drugset / Trial / NCT00002601
Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Sarcoma
NaSingle-groupOpen-labelTreatment
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug and combining chemotherapy with peripheral stem cell transplantation may allow the doctor to give higher doses of chemotherapy drugs and kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of high-dose combination chemotherapy and peripheral stem cell transplantation in treating patients who have advanced or recurrent sarcoma.
Timeline
- Start
- 1994-09
- Primary completion
- 2014-09
- Completion
- 2014-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cisplatin | Other / unclassified | 100 mg/m2 | Intravenous |
| Subject | Doxorubicin | Other / unclassified | 150 mg/m2 | Intravenous |
| Subject | Ifosfamide | Small molecule | 14000 mg/m2 | Intravenous |
| Subject | Melphalan | Small molecule | 75 mg/m2 | Intravenous |
| Background | filgrastim | Protein / enzyme biologic | 5 ug/kg | Subcutaneous |