drugset / Trial / NCT00893477

GM-CSF and Rituximab in Treating Patients With Previously Untreated Follicular Non-Hodgkin Lymphoma

NCT00893477 ↗

Phase 2 Unknown 60 enrolled French Innovative Leukemia Organisation
Non-randomizedOpen-labelTreatment

Summary

RATIONALE: Biological therapies, such as GM-CSF, may stimulate the immune system in different ways and stop cancer cells from growing. Monoclonal antibodies, such as rituximab, can block cancer growth in different ways. Some block the ability of cancer cells to grow and spread. Others find cancer cells and help kill them or carry cancer-killing substances to them. Giving GM-CSF together with rituximab may kill more cancer cells. PURPOSE: This phase II trial is studying how well giving GM-CSF together with rituximab works in treating patients with previously untreated follicular non-Hodgkin lymphoma.

Timeline

Start
2009-03
Primary completion
2011-03
Completion
—

Drugs

EvaluationDrugModalityDoseRoute
Subject Rituximab Monoclonal antibody — Intravenous
Subject sargramostim Protein / enzyme biologic — Subcutaneous

Indications