drugset / Trial / NCT01398618

Comparing Two Preventive Regimens for Latent Tuberculosis Infection (LTBI)

NCT01398618

Phase 3 Unknown 300 enrolled National Taiwan University Hospital
RandomizedParallel-groupOpen-labelPrevention

Summary

Though still an endemic area, the incidence of tuberculosis (TB) in Taiwan is decreasing in recent years. Further reduction in TB incidence, or even elimination should rely on treatment for LTBI. However, which is the cost-effective screening method or what is the cost-effective regimen in Taiwan is still unclear. Therefore, the investigators designed this prospective study to follow up adult household contacts with LTBI for 2 years and compare the efficacy of 9-month isoniazid and 4-month rifampicin).

Timeline

Start
2011-05
Primary completion
2013-12
Completion
2013-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Isoniazid Small molecule 300 mg
Subject Rifampin Small molecule 600 mg