Drugs / sargramostim
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sargramostim

Protein / enzyme biologic

Developed for
cutaneous melanoma · neuroblastoma · leukemia · HIV infectious disease · lymphoma · prostate cancer · breast cancer · metastatic malignant neoplasm
+139 more · colorectal cancer · Crohn disease · metastatic melanoma · chronic hepatitis B virus infection · kidney cancer · melanoma · myelodysplastic syndrome · non-small cell lung carcinoma · plasma cell myeloma · acute myeloid leukemia · autoimmune pulmonary alveolar proteinosis · cancer of unknown primary site · lung cancer · prostate neoplasm · COVID-19 · diffuse large B-cell lymphoma · glioblastoma · head and neck cancer · Alzheimer disease · fallopian tube cancer · male breast carcinoma · malignant pancreatic neoplasm · osteosarcoma · pancreatic adenocarcinoma · Parkinson disease · peripheral arterial disease · sarcoma · acute respiratory distress syndrome · B-cell chronic lymphocytic leukemia · cancer · chronic myeloid leukemia · colorectal carcinoma · cytomegalovirus retinitis · esophageal cancer · female breast carcinoma · follicular lymphoma · gastric cancer · gliosarcoma · infectious disease with sepsis · infertility disorder · inflammatory breast carcinoma · iris melanoma · Kaposi's sarcoma · medium/large size posterior uveal melanoma · mouth disorder · myelodysplastic/myeloproliferative disease · ocular melanoma · ocular melanoma with extraocular extension · ovarian cancer · ovarian endometrioid adenocarcinoma · peritoneum cancer · prostate carcinoma · radiation-induced disorder · refractory malignant neoplasm · renal cell carcinoma · urinary bladder cancer · uveal melanoma · acute erythroid leukemia · acute megakaryoblastic leukemia in adult · acute myeloblastic leukemia with maturation · acute myeloblastic leukemia without maturation · acute myeloid leukemia with 11q23 abnormalities · acute myeloid leukemia with abnormal bone marrow eosinophils inv(16)(p13q22) or t(16;16)(p13;q22) · acute myeloid leukemia with minimal differentiation · acute myeloid leukemia with t(8;21)(q22;q22) translocation · acute myelomonocytic leukemia M4 · adult acute lymphoblastic leukemia · adult acute monocytic leukemia · adult acute respiratory distress syndrome · anaplastic astrocytoma · anaplastic oligoastrocytoma · anaplastic oligodendroglioma · appendicitis · biliary tract cancer · brain injury · brain stem glioma · breast carcinoma · Brenner tumor · Burkitt lymphoma · carcinoma · central nervous system neoplasm · cervical cancer · childhood ependymoma · chronic myelomonocytic leukemia · colon carcinoma · conjunctival cancer · cutaneous leishmaniasis · dendritic cell deficiency · Down syndrome · endometrial cancer · fungal infectious disease · generalized myasthenia gravis · giant cell glioblastoma · grade III prostatic intraepithelial neoplasia · graft versus host disease · HER2 positive breast carcinoma · hereditary pulmonary alveolar proteinosis · hormone-resistant prostate carcinoma · infectious disease · kidney disorder · liver cancer · metastatic malignant neoplasm in the colon · metastatic neoplasm · metastatic prostate carcinoma · mucosal melanoma · multiple organ dysfunction syndrome · Mycobacterium avium complex disease · myelodysplastic syndrome with excess blasts · myelodysplastic syndrome with multilineage dysplasia · myelodysplastic syndrome with ring sideroblasts · myeloid leukemia · myeloproliferative neoplasm, unclassifiable · nodular ganglioneuroblastoma · ovarian clear cell cystadenocarcinoma · ovarian mucinous cystadenocarcinoma · ovarian serous cystadenocarcinoma · pancreatic ductal adenocarcinoma · periodontitis · pneumonia · pouchitis · pregnancy loss, recurrent, 4 · pulmonary alveolar proteinosis · rectal cancer · rectal carcinoma · skin cancer · small cell lung carcinoma · small size posterior uveal melanoma · soft tissue neoplasm · soft tissue sarcoma · testicular germ cell tumor · transitional cell carcinoma · triple-negative breast carcinoma · undifferentiated ovarian carcinoma · uterine disorder · viral respiratory tract infection · critical illness polyneuropathy · ductal breast carcinoma in situ · immunodeficiency disease · mucositis
Investigated by
National Cancer Institute (NCI) · Bayer · Memorial Sloan Kettering Cancer Center · Genzyme, a Sanofi Company · M.D. Anderson Cancer Center · National Institute of Allergy and Infectious Diseases (NIAID)
+216 more · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins · Mayo Clinic · Partner Therapeutics, Inc. · University of Colorado, Denver · Dana-Farber Cancer Institute · National Heart, Lung, and Blood Institute (NHLBI) · Sandoz · Sanofi · Second Affiliated Hospital of Soochow University · University of California, San Francisco · Y-mAbs Therapeutics · Children's Oncology Group · Emory University · The Cleveland Clinic · University of Nebraska · Xiamen Amoytop Biotech Co., Ltd. · Alliance for Clinical Trials in Oncology · Beth Israel Deaconess Medical Center · Fred Hutchinson Cancer Center · National Cancer Institute (NCI) · National Institute on Aging (NIA) · Roswell Park Cancer Institute · Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University · The Methodist Hospital Research Institute · University of California, Irvine · University of Wisconsin, Madison · Barbara Ann Karmanos Cancer Institute · Bayer Healthcare Pharmaceuticals, Inc./Bayer Schering Pharma · Beijing 302 Hospital · Beijing Tiantan Hospital · Bristol-Myers Squibb · Centre for Endocrinology and Reproductive Medicine, Italy · Children's Hospital Colorado · Children's Hospital Medical Center, Cincinnati · Craig L Slingluff, Jr · Favrille · French Innovative Leukemia Organisation · Fundació Sant Joan de Déu · GlaxoSmithKline · Hospices Civils de Lyon · Massachusetts General Hospital · Medical Research Council · Merck Sharp & Dohme LLC · Nationwide Children's Hospital · Providence Health & Services · Schering-Plough · St. Luke's Medical Center · The First Affiliated Hospital of Xiamen University · United States Department of Defense · University Hospital Tuebingen · University of Southern California · University of Virginia · University of Washington · Washington University School of Medicine · Academic and Community Cancer Research United · Acute Leukemia French Association · Agenzia Italiana del Farmaco · Ahmad Tarhini · Akeso Biopharma Co., Ltd. · Alesund Hospital · Alzheimer's Association · American Society of Clinical Oncology · Assistance Publique - Hôpitaux de Paris · Barbara Juliane Holzknecht (Investigator) · Bavarian Nordic · Blood and Marrow Transplant Clinical Trials Network · Brigham and Women's Hospital · COL George Peoples, MD, FACS · Cancer Insight, LLC · Case Comprehensive Cancer Center · Celldex Therapeutics · Charite University, Berlin, Germany · Children's Hospital Los Angeles · Chiron Corporation · all 222 on the full record

Regulatory milestones approvals, filings & regulatory actions · 6 recorded

MilestoneJurisdictionBrandIndicationDateSentence it was read from
Approved EU (EMA) Imreplys 2025-08-21 europa.eu
Label expansions (4) US (FDA) LEUKINE 1995-09-15 – 2018-03-29 fda.gov
Approved US (FDA) LEUKINE 1991-03-05 fda.gov

