcome recorded
Phase 4	NCT03561753 Comparator	Dec 2017 → Dec 2019	pulmonary tuberculosis	Shanghai Pulmonary Hospital, Shanghai, China	Completed	No outcome recorded
Phase 4	NCT02231229 Comparator	Jul 2014 → Jul 2018	tuberculosis	Assistance Publique - Hôpitaux de Paris	Completed	No outcome recorded
Phase 4	NCT02331823 Comparator	Jun 2013 → Dec 2015	pulmonary tuberculosis	Shanghai Pulmonary Hospital, Shanghai, China	Unknown	No outcome recorded
Phase 4	NCT03498534 Comparator	Sep → Dec 2012	diabetes mellitus, latent tuberculosis infection	National Institute of Public Health, Mexico	Withdrawn	No outcome recorded
Phase 4	NCT01223534 Comparator	Jul 2010 → Feb 2016	latent tuberculosis infection	Hospital Universitari de Bellvitge	Completed	No outcome recorded
—	NCT04187469 Background	Mar 2020 → Feb 2023	pulmonary tuberculosis	Fifth Affiliated Hospital, Sun Yat-Sen University	Unknown	No outcome recorded
—	NCT02554318 Background	Nov 2013 → Feb 2015	pulmonary tuberculosis	University of Giessen	Completed	No outcome recorded
—	NCT01677871 Comparator	Sep 2012 → Sep 2014	tuberculosis	Institute of Liver and Biliary Sciences, India	Unknown	No outcome recorded
—	NCT01344148 Background	Feb 2009 → Jun 2011	AIDS	Shanghai Public Health Clinical Center	Unknown	No outcome recorded
—	NCT00737724 Background	Mar 2008 → Feb 2011	AIDS, tuberculosis	National Institute of Respiratory Diseases	Terminated	No outcome recorded
—	NCT00164450 Comparator	Sep 2005 → Aug 2008	tuberculosis	Centers for Disease Control and Prevention	Completed	No outcome recorded
—	NCT00130325 Comparator	Oct 2004 → Oct 2008	tuberculosis	Medical Research Council Unit, The Gambia	Completed	No outcome recorded
—	NCT00023387 Background	Mar 2000 → May 2001	tuberculosis	Centers for Disease Control and Prevention	Completed	No outcome recorded
—	NCT00004740 Background	Feb 1995 → ?	tuberculosis	National Institute on Drug Abuse (NIDA)	Unknown	No outcome recorded

News releases announcing trial results or a regulatory action · 2

Date	Issuer	Release
2025-11-19	Global Alliance for TB Drug Development	Results Phase 2 Clinical Trial Results Show Potential to Shorten TB Treatment Time tballiance.org ↗ The 100 mg SPaL regimen had greater activity against TB than the standard of care HRZE (isoniazid, rifampin, pyrazinamide, and ethambutol), indicating the potential to shorten treatment time for active TB.
2014-09-07	Global Alliance for TB Drug Development	Results Results of Phase 3 Clinical Trial of New Tuberculosis Drug Regimen Published in New England Journal of Medicine tballiance.org ↗ The study found that, while the experimental regimens initially killed more TB bacteria than the standard regimen, patients receiving those shortened regimens were more likely to relapse than those taking the standard treatment.

All press releases naming this drug 2 releases

Date	Issuer	Release
2025-11-19	Global Alliance for TB Drug Development	Phase 2 Clinical Trial Results Show Potential to Shorten TB Treatment Time tballiance.org ↗
2014-09-07	Global Alliance for TB Drug Development	Results of Phase 3 Clinical Trial of New Tuberculosis Drug Regimen Published in New England Journal of Medicine tballiance.org ↗

Evidence & citations 12 cited values

Every value below carries the sentence it was read from. 227 sources stand behind the page.

