drugset / Trial / NCT00002317
A Study of Trimetrexate Plus Leucovorin in Children With Pneumocystis Carinii Pneumonia
Completed
U.S. Bioscience
Open-labelTreatment
Summary
To evaluate the safety and efficacy of trimetrexate glucuronate with leucovorin protection in pediatric patients with Pneumocystis carinii pneumonia (PCP) who are refractory to or have demonstrated severe or life-threatening toxicities to standard therapies (e.g., TMP/SMX or parenteral pentamidine).
Timeline
- Start
- —
- Primary completion
- —
- Completion
- —
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Trimetrexate glucuronate | Unknown | — | Intravenous |
| Background | Leucovorin | Small molecule | — | Intravenous |