Trials 297 · started per year

today
US approved 1991
EU approved 2025
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PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 04 trials
Phase 0 NCT03189706 Jun 2017 → Jun 2027 expected neuroblastoma Memorial Sloan Kettering Cancer Center Active not recruiting No outcome recorded
Phase 0 NCT04408092 Jun 2013 → Sep 2021 childhood ependymoma University of Colorado, Denver Completed No outcome recorded
Phase 0 NCT01555580 Apr 2012 → Dec 2013 generalized myasthenia gravis Muscular Dystrophy Association Unknown No outcome recorded
Phase 0 NCT00640861 Aug 2008 → Apr 2015 female breast carcinoma Mayo Clinic Completed No outcome recorded
Phase 157 trials
Phase 1 NCT05717140 Oct 2025 → Jan 2026 cutaneous melanoma, metastatic malignant neoplasm, metastatic melanoma Mayo Clinic Withdrawn No outcome recorded
Phase 1 NCT04062721 Aug 2025 → Nov 2028 expected Assistance Publique - Hôpitaux de Paris Not yet recruiting No outcome recorded
Phase 1 NCT05677633 Jan 2023 → Apr 2024 Parkinson disease University of Nebraska Completed No outcome recorded
Phase 1 NCT05366283 Apr → May 2022 Partner Therapeutics, Inc. Completed No outcome recorded
Phase 1 NCT03982004 Sep 2020 → Mar 2021 breast cancer Washington University School of Medicine Terminated No outcome recorded
Phase 1 NCT02601365 Mar → May 2019 acute respiratory distress syndrome, pneumonia, viral respiratory tract infection Milton S. Hershey Medical Center Withdrawn No outcome recorded
Phase 1 NCT03790670 Jan 2019 → Oct 2024 Parkinson disease University of Nebraska Completed No outcome recorded
Phase 1 NCT03392545 Apr 2018 → Apr 2020 brain stem glioma, glioblastoma Beijing Tiantan Hospital Unknown No outcome recorded
Phase 1 NCT03426995 Mar 2018 → May 2019 rheumatoid arthritis GlaxoSmithKline Terminated No outcome recorded
Phase 1 NCT03306589 Aug 2017 → Jan 2018 rheumatoid arthritis GlaxoSmithKline Completed No outcome recorded
Phase 1/226 trials
Phase 1/2 NCT06626516 Oct 2025 → Oct 2030 expected uveal melanoma Thomas Jefferson University Recruiting No outcome recorded
Phase 1/2 NCT06345599 May 2024 → Jan 2027 expected pancreatic ductal adenocarcinoma Second Affiliated Hospital of Soochow University Not yet recruiting No outcome recorded
Phase 1/2 NCT04211675 Sep 2022 → Dec 2026 expected neuroblastoma Nationwide Children's Hospital Recruiting No outcome recorded
Phase 1/2 NCT05131711 Nov 2021 → Nov 2022 glioblastoma Beijing Tiantan Hospital Unknown No outcome recorded
Phase 1/2 NCT04979832 Sep 2021 → Dec 2023 pouchitis Zealand University Hospital Unknown No outcome recorded
Phase 1/2 NCT04238819 Nov 2020 → Mar 2024 refractory malignant neoplasm Eli Lilly and Company Completed No outcome recorded
Phase 1/2 NCT03282188 Oct 2017 → Jul 2018 melanoma, skin cancer University of Leeds Withdrawn No outcome recorded
Phase 1/2 NCT01878565 Jun 2013 → Dec 2014 chronic hepatitis B virus infection Beijing 302 Hospital Unknown No outcome recorded
Phase 1/2 NCT02009397 Feb 2012 → Nov 2016 metastatic melanoma University of Louisville Completed No outcome recorded
Phase 1/2 NCT01355393 Jul 2011 → Nov 2013 HER2 positive breast carcinoma, male breast carcinoma University of Washington Completed No outcome recorded
Phase 2165 trials
Phase 2 NCT06989333 Jul 2025 → Jun 2027 expected autoimmune pulmonary alveolar proteinosis Jiuwu Bai Not yet recruiting No outcome recorded
Phase 2 NCT06651853 Oct 2024 → Dec 2027 expected diffuse large B-cell lymphoma The First Affiliated Hospital of Xiamen University Recruiting No outcome recorded
Phase 2 NCT06528496 Jul 2024 → Jul 2029 expected neuroblastoma Memorial Sloan Kettering Cancer Center Recruiting No outcome recorded
Phase 2 NCT05284214 Jan 2024 → Sep 2025 cancer Partner Therapeutics, Inc. Withdrawn No outcome recorded
Phase 2 NCT06112041 Oct 2023 → Oct 2026 expected carcinoma Second Affiliated Hospital of Soochow University Not yet recruiting No outcome recorded
Phase 2 NCT05482334 Oct 2023 → Sep 2026 Down syndrome University of Colorado, Denver Withdrawn No outcome recorded
Phase 2 NCT06472739 Sep 2023 → Aug 2024 Sun Yat-sen University Unknown No outcome recorded
Phase 2 NCT05817214 Feb 2023 → Nov 2025 overdue cervical cancer Zhongnan Hospital Recruiting No outcome recorded
Phase 2 NCT05603013 Oct 2022 → Jan 2024 breast carcinoma, non-small cell lung carcinoma Second Affiliated Hospital of Soochow University Unknown No outcome recorded
Phase 2 NCT05760196 Oct 2022 → Dec 2024 Xiangpan Li Unknown No outcome recorded
Show all 165 trials opens the full record — a long page
Phase 2/32 trials
Phase 2/3 NCT04642950 Dec 2020 → Oct 2021 COVID-19 Nobelpharma Completed No outcome recorded
Phase 2/3 NCT02339571 Nov 2015 → Jun 2033 expected cutaneous melanoma National Cancer Institute (NCI) Active not recruiting No outcome recorded
Phase 320 trials
Phase 3 NCT05232916 Aug 2022 → Dec 2026 expected breast cancer Greenwich LifeSciences, Inc. Recruiting No outcome recorded
Phase 3 NCT01715974 Dec 2017 → Jul 2022 pregnancy loss, recurrent, 4 Centre for Endocrinology and Reproductive Medicine, Italy Unknown No outcome recorded
Phase 3 NCT03023111 Jun 2017 → Aug 2019 cutaneous leishmaniasis Hospital Universitário Professor Edgard Santos Completed No outcome recorded
Phase 3 NCT02361528 Sep 2015 → Jun 2018 infectious disease with sepsis Hospices Civils de Lyon Completed No outcome recorded
Phase 3 NCT02327416 Oct 2014 → Dec 2018 chronic hepatitis B virus infection Tongji Hospital Unknown No outcome recorded
Phase 3 NCT01322490 Nov 2011 → Sep 2017 metastatic prostate carcinoma Bavarian Nordic Completed No outcome recorded
Phase 3 NCT01826864 Aug 2011 → Aug 2017 melanoma Jonsson Comprehensive Cancer Center Withdrawn No outcome recorded
Phase 3 NCT01041638 Dec 2009 → Dec 2013 neuroblastoma National Cancer Institute (NCI) Completed No outcome recorded
Phase 3 NCT00295165 Jan → Oct 2006 Crohn disease Genzyme, a Sanofi Company Terminated No outcome recorded
Phase 3 NCT00237575 Nov 2005 → Mar 2006 urinary bladder cancer University of Kentucky Terminated No outcome recorded
Phase 49 trials
Phase 4 NCT03769844 Dec 2018 → Dec 2023 multiple organ dysfunction syndrome Nationwide Children's Hospital Completed No outcome recorded
Phase 4 NCT02933333 Sep 2016 → Aug 2020 acute lymphoblastic leukemia, acute myeloid leukemia, hepatoblastoma, neuroblastoma +1 Xinhua Hospital, Shanghai Jiao Tong University School of Medicine Unknown No outcome recorded
Phase 4 NCT03332329 Dec 2015 → Dec 2018 chronic hepatitis B virus infection Qin Ning Unknown No outcome recorded
Phase 4 NCT02451488 May 2015 → Nov 2016 cutaneous melanoma Mayo Clinic Completed No outcome recorded
Phase 4 NCT02250768 Jul 2013 → Mar 2014 infertility disorder Vietnam National University Completed No outcome recorded
Phase 4 NCT01718210 Dec 2012 → Dec 2015 infertility disorder Centre for Endocrinology and Reproductive Medicine, Italy Completed No outcome recorded
Phase 4 NCT01495637 Dec 2011 → Feb 2022 brain injury Mark Hall Completed No outcome recorded
Phase 4 NCT01232504 Sep 2009 → Mar 2013 fungal infectious disease Xiamen Amoytop Biotech Co., Ltd. Completed No outcome recorded
Phase 4 NCT00979706 Mar 2005 → Nov 2014 HIV infectious disease Juan A. Arnaiz Completed No outcome recorded
Phase not applicable13 trials
NCT04100655 Oct 2019 → Jun 2020 uterine disorder Sir Run Run Shaw Hospital Unknown No outcome recorded
NCT05451420 Dec 2017 → Jun 2020 chronic hepatitis B virus infection Henan Provincial People's Hospital Completed No outcome recorded
NCT03164889 Jan 2017 → Jan 2018 chronic hepatitis B virus infection Beijing 302 Hospital Terminated No outcome recorded
NCT02100930 Mar 2014 → Mar 2019 neuroblastoma Memorial Sloan Kettering Cancer Center Completed No outcome recorded
NCT01408901 Sep 2011 → Aug 2017 peripheral arterial disease Northwestern University Completed No outcome recorded
NCT00673179 May 2008 → Nov 2010 osteosarcoma M.D. Anderson Cancer Center Terminated No outcome recorded
NCT00053157 Jun 2002 → Aug 2004 graft versus host disease, leukemia, lymphoma, myelodysplastic syndrome +1 Roswell Park Cancer Institute Completed No outcome recorded
NCT00006243 Oct 2000 → May 2006 melanoma National Cancer Institute (NCI) Completed No outcome recorded
NCT00899821 Jun 2000 → Dec 2004 head and neck cancer NYU Langone Health Completed No outcome recorded
NCT00002007 HIV infectious disease Sandoz Completed No outcome recorded
Phase not stated1 trial
NCT04501757 neuroblastoma Memorial Sloan Kettering Cancer Center No longer available No outcome recorded
Also used as a comparator or background therapy in 289 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 02 trials
Phase 0 NCT07077616 Background Jul 2025 → Dec 2027 expected glioma Biogenea Pharmaceuticals Ltd. Recruiting No outcome recorded
Phase 0 NCT00091286 Background Mar 2003 → Feb 2008 colorectal cancer Craig L Slingluff, Jr Terminated No outcome recorded
Phase 179 trials
Phase 1 NCT05544968 Background Mar 2026 → Jan 2028 expected Hodgkins lymphoma, anaplastic large cell lymphoma, diffuse large B-cell lymphoma, large-cell immunoblastic lymphoma +2 Medical College of Wisconsin Recruiting No outcome recorded
Phase 1 NCT07374029 Background Feb 2026 → Oct 2027 expected acute myeloid leukemia David Avigan Recruiting No outcome recorded
Phase 1 NCT07377435 Background Jan 2026 → Mar 2028 expected plasma cell myeloma, refractory plasma cell neoplasm David Avigan Recruiting No outcome recorded
Phase 1 NCT07027748 Background Jun 2025 → Jul 2027 expected neuroblastoma Steven DuBois, MD Recruiting No outcome recorded
Phase 1 NCT06514898 Background May 2025 → Sep 2027 expected medulloblastoma non-WNT/non-SHH group 3, medulloblastoma non-WNT/non-SHH group 4 University of Florida Recruiting No outcome recorded
Phase 1/239 trials
Phase 1/2 NCT07437963 Background Jul 2026 → Sep 2029 expected ganglioneuroblastoma, neuroblastoma National Cancer Institute (NCI) Not yet recruiting No outcome recorded
Phase 1/2 NCT06173219 Background Aug 2025 → Jul 2026 overdue neoplasm China-Japan Friendship Hospital Recruiting No outcome recorded
Phase 1/2 NCT06934538 Background Jun 2025 → Jun 2028 expected colorectal cancer Brenus Pharma Recruiting No outcome recorded
Phase 1/2 NCT05269381 Background Mar 2022 → Mar 2028 expected breast adenocarcinoma, carcinosarcoma of the corpus uteri, cervical carcinoma, cutaneous melanoma +16 Mayo Clinic Recruiting No outcome recorded
Phase 1/2 NCT04929652 Background Jun 2021 → Jun 2022 colorectal cancer Jiangsu Cancer Institute & Hospital Unknown No outcome recorded
Phase 2128 trials
Phase 2 NCT05479045 Background Sep 2026 → Nov 2027 expected ovarian carcinoma, uterine adnexa cancer Georgetown University Not yet recruiting No outcome recorded
Phase 2 NCT06202066 Background Jul 2026 → Oct 2027 expected cancer, lung neuroendocrine neoplasm, pancreatic neuroendocrine neoplasm Roswell Park Cancer Institute Recruiting No outcome recorded
Phase 2 NCT07169617 Background Jul 2026 → Mar 2029 expected lung carcinoma National Cancer Institute (NCI) Not yet recruiting No outcome recorded
Phase 2 NCT07537400 Background May 2026 → Jun 2028 expected neuroblastoma Shaare Zedek Medical Center Not yet recruiting No outcome recorded
Phase 2 NCT07078604 Background Mar 2026 → Apr 2027 expected female breast carcinoma, triple-negative breast carcinoma University of Washington Recruiting No outcome recorded
Show all 128 trials opens the full record — a long page
Phase 2/32 trials
Phase 2/3 NCT00630565 Background Jul 2006 → Jul 2022 leukemia Masonic Cancer Center, University of Minnesota Terminated No outcome recorded
Phase 2/3 NCT00090493 Background Jun 2004 → Jul 2007 plasma cell myeloma University of Arkansas Completed No outcome recorded
Phase 330 trials
Phase 3 NCT05266001 Comparator Jun 2022 → Sep 2025 multiple organ dysfunction syndrome Nationwide Children's Hospital Completed No outcome recorded
Phase 3 NCT04229979 Background Feb 2021 → Dec 2025 overdue acute myeloid leukemia Sellas Life Sciences Group Active not recruiting No outcome recorded
Phase 3 NCT03126916 Background May 2018 → Sep 2030 expected neuroblastoma, nodular ganglioneuroblastoma Children's Oncology Group Recruiting No outcome recorded
Phase 3 NCT01875653 Background Oct 2014 → Jan 2016 melanoma Lisata Therapeutics, Inc. Terminated No outcome recorded
Phase 3 NCT01480479 Background Nov 2011 → Nov 2016 giant cell glioblastoma, gliosarcoma, mixed astrocytoma-ependymoma-oligodendroglioma Celldex Therapeutics Completed No outcome recorded
Phase 42 trials
Phase 4 NCT06047535 Background Oct 2023 → Jun 2027 expected neuroblastoma SciClone Pharmaceuticals Not yet recruiting No outcome recorded
Phase 4 NCT04326920 Comparator Mar → Sep 2020 COVID-19 University Hospital, Ghent Completed No outcome recorded
Phase not applicable7 trials
NCT02786719 Background Jun 2016 → Feb 2019 neuroblastoma Baylor College of Medicine Completed No outcome recorded
NCT01828762 Background Dec 2012 → Dec 2013 hepatocellular carcinoma Shanghai AbelZeta Ltd. Completed No outcome recorded
NCT01374711 Comparator May → Nov 2011 infectious disease with sepsis, multiple organ dysfunction syndrome Radboud University Medical Center Completed No outcome recorded
NCT00665002 Background Jun 2008 → Jul 2013 leukemia H. Lee Moffitt Cancer Center and Research Institute Completed No outcome recorded
NCT00912574 Comparator Jun 2004 → Jul 2008 melanoma University of Virginia Completed No outcome recorded