Field	Value	Cited text
Known as	Isoniazid	“empiric initiation of the enhanced spectrum antimicrobial therapy regimen (rifampin, isoniazid, linezolid, and levofloxacin) for 14 days plus standard care which includes...” NCT07332325 ↗ 223 “INTERVENTIONS: Patients were randomized to receive daily treatment with 4 drugs (rifampicin, isoniazid, pyrazinamide, ethambutol) given as an FDC (n = 798 patients) or...” PMID 21486974 ↗ Apr 2011 “This product is a compound preparation, consisting of 0.15g of rifampicin (C43H58N4O12), 0.075g of isoniazid (C6H7N3O), 0.4g of pyrazinamide (C5H5N3O), and 0.275g of ethambutol...” NCT06224036 ↗ “Increased doses of rifampicin (R) to 35±5 mg/kg daily and isoniazid (H) 10±2 mg/kg daily together with standard-dose of pyrazinamide (Z) 20-30 mg/kg daily + ethambutol (E)...” NCT04738812 ↗ “FDC intensive phase containing 150 mg of rifampicin, 75 mg of isoniazid not 300mg, 400 mg of pyrazinamide, and 275 mg of ethambutol, while FDC continuation phase containing...” NCT05005637 ↗ “The standard six-month regimen is eight weeks of daily treatment with isoniazid, rifampin, ethambutol, and pyrazinamide followed by sixteen weeks of isoniazid and rifampin.” NCT03561753 ↗ “This study aimed to quantify the influence of food on the pharmacokinetics of isoniazid, rifampicin, ethambutol and pyrazinamide in TB patients starting anti-TB treatment.” PMID 26661397 ↗ Dec 2015 “SOC plus 6 months of tuberculosis treatment (isoniazid, rifampicin, pyrazinamide, and ethambutol for 2 months, plus isoniazid and rifampicin for 4 subsequent months)” PMID 42468541 ↗ Jul 2026 “provision of tuberculin skin tests, and use of isoniazid preventive therapy in Brazilian HIV clinics significantly reduced incident tuberculosis and death” PMID 23954450 ↗ Aug 2013 “RIFATER © (Isoniazid + Rifampicin + Pyrazinamide) + Ethambutol (13.5-20 mg / kg / day) for 2 months then RIFINAH © (Isoniazid + Rifampicin) for 4 months” NCT04117698 ↗ “using regimens containing isoniazid (INH \[H\]), rifampin (RIF \[R\]), pyrazinamide (PZA \[Z\]), moxifloxacin (MXF \[M\]), and ethambutol (EMB \[E\]).” NCT02371681 ↗ Show 213 more sources
Known as	Generic name: Isoniazid.	“Generic name: Isoniazid.” NCT01761201 ↗
Known as	INH	“This study is a phase I, single-center, open label, randomized controlled clinical trial assessing the effect of pre-clearance of latent Mycobacterium tuberculosis (MTB) by...” NCT01119521 ↗ 38 “To evaluate and compare the safety and effectiveness of a one-year course of isoniazid (INH) versus a two-month course of rifampin plus pyrazinamide for the prevention of...” NCT00000638 ↗ “Standard of care involves Isoniazid Prevention Therapy (IPT) - the administration of Isoniazid (INH) to individuals with latent infection with M. tuberculosis in order to...” NCT01926379 ↗ “Patients will be screened to confirm TBM diagnosis, will receive 8 weeks of study treatment, and then will receive isoniazid (INH)/rifampicin for an additional 40 weeks, to...” NCT02958709 ↗ “Many people living with human immunodeficiency virus (PLWH) require TB treatment with isoniazid (INH) and rifampicin (RIF), which affect cytochrome P450 and antiretroviral exposure.” PMID 30084943 ↗ Jan 2019 “Isoniazid (INH) is a first-line antituberculous medication discovered in 1952 and used in the prevention (alone) and treatment (in combination) of tuberculosis.” NCT00816426 ↗ “Randomized controlled trial (RCT) of isoniazid (INH) vs. no INH to prevent Mycobacterium tuberculosis infection in HIV-exposed uninfected (HEU) infants.” NCT02613169 ↗ “compared with an isoniazid (INH) control arm in patients with newly-diagnosed sputum smear-positive pulmonary tuberculosis (TB).” NCT00396084 ↗ “To evaluate the safety and effectiveness of a 6-month course of isoniazid ( INH ) in the prevention of clinical tuberculosis.” NCT00000959 ↗ “Isoniazid prophylaxis:300 mg of INH once a day before breakfast for six months, starting one month after study inclusion” NCT00495651 ↗ “The Arkansas colorimetric method monitors adherence to isoniazid (INH) by the detection of INH metabolites in urine.” PMID 24903787 ↗ May 2014 Show 28 more sources
Known as	Isoniazid (H)	“Isoniazid (H)” NCT07656012 ↗
Known as	Isoniazid I INH	“Isoniazid I INH” NCT03900858 ↗
Known as	isoniazid tablets	“isoniazid tablets” NCT02331823 ↗
Known as	isonicotinic acid hydrazine	“This study is a phase I, single-center, open label, randomized controlled clinical trial assessing the effect of pre-clearance of latent Mycobacterium tuberculosis (MTB) by...” NCT01119521 ↗
Known as	Rifinah	“Isoniazid (Rifinah)” NCT00728546 ↗
Known as	RIMIFON	“of Isoniazid (RIMIFON®)” NCT05534750 ↗
Action	Inhibit	“Its primary action is to inhibit the synthesis of long-chain mycolic acids” NCT02409290 ↗
Modality	Small molecule	“This product is a compound preparation, consisting of 0.15g of rifampicin (C43H58N4O12), 0.075g of isoniazid (C6H7N3O)” NCT06224036 ↗
Route	Oral	“self-administer oral isoniazid” NCT00004740 ↗