drugset / Trial / NCT00002035

Double-Blind Comparison of the Efficacy of Continued Zidovudine Versus 2',3'-Dideoxyinosine (ddI) (BMY-40900) for the Treatment of Patients With AIDS or AIDS-Related Complex and Increasing Symptomatology Despite Treatment With Zidovudine

NCT00002035

Completed 300 enrolled Bristol-Myers Squibb
Double-blindTreatment

Summary

To compare the efficacy and safety of orally administered didanosine (ddI) with orally administered zidovudine (AZT) in the treatment of patients who exhibit increasing clinical deterioration despite treatment with AZT.

Timeline

Start
Primary completion
Completion
1992-04

Publications

  • Background Ruedy N, et al. Results of long term follow-up of a double blind study of ddI vs continued AZT among individuals with CD4s 200-500/mm3. Int Conf AIDS. 1994 Aug 7-12;10(2):16 (abstract no 358B)

Drugs

EvaluationDrugModalityDoseRoute
Subject Didanosine Small molecule Oral
Subject Zidovudine Small molecule Oral