Evidence & citations 36 cited values

Every value below carries the sentence it was read from. 601 sources stand behind the page.

FieldValueCited text
Known as Sargramostim “Preliminary preclinical results demonstrated that GM-CSF (Granulocyte macrophage colony-stimulating factor, e.g. Leukine®/Sargramostim) rapidly reduced cerebral amyloid...” NCT01409915
341

“Subcutaneous aldesleukin (300,000IU/m2/day) and Sargramostim (250 ug/m2 twice per week) both starting 3 days before the 1st infusion and ending 7 days after the last dose of armed ATC.” NCT01081808

“Subjects will receive GM-CSF 500μg (Sargramostim (Leukine), Sanofi Aventis) by a self-administered subcutaneous injection thrice weekly on Monday, Wednesday, and Friday for four weeks” NCT01041417

“At the same time that patients get the SurVaxM/Montanide ISA 51 injection, they will also get a second subcutaneous injection of a medicine called sargramostim.” NCT04978727

“A Study of Sargramostim Plus Pembrolizumab with or Without Pemetrexed in Patients with Advance Non-small Cell Lung Cancer After Completion of Chemoimmunotherapy” NCT04856176

“Immunologic and Antibody Responses in Patients Receiving GM-CSF, (Leukine, Sargramostim) as Adjuvant Therapy of Stage II (T4), III and IV Melanoma.” NCT00350597

“Multicenter Phase II Trial of High-Dose Interleukin (IL-2) With Priming and Concomitant Sargramostim (GM-CSF) in Patients With Advanced Melanoma” NCT00616564

Sargramostim (Leukomax®, Leukine®); yeast-derived, recombinant human granulocyte-macrophage colony stimulating factor (rhu GM-CSF)” NCT05366062

“autologous dendritic cell mobilization with filgrastim (G-CSF) and/or sargramostim (GM-CSF) subcutaneously daily for 4 days” NCT00088985

“Participants will receive inhaled rhGM-CSF (Sargramostim, Leukine) at the dose of 250 mcg one time per week for 12 weeks.” NCT01511068

“All patients will receive Sargramostim (GM-CSF) (70 mcg) injected subcutaneously on days 0 and -2 of each vaccination.” NCT01265433

“GM-CSF (granulocyte-macrophage colony stimulating factor, also called sargramostim, GM, or Leukine), a growth factor” NCT00208975

“Recombinant human GM-CSF (Sargramostim) was administered at 100mcg/day on days 1-4 following each vaccine.” NCT00060528

“Drug Information: Sargramostim (Leukine) Formulation: 250 mcg, 500 mcg lyophlized powder for injection” NCT00228813

