drugset / Trial / NCT00002465
High-Dose Megestrol in Treating Patients With Metastatic Breast Cancer, Endometrial Cancer, or Mesothelioma
Treatment
Summary
RATIONALE: Some hormones can stimulate the growth of some types of cancer cells. Hormone therapy using megestrol may fight cancer by reducing the production of these hormones. PURPOSE: Phase I/II trial to study the effectiveness of high-dose megestrol in treating patients with metastatic breast cancer, endometrial cancer, or mesothelioma which cannot be treated with surgery or radiation therapy.
Timeline
- Start
- 1987-12
- Primary completion
- —
- Completion
- —
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Megestrol Acetate | Other / unclassified | 480 mg | Oral |
| Subject | Megestrol Acetate | Other / unclassified | 800 mg | Oral |
| Subject | Megestrol Acetate | Other / unclassified | 1280 mg | Oral |
| Subject | Megestrol Acetate | Other / unclassified | 1600 mg | Oral |