Drugs / Trimetrexate glucuronate
last change Jun 2006 re-read 2 minutes ago

Trimetrexate glucuronate

also known as Neutrexin · TMTX
Developed for
pneumocystosis · colorectal cancer · leukemia · lymphoma · sarcoma
Investigated by
U.S. Bioscience · Grupo Oncologico Cooperativo del Sur · Memorial Sloan Kettering Cancer Center · National Cancer Institute (NCI)

Regulatory milestones approvals, filings & regulatory actions · 1 recorded

MilestoneJurisdictionBrandIndicationDateSentence it was read from
Approved US (FDA) NEUTREXIN 1993-12-17 fda.gov

Trials 4 · a red edge is where a trial was stopped

19931994199519961997199819992000200120022003200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 22 trials
Phase 2 NCT00003446 Dec 1997 → Aug 2005 colorectal cancer Grupo Oncologico Cooperativo del Sur Completed No outcome recorded
Phase 2 NCT00002738 Jan 1996 → Jun 2006 leukemia, lymphoma, sarcoma Memorial Sloan Kettering Cancer Center Completed No outcome recorded
Phase not applicable2 trials
NCT00002103 HIV infectious disease, pneumocystosis U.S. Bioscience Completed No outcome recorded
NCT00002317 HIV infectious disease, pneumocystosis U.S. Bioscience Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as Trimetrexate glucuronate ClinicalTrials.gov intervention name — accepted as the source's own label NCT00002317
3

NCT00002738

NCT00003446

NCT00002103

Known as Neutrexin “A Compassionate Treatment Protocol for the Use of Trimetrexate Glucuronate (Neutrexin) With Leucovorin Protection for European Adult Patients (>= 13 Years Old) With...” NCT00002103
Known as TMTX “Patients receive trimetrexate glucuronate (TMTX) IV over 1 hour on day 1.” NCT00003446
Route Intravenous “Patients receive intravenous infusions of trimetrexate glucuronate and leucovorin for 21 days.” NCT00002103