“vaccination with TARP peptides in Montanide ISA 51 VG adjuvant plus Sargramostim will be studied” NCT00972309

Sargramostim will be administered at 250 micrograms/m2/d by subcutaneous (SC) injection” NCT02169609

Sargramostim (GM-CSF), lyophilized 250 µg single use vial (250 µg/vial)” NCT04560166

“GM-CSF (Sargramostim) was co administered with each vaccine dose.” NCT00488592

“CDX-110 with sargramostim (GM-CSF) (Leukine®)” NCT01480479

“CDX-110 with sargramostim (GM-CSF) (Leukine®)” NCT00458601

sargramostim (GM-CSF) SC on days 1-10” NCT00090870

“GM-CSF (also called sargramostim)” NCT02100930

“Leukine (Sargramostim, GM-CSF)” NCT01653665

“GM-CSF: Sargramostim (Leukine)” NCT01342224

“GM-CSF (Sargramostim)” NCT00433745

sargramostim (GM-CSF)” NCT00091286

NCT03126916

NCT00085423

NCT00005601

NCT02339571

NCT00003961

NCT00118313

NCT00640861

NCT00003362

NCT04211675

NCT04040231

NCT00003093

NCT00313482

NCT00501644

NCT00003972

NCT00017121

NCT00003222

NCT00009958

NCT00450619

NCT00049517

NCT04707664

NCT00048893

NCT01334515

NCT00002995

NCT00085579

NCT00025363

NCT00003959

NCT07437963

NCT00003269

NCT00003958

NCT00005610

NCT00400517

NCT00026312

NCT00450463

NCT01250470

NCT00003181

NCT05101356

NCT00381875

NCT00002070

NCT00005630

NCT00003397

NCT00002787

NCT00521014

NCT00477815

NCT00425477

NCT00005576

NCT00003002

NCT00003003

NCT00000711

NCT00524277

NCT00027807

NCT00003955

NCT00027911

NCT00450307

NCT00050531

NCT03063242

NCT00006243

NCT00791037

NCT00027937

NCT00256282

NCT00425360

NCT00000850

NCT00002461

NCT00006240

NCT00002697

NCT00278122

NCT00017290

NCT00002560

NCT04382664

NCT00003408

NCT00309894

NCT05677633

NCT00466726

NCT00002780

NCT02240537

NCT00047021

NCT00017368

NCT00003007

NCT00046930

NCT00002778

NCT00052351

NCT00466960

NCT00157573

NCT00005787

NCT03794349

NCT00028496

NCT05269381

NCT00001090

NCT00363649

NCT02250014

NCT00053131

NCT00004162

NCT00023777

NCT05242965

NCT01479244

NCT00108732

NCT00003119

NCT00602706

NCT00002552

NCT06528496

NCT04326920

NCT00053157

NCT00893477

NCT00002773

NCT00462605

NCT04703426

NCT03012100

NCT00002594

NCT01158118

NCT00079157

NCT00016042

NCT04902703

NCT02444546

NCT00045227

NCT00030056

NCT00012376

NCT00008398

NCT02361528

NCT04400929

NCT00643097

NCT00939510

NCT00630565

NCT00030342

NCT00088413

NCT05455658

NCT00000694

NCT00002598

NCT00003185

NCT00258336

NCT00003315

NCT01826864

NCT00022230

NCT00448201

NCT01222221

NCT00562328

NCT00002766

NCT01767194

NCT06626516

NCT00002599

NCT00003163

NCT00389818

NCT00179309

NCT00002475

NCT00031733

NCT04642950

NCT02835742

NCT00308087

NCT00000689

NCT02636582

NCT00053989

NCT03790670

NCT00004184

NCT03879694

NCT06202066

NCT00088933

NCT00803569

NCT05482334

NCT01324063

NCT02667496

NCT04197687

NCT00005023

NCT00003490

NCT00003125

NCT00089063

NCT00089115

NCT02520102

NCT00089193

NCT00343109

NCT00004197

NCT00089206

NCT00006385

NCT02276300

NCT01673217

NCT00004198

NCT00089258

NCT01989572

NCT00266110

NCT02593123

NCT00003274

NCT00546377

NCT00019890

NCT00014092

NCT00242996

NCT05284214

NCT00265915

NCT00008008

NCT00019383

NCT00007995

NCT02601365

NCT02703714

NCT03332667

NCT00000681

NCT01134614

NCT00033644

NCT00002009

NCT02455557

NCT00002008

NCT00398138

NCT00014573

NCT00002950

NCT00689143

NCT00669734

NCT00206596

NCT07085338

NCT00020254

NCT04385277

NCT07027748

NCT00002007

NCT00206661

NCT00454168

NCT00652860

NCT00002006

NCT00006113

NCT00206674

NCT00019331

NCT00000896

NCT00206700

NCT07169617

NCT00001827

NCT00568763

NCT00206713

NCT00014560

NCT00673179

NCT01355393

NCT00621036

NCT00669318

NCT00305669

NCT04013672

NCT00073931

NCT00908141

NCT04237623

NCT00329537

NCT00301951

NCT00012246

NCT00569296

NCT00896519

NCT00004918

NCT00295165

NCT00262808

NCT00019097

NCT00072579

NCT00002664

NCT00002817

NCT00002263

NCT00381004

NCT00011934

NCT00004217

NCT00071981

NCT00000989

NCT00005948

NCT00104819

NCT00019084

NCT03006146

NCT00091052

NCT02780401

NCT00040937

NCT04411680

NCT00237575

NCT00071955

NCT00002809

NCT00436254

NCT01536054

NCT00040872

NCT00323557

NCT00000658

NCT00103142

NCT00037037

NCT00003561

NCT00436761

NCT00004256

NCT00006747

NCT01871467

NCT00436930

NCT00014508

NCT00005962

NCT00304018

NCT02873819

NCT00003567

NCT00004024

NCT00006478

NCT02470559

NCT00091273

NCT00324831

NCT00069940

NCT00004029

NCT00070070

NCT00411086

NCT00901511

NCT02840708

NCT07078604

NCT00064129

NCT00003199

NCT00004036

NCT00003184

NCT01882010

NCT00005987

NCT05366283

NCT00002638

NCT01041638

NCT00006483

NCT02786719

NCT00293462

NCT00514215

NCT00003727

NCT00513578

NCT00113984

NCT00006669

NCT00003897

NCT00217373

NCT02484443

NCT02334865

NCT01700673

NCT00899821

NCT00002514

NCT00066794

NCT00066365

NCT02620865

Known as Aerosol Sargramostim ClinicalTrials.gov intervention name — accepted as the source's own label NCT05717140
Known as GM-CSF “The purpose of this study is to determine safety and anti-tumor immune activation generated by TG02 and Granulocyte macrophage colony stimulating factor (GM-CSF), first as...” NCT02933944
335

“OBJECTIVES: I. Determine the one year event-free survival in patients with chronic phase chronic myeloid leukemia receiving sargramostim (GM-CSF)-treated autologous bone marrow...” NCT00011934

“Patients receive dexamethasone orally or IV on days 1-4, cisplatin IV continuously for 24 hours on day 1, cytarabine IV over 3 hours every 12 hours for 2 doses on day 2, and...” NCT00005601

“The purpose of this study was to evaluate the feasibility of hypofractionated intensity-modulated radiation therapy (IMRT), temozolomide and granulocyte-macrophage...” PMID 40090128 Mar 2025

“Here, we tested our hypothesis that modulation of the innate immune system might similarly be used to treat AD in humans by investigating the ability of GM-CSF/sargramostim to...” PMID 33778150 Mar 2021

“Patients receive rituximab IV on days 4, 11, 18, and 25 and sargramostim (GM-CSF) subcutaneously on days 1, 3, 5, 8, 10, 12, 15, 17, 19, 22, 24, 26, 29, 31, 33, 36, 38, 40, 43,...” NCT00265915

“OBJECTIVES: I. Determine the therapeutic effects of aerosolized sargramostim (GM-CSF) in terms of progression free survival at 2 months and median survival rate in patients...” NCT00005610

“This treatment will combine peritumoral injection of IL-2, IFN-α and GM-CSF (6000 IU, 100.000 IU and 300 ng per tumor injected, respectively), as well as topical application of...” NCT01191034

“multiple peptide cocktail including LY6K and vascular endothelial growth factor receptor 1 (VEGFR1) and vascular endothelial growth factor receptor 2 (VEGFR2) together with IFA...” NCT00561275

“Personalized anti-tumor neoantigen injection (300 μg/peptide) plus GM-CSF (40 μg per injection site) will be administered via subcutaneous injection at multiple sites (around...” NCT07504484

