drugset / Trial / NCT00004036

Combination Chemotherapy Plus Amifostine in Treating Patients With Advanced Cancer

NCT00004036

Phase 1 Unknown 30 enrolled The Cleveland Clinic
Supportive care

Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop tumors from dividing so they stop growing or die. Chemoprotective drugs, such as amifostine, may protect normal cells from the side effects of chemotherapy. PURPOSE: Phase I trial to study the effectiveness of amifostine plus combination chemotherapy in treating patients with advanced cancer.

Timeline

Start
1997-11
Primary completion
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject Carboplatin Small molecule
Subject Cyclophosphamide Other / unclassified
Subject amifostine Unknown Intravenous
Subject sargramostim Protein / enzyme biologic Subcutaneous