drugset / Trial / NCT01250470

Vaccine Therapy and Sargramostim in Treating Patients With Malignant Glioma

NCT01250470

NaSingle-groupOpen-labelTreatment

Summary

This phase I trial studies the side effects of vaccine therapy when given together with sargramostim in treating patients with malignant glioma. Vaccines made from survivin peptide may help the body build an effective immune response to kill tumor cells. Colony-stimulating factors, such as sargramostim, may increase the number of white blood cells and platelets found in bone marrow or peripheral blood. Giving vaccine therapy and sargramostim may be a better treatment for malignant glioma.

Timeline

Start
2012-09-05
Primary completion
2014-05-29
Completion
2014-05-29

Drugs

EvaluationDrugModalityDoseRoute
Subject SVN53-67/M57-KLH Peptide Vaccine Vaccine Subcutaneous
Subject sargramostim Protein / enzyme biologic Subcutaneous