“Naxitamab and Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) Combined With Isotretinoin for Maintenance Treatment of Patients With High-Risk Neuroblastoma in First...” NCT06047535

“Evaluate the effect of ketoconazole, hydrocortisone, and sargramostim (GM-CSF) on time to clinical progression in patients with prostate cancer that has progressed on primary...” NCT00309894

“Sargramostim (GM-CSF) and rituximab: Beginning approximately 7-10 weeks (49-70 days) after ASCT, patients receive GM-CSF SC 3 times a week for 8 weeks and rituximab IV once...” NCT00521014

“Patients also receive sargramostim (GM-CSF) subcutaneously (SC) alone on days 3-9 and GM-CSF and filgrastim (G-CSF) SC beginning on day 10 and continuing until leukapheresis is...” NCT00027937

“Patients receive high-dose sargramostim (GM-CSF) subcutaneously (SC) beginning on day 5 and continuing until blood counts recover and then low-dose GM-CSF SC continuing until day 60.” NCT00002778

“TAMAVAQ Vaccine plus Poly-ICLC, cGAMP, Granulocyte-macrophage colony stimulating factor (GM-CSF), imiquimod, CpG oligodeoxynucleotides, saponins and monophosphoryl lipid A (MPLA)” NCT07077616

GM-CSF, sargramostim 250 μg/m\^2 subcutaneous injection daily on days 1 to 14 in a 28-day cycle until disease progression or unacceptable toxicity for a median of 3 cycles.” NCT00157573

“Sargramostim (GM-CSF) is initiated subcutaneously 1 day later and is continued for 10 days to support stem cell collections, which begin 10-14 days after CTX induction.” NCT00003007

“We plan to determine whether using granulocyte-macrophage colony stimulating factor (GM-CSF) in this group would increase dose-intensity and ameliorate myelotoxicity.” NCT00001237

“In a separate trial, GMCSF was used in breast cancer patients treated with adriamycin based chemotherapy as the preferred growth factor in a neoadjuvant setting (16).” NCT00256243

“Patients are vaccinated with irradiated, autologous tumor cells plus sargramostim (GM-CSF) intradermally near draining lymph nodes in the groin or axillary regions.” NCT00003185

“E75 peptide acetate (HER2/neu p366-379) in WFI (1.5 mg/mL) mixed with 250 micrograms Leukine® (sargramostim, GM-CSF), will be administered in intradermal injections” NCT01479244

“STC-1010 administered with immunostimulants (IS) in low-dose (cyclophosphamide and GM-CSF) and standard of care (SOC) therapy (mFOLFOX6 with or without bevacizumab)” NCT06934538

“Colorectal antigen 17-1A murine monoclonal antibody, MOAB 17-1A, NSC-377963; Granulocyte-macrophage colony stimulating factor (Immunex), GM-CSF, NSC-613795.” NCT00002664

“AMENDED: To evaluate the effect of sargramostim ( GM-CSF ) on modulating the granulocytopenia associated with concomitant DHPG and AZT therapy ( Phase B )” NCT00000989

“granulocyte-macrophage colony-stimulating factor (GM-CSF, sargramostim) administered subcutaneously to patients with pulmonary alveolar proteinosis (PAP).” NCT00030056

“Sargramostim (granulocyte-macrophage colony-stimulating factor; GM-CSF) is administered by subcutaneous injection on days 1-5 each week for 9 weeks.” NCT00003181

“Immunologic and Antibody Responses in Patients Receiving GM-CSF, (Leukine, Sargramostim) as Adjuvant Therapy of Stage II (T4), III and IV Melanoma.” NCT00350597

“Patients receive sargramostim (GM-CSF) subcutaneously (SC) on days 1-14 and low-dose interleukin-2 (IL-2) SC on days 1-5, 8-12, 15-19, and 22-26.” NCT00085579

“Multicenter Phase II Trial of High-Dose Interleukin (IL-2) With Priming and Concomitant Sargramostim (GM-CSF) in Patients With Advanced Melanoma” NCT00616564

“Patients also receive sargramostim (GM-CSF) subcutaneously once daily beginning 2 days before every vaccination and continuing for 5 days.” NCT00027911

“adding sargramostim (recombinant granulocyte-macrophage colony stimulating factor; GM-CSF) to a standard chemotherapy drug combination” NCT00000689

“Patients receive sargramostim (GM-CSF) subcutaneously (SC) once daily beginning between days -16 and -12 and continuing until day -1.” NCT00262808

“100 micrograms (mcg) granulocyte-macrophage colony-stimulating factor (GM-CSF) and 1 milliliter (mL) of Montanide ISA-51 adjuvant.” NCT05479045

“At the time of vaccine administration, one vial of frozen suspended peptide is thawed and mixed with 250mcg GM-CSF in the syringe.” NCT02019524

“Each dose of DC-TC contains approximately 10-20 million cells. Each dose is suspended in 500 mcg GM-CSF prior to administration.” NCT01875653

“Patients receive sargramostim (GM-CSF) IV or subcutaneously daily beginning on day 7 and continuing until blood counts recover.” NCT00006747

“Patients receive sargramostim (GM-CSF) subcutaneously once daily beginning on day 6 and continuing until blood counts recover.” NCT00602706

“Patients receive sargramostim (GM-CSF) subcutaneously (SC) once daily on days 1-5 (or G-CSF twice daily alone for 4-5 days).” NCT00003567

“autologous dendritic cell mobilization with filgrastim (G-CSF) and/or sargramostim (GM-CSF) subcutaneously daily for 4 days” NCT00088985

“Patients also receive an intratumoral injection of sargramostim (GM-CSF) to promote further ablation at the tumor site.” NCT00568763

“Sargramostim (GM-CSF) is administered subcutaneously (SC) beginning on day 1 and continuing until blood counts recover.” NCT00019097

“All patients will receive Sargramostim (GM-CSF) (70 mcg) injected subcutaneously on days 0 and -2 of each vaccination.” NCT01265433

“AV-MEL-1 is admixed with granulocyte-macrophage colony stimulating factor (GM-CSF) as an adjuvant, prior to injection.” NCT03743298

“daily neoadjuvant sargramostim (GM-CSF) in patients with localized prostate cancer undergoing radical prostatectomy.” NCT00305669

“the use of sargramostim (granulocyte-macrophage colony-stimulating factor; GM-CSF) will improve bone marrow function” NCT00000658

“Each DRibble vaccine will be followed by the 6-day infusion of GM-CSF via the CADD-MS 3 pump (50 micrograms/24 hrs).” NCT00850785

“Patients receive sargramostim (GM-CSF) SC daily beginning 1 day prior to the vaccination and continuing for 4 days.” NCT00019331

“Patients receive sargramostim (GM-CSF) SC once daily beginning on day 6 and continuing until blood counts recover.” NCT00242996

“granulocyte-monocyte colony-stimulating factor (GM-CSF) induces follicular lymphoma (FL)-specific immune responses” PMID 21632504 May 2011

“Patients receive treatment as in arm I followed by sargramostim (GM-CSF) SQ for 5 days after each vaccination.” NCT00003274

“The DC vaccine is given on Day 1 of the DCV cycle plus low-dose GM-CSF 50mcg/day SQ x 5 days (Day 1 to Day 4).” NCT02705703

“Patients also receive sargramostim (GM-CSF) SC on days 1-4 of the same weeks as the Id-KLH conjugate vaccine.” NCT00621036

“using granulocyte-macrophage colony-stimulating factor (GM-CSF) to ameliorate chemotherapy-induced toxicity.” NCT00001239

“Patients receive paclitaxel IV over 3 hours on day 1 and sargramostim (GM-CSF) subcutaneously on days 4-17.” NCT00278122

“Patients with malignant gliomas will receive combined immune adjuvants (GM-CSF, TLR ligands) and radiation.” NCT03392545

“Hydrogel combining TLR or NOD2 agonist and GM-CSF will be injected in 1, 2 or 3 distinct lesions after RFA.” NCT04062721

GM-CSF: 4 x 40 mcg (total dose 160 mcg) given on days 1, 4, 8, 15, 22, 78, and 162 for a total of 7 doses” NCT03645148

“Patients also receive sargramostim (GM-CSF) SC immediately after vaccination and once daily on days 1-4.” NCT00381875

“multi-epitope melanoma peptides (MP), tetanus toxoid helper peptide (TET), and sargramostim (GM-CSF)” NCT00118313

“Sargramostim (GM-CSF) subcutaneously beginning on day 14 and continuing until blood counts recover.” NCT00047021

“sargramostim (GM-CSF) intratumorally continuously for 1 week and then subcutaneously for 2 weeks” NCT00091052

