PK Study of Anti-TB Drugs

Summary

This is a prospective descriptive and pharmacokinetic study will be conducted among newly diagnosed patients registered in the two SMRU TB clinics located on the Thai-Myanmar border. This study aims to recruit (1) 30 adults with HIV co-infection and (2) 30 adults without HIV co-infection in one year. Patients will be given the standard 6 month anti-TB drugs as per WHO guidelines.

Timeline

Start

2015-07-07

Primary completion

2018-01-14

Completion

2018-01-14

Publications

• Phyo AP, Hoglund RM, Saito M, Thi SS, Swe LL, Chotsiri P, Aung HKK, Tun WPP, Maung BM, Pateekham C, Watthanaworawit W, Gornsawun G, White NJ, Nosten F, Tarning J. Altered Pharmacokinetics and Delayed Sputum Conversion in Tuberculosis Patients Co-Infected With HIV. Trop Med Int Health. 2026 May 19. doi: 10.1111/tmi.70165. Online ahead of print.

Drugs

Indications