drugset / Trial / NCT02484443

Dinutuximab in Combination With Sargramostim in Treating Patients With Recurrent Osteosarcoma

NCT02484443

Phase 2 Completed 41 enrolled National Cancer Institute (NCI)
NaSingle-groupOpen-labelTreatment

Summary

This phase II trial studies how well dinutuximab works when given with sargramostim in treating patients with osteosarcoma that has come back after treatment (recurrent). Monoclonal antibodies, such as dinutuximab, may find tumor cells and help kill them. Sargramostim may help the body increase the amount of white blood cells it produces, which help the body fight off infections. Giving dinutuximab with sargramostim may work better and kill more cancer cells.

Timeline

Start
2016-02-04
Primary completion
2020-03-31
Completion
2023-09-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Dinutuximab Monoclonal antibody Intravenous
Subject sargramostim Protein / enzyme biologic Subcutaneous