“Patients received GM-CSF at 250 mcg/m(2) subcutaneously for 14 days followed by 14 days of rest.” PMID 23210004 Jul 2011

“Granulocyte macrophage colony stimulating factor (GM-CSF) when given in addition to gemcitabine” NCT02261714

“Patients receive aerosolized sargramostim (GM-CSF) by nebulizer over 10-15 minutes twice daily” NCT00006483

“glioblastoma multiform multi-antigen vaccine IMA950 plus sargramostim (GM-CSF) in combination” NCT01222221

“Sargramostim (GM-CSF) is administered subcutaneously on days 5-14 until blood counts recover.” NCT00004162

“Patients also receive sargramostim (GM-CSF) SC on days 1-5 of weeks 0, 26, 52, 78, and 104.” NCT00089063

GM-CSF (250μg) will be administered to promote attraction, maturation and longevity of DCs.” NCT00090493

“CDX-1307 vaccine co-administered with immune adjuvants (GM-CSF, Poly-ICLC and Resiquimod)” NCT01094496

“Patients receive subcutaneous injections of sargramostim (GM-CSF) once a day for 5 days.” NCT00003490

“a laboratory-made agent called Granulocyte Macrophage Colony Stimulating Factor (GM-CSF)” NCT00458536

“Patients receive PR1 leukemia peptide vaccine and sargramostim (GM-CSF) subcutaneously.” NCT00454168

“Patients receive oral bexarotene and sargramostim (GM-CSF) subcutaneously on days 1-28.” NCT00425477

“subcutaneous sargramostim ( granulocyte-macrophage colony-stimulating factor; GM-CSF )” NCT00002263

“sargramostim ( recombinant granulocyte-macrophage colony-stimulating factor; GM-CSF )” NCT00002007

“Patients receive CAP 1-6D dissolved in sargramostim (GM-CSF) intradermally on day 1.” NCT00012246

GM-CSF, or sargramostim, is a protein that acts as a white blood cell growth factor.” NCT05101356

“sargramostim (GM-CSF) SC beginning on day 3 and continuing until PBSC are harvested” NCT00017368

“Patients receive sargramostim (GM-CSF) subcutaneously once daily on days -5 to 11.” NCT00089258

“Patients also receive sargramostim (GM-CSF) subcutaneously (SC) three times a week” NCT00008398

“granulocyte macrophage stimulating factor (GM-CSF), high-dose hepatitis B vaccine” NCT05451420

“MUC-1 vaccine (100ug) admixed with GM-CSF (100ug), administered subcutaneously” NCT00374049

“then were treated with 75 μg of GM-CSF subcutaneously at day 2, 3, 4, 5 and 6” NCT01878565

“Patients receive sargramostim (GM-CSF) subcutaneously (SC) on days 1 and 2” NCT00466726

“patients are treated with sargramostim (GM-CSF) intravenously over 4 hours” NCT00003003

“Second, the patient will be vaccinated twice with those cells and GM-CSF.” NCT01081223

“Patients receive sargramostim (GM-CSF) subcutaneously daily for 3 months” NCT00072579

“Patients receive sargramostim (GM-CSF) subcutaneously (SC) on days 1-14.” NCT00908141

“granulocyte macrophage colony-stimulating factor (GM-CSF) (sargramostim)” NCT01989572

“Recombinant Idiotype Conjugated to KLH (Id-KLH) Administered With GM-CSFNCT00302861

“sargramostim (GM-CSF; granulocyte-macrophage colony stimulating factor)” NCT00000681

“sargramostim (granulocyte-macrophage colony-stimulating factor; GM-CSF)” NCT00002070

“Sargramostim (GM-CSF), lyophilized 250 µg single use vial (250 µg/vial)” NCT04560166

“Adjuvants: 75 microgram GM-CSF + 1 application Imiquimod every 2nd week” NCT01543464

“Subcutaneous Granulocyte Macrophage Colony Stimulating Factor (GM-CSF)” NCT00969722

“granulocyte macrophage colony-stimulating factor (GM-CSF) ± montanide.” PMID 24520093 Feb 2014

“systemic treatment with PEG-IFN alfa and GM-CSF to potentiate activity” NCT00610389

“Patients receive sargramostim (GM-CSF) subcutaneously on days 5-60.” NCT00003961

