drugset / Trial / NCT00004029

Vaccine Therapy in Treating Patients With Metastatic Prostate Cancer

NCT00004029

Phase 1 Completed 46 enrolled National Cancer Institute (NCI)
NaSingle-groupOpen-labelTreatment

Summary

Phase I trial to study the effectiveness of vaccine therapy in treating patients with metastatic prostate cancer. Vaccines may make the body build an immune response to kill tumor cells.

Timeline

Start
1996-12
Primary completion
2006-05
Completion

Publications

  • Results Eder JP Jr, Kantoff PW, Bubley GJ, et al.: A phase I trial of recombinant prostate specific antigen expressing vaccinia virus vaccine, PROSTVAC (rV-PSA) in advanced prostate cancer. [Abstract] Proceedings of the American Society of Clinical Oncology 18: A1692, 439, 1999.
  • Results Eder JP Jr, Kantoff PW, Bubley GJ, et al.: A phase I trial of recombinant vaccinia virus, PROSTVAC that expresses prostate specific antigen (rV-PSA) as a vaccine in men with advanced prostate cancer. [Abstract] Proceedings of the American Society of Clinical Oncology 17: A1672, 434, 1998.

Drugs

EvaluationDrugModalityDoseRoute
Subject rV-PSA Vaccine
Subject sargramostim Protein / enzyme biologic Subcutaneous

Indications