drugset / Trial / NCT00002664

Monoclonal Antibody Therapy and Colony- Stimulating Factor in Treating Patients With Metastatic Colorectal Cancer

NCT00002664 ↗

Phase 2 Withdrawn James Ahlgren
NaSingle-groupOpen-labelTreatment

Summary

RATIONALE: Monoclonal antibodies can locate tumor cells and either kill them or deliver tumor-killing substances to them without harming normal cells. Colony-stimulating factors such as G-CSF may increase the number of immune cells found in bone marrow or peripheral blood, and may help a person's immune system kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of monoclonal antibody therapy plus G-CSF in treating patients with metastatic colorectal cancer that has not responded to treatment with fluorouracil.

Timeline

Start
1995-07
Primary completion
2017-02-22
Completion
2017-02-22

Outcome

Outcome not reported

Stopped (Enrollment): “No recruitment”

Drugs

EvaluationDrugModalityDoseRoute
Subject edrecolomab Monoclonal antibody — —
Subject sargramostim Protein / enzyme biologic — —

Indications