“0.5 mg of idiotype conjugated to 0.5 mg of KLH + 125 mcg of GM-CSFNCT00530140

“sargramostim (GM-CSF) SC into the same injection site once daily” NCT00103142

“sargramostim (GM-CSF) subcutaneously once daily on days -5 to 11” NCT00450307

“Sargramostim (GM-CSF) will be given on day 8-17 at 250 mcg/m\^2” NCT03332667

“sargramostim (GM-CSF) SC twice in weeks 0, 4, 6, 8, 10, and 12” NCT00398138

“All patients receive sargramostim (GM-CSF) beginning on day 4.” NCT00003269

“Patients also receive sargramostim (GM-CSF) SC on days 1-4.” NCT00089115

“Patients also receive sargramostim (GM-CSF) SC on days 1-4.” NCT00104819

“sargramostim (GM-CSF) subcutaneously on days 1-7 and 15-21” NCT00006240

“Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)” NCT01592045

“Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF)” NCT01363206

“Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)” NCT01555580

“Granulocyte Macrophage Colony Stimulating Factor (GM-CSF)” NCT02709993

“Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF)” NCT07537400

“During the TI, patients received sc GM-CSF (250 mcg TIW)” NCT00979706

GM-CSF hematopoietic growth factor will start on Day 0.” NCT01049854

“Sargramostim (GM-CSF) SC is administered on days 1-4.” NCT00006478

“Patients receive oral sargramostim (GM-CSF) mouthwash” NCT00293462

“sargramostim (GM-CSF) subcutaneously (SC) on days 1-5” NCT00016042

“stereotactic radiosurgery and GM-CSF, Sapylin, MnCl2” NCT05131711

“sargramostim (GM-CSF) subcutaneously on days 5-21” NCT00002780

“4B5 in sargramostim (GM-CSF) subcutaneously (SQ)” NCT00004184

“sargramostim (GM-CSF) intradermally on days 1-10” NCT00003959

“sargramostim (GM-CSF) SC on days 1-4 of week 1” NCT00052351

“CDX-110 with sargramostim (GM-CSF) (Leukine®)” NCT00458601

“followed by sargramostim (GM-CSF) SQ on day 1” NCT00004198

“sargramostim (GM-CSF) SC daily on days 1-4” NCT00020254

“sargramostim (GM-CSF) subcutaneously (SC)” NCT00003125

“with sargramostim (GM-CSF) as an adjuvant” NCT00003002

GM-CSF, 200ug/QD, subcutaneous injection” NCT06173219

“ESR1 peptides plus Montanide and GM-CSFNCT04270149

“sargramostim (GM-CSF) IV over 2 hours” NCT00002560

“sargramostim (GM-CSF) subcutaneously” NCT00014560

“sargramostim (GM-CSF) subcutaneously” NCT00002552

“sargramostim (GM-CSF) SC on days 1-4” NCT00045227

“sargramostim (GM-CSF) SC on days 1-4” NCT00069940

“500 mcg/mL GP2 and 125 mcg/mL GM-CSFNCT05232916

“the cytokine sargramostim (GM-CSF)” NCT00003315

“adjuvant sargramostim (GM-CSF) SC” NCT00017290

“sargramostim (GM-CSF) as adjuvant” NCT00003362

GM-CSF (Sargramostim, Leukine®)” NCT00896519

“Leukine (Sargramostim, GM-CSF)” NCT01653665

“adjuvant sargramostim (GM-CSF)” NCT00005023

“Sargramostim (GM-CSF, Leukine)” NCT00088413

“cDNA for sargramostim (GM-CSF)” NCT00003897

“sargramostim (GM-CSF) SQ” NCT00019383

“sargramostim \[GM-CSF\]” NCT00899821

GM-CSF (Sargramostim)” NCT00433745

“sargramostim (GM-CSF)” NCT00006113

“sargramostim (GM-CSF)” NCT00037037

“sargramostim (GM-CSF)” NCT00091273

“sargramostim (GM-CSF)” NCT00089206

“sargramostim (GM-CSF)” NCT00091286

“sargramostim (GM-CSF)” NCT00436930

GM-CSF (sargramostim)” NCT00524277

“sargramostim (GM-CSF)” NCT00079157

“sargramostim (GM-CSF)” NCT00258336

“sargramostim (GM-CSF)” NCT00030342

“Sargramostim (GM-CSF)” NCT04703426

“Sargramostim (GM-CSF)” NCT00477815

“sargramostim (GM-CSF)” NCT00003408

“sargramostim (GM-CSF)” NCT00003184

“sargramostim (GM-CSF)” NCT00301951

“sargramostim (GM-CSF)” NCT00014092

“sargramostim (GM-CSF)” NCT00004024

“sargramostim (GM-CSF)” NCT00005630

“sargramostim (GM-CSF)” NCT00640861

“125 µg GM-CSF s.c.” NCT01022255

GM-CSF: 40 mcg” NCT04810910

“Drug: GM CSF” NCT00274287

“Drug: GM-CSFNCT01542684

GM-CSFNCT01536054

NCT03761914

NCT05760196

NCT03014076

NCT02173093

NCT00204516

NCT00678054

NCT03927222

NCT03630211

NCT00257322

NCT04106180

NCT01909752

NCT00769704

NCT03426995

NCT02978222

NCT06345599

NCT01784913

NCT00880243

NCT04979832

NCT01580696

NCT02250768

NCT04501757

NCT00646763

NCT04713371

NCT00470015

NCT00272493

NCT00940342

NCT00450008

NCT00582725

NCT05266001

NCT03304821

NCT00477087

NCT06450041

NCT00429104

NCT00256243

NCT00001564

NCT01374711

NCT00005780

NCT04861948

NCT02243228

NCT02933333

NCT04909515

NCT00854789

NCT01130376

NCT02275416

NCT06651853

NCT06989333

NCT04936529

NCT03033303

NCT01403285

NCT01627678

NCT00631072

NCT01903330

NCT02130869

NCT03615404

NCT01174082

NCT03222089

NCT00834665

NCT00111397

NCT00001561

NCT02677155

NCT03559413

NCT00499343

NCT05530200

NCT01232504

NCT01857934

NCT04929652

NCT00841399

NCT00448409

NCT00505921

NCT03396575

NCT02451488

NCT05115500

NCT01827137

NCT02078648

NCT04963413

NCT00204607

NCT01789099

NCT00001512

NCT02411786

NCT00447473

NCT00548847

NCT05238558

NCT03982004

NCT01176552

NCT01939730

NCT04100655

NCT00600002

NCT01498328

NCT01828762

NCT06438614

NCT00254592

NCT00089219

NCT04229979

NCT00383994

NCT00076037

NCT00661622

NCT01322490

NCT06013618

NCT02502786

NCT03363373

NCT02641782

NCT02297698

NCT02149225

NCT00446173

NCT00799110

NCT01530984

NCT03538314

NCT02009397

NCT03282188

NCT00948480

NCT06254326

NCT01266083

NCT00912418

NCT00252915

NCT02383212

NCT03600350

NCT00488592

NCT01757626

NCT00201409

NCT01480479

NCT05603013

NCT02728102

NCT01265901

NCT02465268

NCT06112041

NCT02100930

NCT04238819

NCT00090870

NCT05292417

NCT02223312

NCT03316651

NCT03782064

NCT01570036

NCT03334305

NCT07374029

NCT00533923

NCT05544968

NCT06514898

NCT07377435

NCT04739618

NCT03189706

NCT06799026

NCT01064375

NCT00488982

NCT07327411

NCT01715974

NCT01183884

NCT01183897

NCT00912574

NCT04892498

NCT00952237

NCT02774421

NCT01495637

NCT05307835

NCT00415857

NCT00471471

NCT01718210

NCT00455221

NCT03769844

NCT06472739

NCT03023111

NCT00512889

NCT00208949

NCT00208975

NCT00455897

Known as GM-CSF (sargramostim) GM-CSF (sargramostim)NCT00524277
2

GM-CSF (Sargramostim)NCT02019524

GM-CSF (sargramostim)NCT01580696

Known as GM-CSF = Leukine GM-CSF = LeukineNCT01627678
Known as GM-CSF: molgramostim GM-CSF: molgramostimNCT00880243
Known as GMCSF (granulocyte macrophage colony stimulating factor) ClinicalTrials.gov intervention name — accepted as the source's own label NCT00006184
Known as granulocyte and macrophage colony-stimulating factor “topical granulocyte and macrophage colony-stimulating factor (GM-CSF) and miltefosine (G + M) versus placebo and miltefosine (P + M)” PMID 33253864 Nov 2020
Known as Granulocyte Macrophage Colony Stimulation Factor ClinicalTrials.gov intervention name — accepted as the source's own label NCT04408092
Known as granulocyte macrophage colony- stimulating factor (GM-CSF) granulocyte macrophage colony- stimulating factor (GM-CSF)NCT00488592
3

“Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF)” NCT07537400

NCT02452307

NCT01368276

Known as granulocyte-macrophage colony-stimulating factor “The purpose of this study is to determine safety and anti-tumor immune activation generated by TG02 and Granulocyte macrophage colony stimulating factor (GM-CSF), first as...” NCT02933944
74

“Through compassionate use, 4 patients with progression of disease or refractory disease after HITS therapy, have been further treated with two cycles of a combination of...” NCT06438614

“The primary goal of this study is to determine the effects (good and bad) of Granulocyte-macrophage colony stimulating factor (GM-CSF) in combination with Cytoxan, Adriamycin,...” NCT00455897

“We aimed to investigate the safety of intraperitoneal administration of the combination of fosfomycin, metronidazole, and recombinant human granulocyte-macrophage...” PMID 31040341 Apr 2019

“Although IFN-γ and granulocyte-macrophage colony-stimulating factor (GM-CSF) restore immune competence of ex vivo stimulated leukocytes of patients with sepsis, effects on...” PMID 22822024 Jul 2012

Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a naturally occurring substance that is made by the body in response to infection or inflammation, and greatly...” NCT00272493

“Their phase 1-2 trials revealed that the E75 + granulocyte-macrophage colony-stimulating factor (GM-CSF) vaccine is safe and effective in stimulating clonal expansion of...” PMID 20845479 Sep 2010

“The purpose of this study is to find out if an antibody called Humanized 3F8 (Hu3F8) combined with granulocyte- macrophage colony stimulating factor (GM-CSF) is safe for...” NCT01757626

“PRaG therapy, which combines PD-1/PD-L1 inhibitors, radiotherapy, and granulocyte-macrophage colony-stimulating factor (GM-CSF), aims to treat patients with advanced, refractory tumors.” PMID 41308040 Nov 2025

“TAMAVAQ Vaccine plus Poly-ICLC, cGAMP, Granulocyte-macrophage colony stimulating factor (GM-CSF), imiquimod, CpG oligodeoxynucleotides, saponins and monophosphoryl lipid A (MPLA)” NCT07077616

“Granulocyte macrophage colony-stimulating factor (GM-CSF) was administered at a dose of 125 μg/m²/day subcutaneously for 14 days, followed by a 14-day rest period for 24 weeks.” NCT00769704

“three (3) days of subcutaneous Granulocyte Macrophage Colony Stimulating Factor (GM-CSF) to increase bone marrow production of monocytes and dendritic cell (DC) precursors” NCT02705703

“Treatment of autoimmune pulmonary alveolar proteinosis (aPAP) by inhaled granulocyte-macrophage colony stimulating factor (GM-CSF) is considered safe and effective.” PMID 32615994 Jul 2020

“Administration of Granulocyte Macrophage Colony Stimulating Factor (GM-CSF) to patients with pancreatic adenocarcinoma will result in enhance recruitment of DCs” NCT00600002

Granulocyte-macrophage colony-stimulating factor (GM-CSF) is administered at 400µg per day for 3 days starting on the first day after the end of radiotherapy.” NCT06651853

“Participants will receive SL-701 with the vaccine adjuvants granulocyte macrophage-colony stimulating factor (GM-CSF) injection and imiquimod topical cream.” NCT02078648

“Colorectal antigen 17-1A murine monoclonal antibody, MOAB 17-1A, NSC-377963; Granulocyte-macrophage colony stimulating factor (Immunex), GM-CSF, NSC-613795.” NCT00002664

granulocyte-macrophage colony-stimulating factor (GM-CSF, sargramostim) administered subcutaneously to patients with pulmonary alveolar proteinosis (PAP).” NCT00030056

“Sargramostim (granulocyte-macrophage colony-stimulating factor; GM-CSF) is administered by subcutaneous injection on days 1-5 each week for 9 weeks.” NCT00003181

“the granulocyte macrophage-colony stimulating factor (GM-CSF) for the Reversal of Immunoparalysis in Pediatric Sepsis-induced MODS (GRACE)-2 trial” PMID 37498156 Jul 2023

“The vaccine/adjuvant combination will be evaluated with or without coadministration of granulocyte-macrophage colony-stimulating factor (GM-CSF).” NCT00076037

“100 micrograms (mcg) granulocyte-macrophage colony-stimulating factor (GM-CSF) and 1 milliliter (mL) of Montanide ISA-51 adjuvant.” NCT05479045

Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a cytokine promoting leukocyte proliferation and trophoblast growth.” PMID 40965804 Sep 2025

Granulocyte-macrophage colony-stimulating factor (GM-CSF) (Leukine ®) will be used as adjuvant for 11 of the 13 doses of UV1.” NCT01789099

“Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF), Prevnar-Pneumococcal Conjugate vaccine (PCV), T cell infusion” NCT00834665

Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) during induction and consolidation courses versus no priming.” NCT00880243

“AV-MEL-1 is admixed with granulocyte-macrophage colony stimulating factor (GM-CSF) as an adjuvant, prior to injection.” NCT03743298

“the use of sargramostim (granulocyte-macrophage colony-stimulating factor; GM-CSF) will improve bone marrow function” NCT00000658

“granulocyte macrophage-colony stimulating factor (GM-CSF) or placebo conducted at three academic medical centers.” PMID 28358594 Jun 2017

“using granulocyte-macrophage colony-stimulating factor (GM-CSF) to ameliorate chemotherapy-induced toxicity.” NCT00001239

granulocyte-macrophage colony-stimulating factor (GM-CSF), interferon alpha (IFN) and interleukin-2 (IL-2)” NCT01176552

“hepatitis B immune globin (HBIG)+granulocyte-macrophage colony-stimulating factor (GM-CSF)+HBV vaccine” NCT01878565

“Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) and Humanized IgG1 monoclonal GD2 antibody” NCT03363373

“Naxitamab will be combined with granulocyte-macrophage colony stimulating factor (GM-CSF).” NCT04501757

“GM-CSF Granulocyte-Macrophage Colony-Stimulating Factor (Hoechst/Immunex), NSC-613795” NCT00001561

“Immunotherapy:Granulocyte macrophage-colony stimulating factor(GM-CSF)、Cadumilimab” NCT06345599

granulocyte-macrophage colony-stimulating factor (GM-CSF) (0.03 mg/injection)” PMID 39998682 Feb 2025

“sargramostim ( granulocyte-macrophage colony-stimulating factor; GM-CSF )” NCT00002006

“sargramostim (GM-CSF; granulocyte-macrophage colony stimulating factor)” NCT00000681

“sargramostim (granulocyte-macrophage colony-stimulating factor; GM-CSF)” NCT00002070

“subcutaneous granulocyte-macrophage colony-stimulating factor (GM-CSF)” NCT02774421

“granulocyte macrophage colony-stimulating factor (GM-CSF) ± montanide.” PMID 24520093 Feb 2014

“adjuvant GM-CSF (Granulocyte Macrophage Colony-stimulating Factor)” NCT03559413

Granulocyte-macrophage Colony-stimulating Factor (GM-CSF)” NCT00912418

“Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF)” NCT02502786

“GM-CSF (granulocyte-macrophage colony-stimulating factor)” NCT02100930

“Granulocyte Macrophage Colony Stimulating Factor (GM-CSF)” NCT02709993

“granulocyte macrophage colony-stimulating factor (GM-CSF)” NCT00948480

“Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF)” NCT06047535

“Granulocyte macrophage colony stimulating factor (GM-CSF)” NCT02261714

“GM-CSF (granulocyte-macrophage colony-stimulating factor)” NCT06989333

“granulocyte-macrophage colony stimulating factor (GM-CSF)” PMID 34526044 Sep 2021

“granulocyte-macrophage colony stimulating factor (GM-CSF)” NCT01183897

“granulocyte-macrophage colony stimulating factor” NCT04100655

“Granulocyte Macrophage Colony Stimulating Factor” NCT01232504

NCT03306589

NCT00004141

NCT04144023

NCT00429416

NCT01555580

NCT00969722

NCT02663440

NCT05754684

NCT06047860

NCT03332329

NCT02327416

NCT02332473

NCT01363206

NCT05817214

NCT00458536

NCT03164889

NCT00001237

NCT01592045

NCT02429440

NCT01408901

Known as Granulocyte-macrophage stimulating factor Granulocyte-macrophage stimulating factor (GM-CSF) increases circulating dendritic cells but does not abrogate suppression of adaptive cellular immunity” PMID 22270330 Jan 2012
1

“granulocyte macrophage stimulating factor (GM-CSF)” NCT05451420

Known as Granulocyte-Macrophage Stimulating-Colony Factor “The purpose of this study was to investigate the potential effects of Granulocyte-Macrophage Stimulating-Colony Factor (GM-CSF) supplementation in embryo culture for patients...” NCT02250768
Known as granulocyte-monocyte colony-stimulating factor granulocyte-monocyte colony-stimulating factor (GM-CSF)” PMID 21632504 May 2011
Known as GZ402664 “Sargramostim GZ402664NCT02667496
Known as IMA910 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00785122
Known as Leucomax “GM-CSF (Leucomax, recombinant human GM-CSF from Escherichia Coli, Schering Plough, Kenilworth,N.J., USA) is given at a dose of 5µg/kg per day, intravenously beginning at day 1...” NCT00880243
Known as Leukine “Interferon gamma 1b (Actimmune) and GM-CSF (Leukine) are two cytokine therapies that have been approved in the treatment of chronic granulomatous disease and...” NCT00111397
27

“E75 peptide acetate (HER2/neu p366-379) in WFI (1.5 mg/mL) mixed with 250 micrograms Leukine® (sargramostim, GM-CSF), will be administered in intradermal injections” NCT01479244

“Open-label Trial of Leukine® (Sargramostim), A Recombinant Human Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF), in Active Crohn's Disease” NCT00206700

“Immunologic and Antibody Responses in Patients Receiving GM-CSF, (Leukine, Sargramostim) as Adjuvant Therapy of Stage II (T4), III and IV Melanoma.” NCT00350597

“Sargramostim (Leukomax®, Leukine®); yeast-derived, recombinant human granulocyte-macrophage colony stimulating factor (rhu GM-CSF)” NCT05366062

“Immunologic Effects of GM-CSF (Sargramostim, Leukine®) in Patients With Biochemically-relapsed Prostate Cancer” NCT00908141

“Patients will receive hematopoietic growth factor support with either Leukine (Arm A), or Neupogen (Arm B).” NCT00237575

“Drug Information: Sargramostim (Leukine) Formulation: 250 mcg, 500 mcg lyophlized powder for injection” NCT00228813

“escalating dose of GM-CSF (Leukine) up to 250 mcg.” NCT01527422

“CDX-110 with sargramostim (GM-CSF) (Leukine®)” NCT01480479

“CDX-110 with sargramostim (GM-CSF) (Leukine®)” NCT00458601

“Sargramostim: Leukine (Genzyme USA)” NCT02361528

“GM-CSF (Sargramostim, Leukine®)” NCT00896519

“Sargramostim (GM-CSF, Leukine)” NCT00088413

“Sargramostim (GM-CSF, Leukine)” NCT00450463

Leukine (Sargramostim, GM-CSF)” NCT01653665

“Drug: Sargramostim (Leukine)” NCT00329537

“Sargramostim (Leukine)” NCT00206713

“Sargramostim (Leukine)” NCT00206674

“Sargramostim (Leukine)” NCT00206661

“Sargramostim (Leukine)” NCT00206596

“Sargramostim (Leukine)” NCT00295165

LeukineNCT00571662

NCT00523159

NCT00176280

NCT00785122

NCT01511068

NCT04300244

Known as Leukine (Sargramostim) Leukine (Sargramostim)NCT01527422
Known as Leukomax “Sargramostim (Leukomax®, Leukine®); yeast-derived, recombinant human granulocyte-macrophage colony stimulating factor (rhu GM-CSF)” NCT05366062
Known as Molgramostim “GM-CSF (Molgramostim, TOPLEUCON®; Xiamen Amoytop Biotech Co., Ltd., China)” NCT01232504
Known as NSC-613795 “Colorectal antigen 17-1A murine monoclonal antibody, MOAB 17-1A, NSC-377963; Granulocyte-macrophage colony stimulating factor (Immunex), GM-CSF, NSC-613795.” NCT00002664
1

“GM-CSF Granulocyte-Macrophage Colony-Stimulating Factor (Hoechst/Immunex), NSC-613795NCT00001561

Known as Recombinant GM-CSF ClinicalTrials.gov intervention name — accepted as the source's own label NCT00083551
Known as recombinant granulocyte-macrophage colony-stimulating factor “adding sargramostim (recombinant granulocyte-macrophage colony stimulating factor; GM-CSF) to a standard chemotherapy drug combination” NCT00000689
1

“sargramostim ( recombinant granulocyte-macrophage colony-stimulating factor; GM-CSF )” NCT00002007

Known as Recombinant human GM-CSF Recombinant human GM-CSFNCT02411786
1

NCT00060528