drugset / Trial / NCT01158118
Plerixafor and Sargramostim (GM-CSF) for Mobilization of Allogeneic Sibling Donors
Non-randomizedParallel-groupOpen-labelTreatment
Summary
This study will gather information about the combination the drugs plerixafor with sargramostim in donors of blood-forming cells (stem cells). These stem cells will be collected from the donor and transplanted into their sibling. The investigators believe that the two drugs together will provide enough stem cells for transplantation and may also reduce the risk of graft versus host disease.
Timeline
- Start
- 2011-04-01
- Primary completion
- 2014-01-15
- Completion
- 2016-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Plerixafor | Small molecule | 320 ug/kg | Intravenous |
| Subject | sargramostim | Protein / enzyme biologic | 5 ug/kg | — |
| Subject | sargramostim | Protein / enzyme biologic | 10 ug/kg | — |