drugset / Trial / NCT00002560

Monoclonal Antibody Therapy Plus Sargramostin in Treating Patients With Advanced Neuroblastoma

NCT00002560

Phase 2 Completed 40 enrolled Memorial Sloan Kettering Cancer Center
Treatment

Summary

RATIONALE: Monoclonal antibodies can locate tumor cells and either kill them or deliver tumor-killing substances to them without harming normal cells. Combining colony-stimulating factors, such as sargramostim, with monoclonal antibodies may be an effective treatment for advanced neuroblastoma. PURPOSE: Phase II trial to study the effectiveness of monoclonal antibody 3F8 plus sargramostim in treating patients who have advanced neuroblastoma.

Timeline

Start
1994-02
Primary completion
2005-04
Completion
2005-04

Drugs

EvaluationDrugModalityDoseRoute
Subject 3F8 Monoclonal antibody Intravenous
Subject sargramostim Protein / enzyme biologic Intravenous

Indications