drugset / Trial / NCT00003446

Chemotherapy in Treating Patients With Recurrent or Metastatic Colorectal Cancer

NCT00003446

Treatment

Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of trimetrexate glucuronate, fluorouracil, and leucovorin in treating patients with recurrent or metastatic colorectal cancer.

Timeline

Start
1997-12
Primary completion
Completion
2005-08

Drugs

EvaluationDrugModalityDoseRoute
Subject Leucovorin Small molecule Intravenous
Subject Trimetrexate glucuronate Unknown Intravenous
Subject fluorouracil Small molecule Intravenous

Indications