Drugs / Ifosfamide
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Ifosfamide

Small molecule

Developed for
sarcoma · lymphoma · soft tissue sarcoma · leukemia · neuroblastoma · osteosarcoma · ovarian cancer · diffuse large B-cell lymphoma
+186 more · extragonadal germ cell tumor · testicular germ cell tumor · non-Hodgkin lymphoma · Ewing sarcoma · germ cell tumor · leiomyosarcoma · lung cancer · rhabdomyosarcoma · teratoma · urinary bladder cancer · breast cancer · childhood germ cell tumor · kidney cancer · small cell lung carcinoma · Burkitt lymphoma · central nervous system neoplasm · extranodal nasal NK/T cell lymphoma · Hodgkins lymphoma · liposarcoma · lymphoblastic lymphoma · peripheral T-cell lymphoma, not otherwise specified · adult acute lymphoblastic leukemia · anaplastic large cell lymphoma · B-cell lymphoma, unclassifiable, with features intermediate between diffuse large b-cell lymphoma and classical Hodgkin lymphoma · cancer of unknown primary site · classic Hodgkin lymphoma · fibrosarcoma · metastatic malignant neoplasm · myxofibrosarcoma · non-small cell lung carcinoma · penile cancer · primary mediastinal large B-cell lymphoma · renal pelvis/ureter urothelial carcinoma · synovial sarcoma · undifferentiated pleomorphic sarcoma · adult fibrosarcoma · ALK-negative anaplastic large cell lymphoma · alveolar soft part sarcoma · angioimmunoblastic T-cell lymphoma · angiosarcoma · B-cell non-Hodgkin lymphoma · cancer · central nervous system germ cell tumor · cervical cancer · chondrosarcoma · choriocarcinoma · enteropathy-associated T-cell lymphoma · Ewing sarcoma of bone · extraosseous osteosarcoma · female breast carcinoma · hepatosplenic T-cell lymphoma · high grade B-cell lymphoma · histiocytoma, Angiomatoid fibrous · localized osteosarcoma · malignant triton tumor · mantle cell lymphoma · mature T-cell and NK-cell non-Hodgkin lymphoma · mixed germ cell tumor · nasal cavity and paranasal sinus neoplasm · nasopharyngeal carcinoma · ovarian carcinoma · penile carcinoma · pleomorphic liposarcoma · pleomorphic rhabdomyosarcoma · pleuropulmonary blastoma · retroperitoneal sarcoma · small intestine cancer · subcutaneous panniculitis-like T-cell lymphoma · supratentorial primitive neuroectodermal tumor · T-cell non-Hodgkin lymphoma · testicular cancer · urethra cancer · uterine corpus sarcoma · yolk sac tumor · acute lymphoblastic leukemia · adult epithelioid sarcoma · adult extraskeletal osteosarcoma · adult intracranial malignant hemangiopericytoma · adult liposarcoma · adult malignant hemangiopericytoma · adult malignant mesenchymoma · aggressive B-cell non-Hodgkin lymphoma · aggressive NK-cell leukemia · alveolar rhabdomyosarcoma · atypical teratoid rhabdoid tumor · B-cell acute lymphoblastic leukemia · B-cell childhood acute lymphoblastic leukemia · brain neoplasm · central nervous system non-hodgkin lymphoma · central nervous system nongerminomatous germ cell tumor · childhood botryoid rhabdomyosarcoma · childhood epithelioid sarcoma · childhood malignant mesenchymoma · childhood testicular germ cell tumor · choriocarcinoma of ovary · choriocarcinoma of testis · clear cell sarcoma · cutaneous undifferentiated pleomorphic sarcoma · dedifferentiated liposarcoma · dermatofibrosarcoma protuberans · desmoplastic small round cell tumor · embryonal carcinoma · epithelioid malignant peripheral nerve sheath tumor · epithelioid sarcoma · extragonadal nonseminomatous germ cell tumor · extragonadal seminoma · extramammary Paget disease · extraskeletal Ewing sarcoma · extraskeletal myxoid chondrosarcoma · fallopian tube cancer · fallopian tube carcinoma · germinoma · head and neck cancer · hepatoblastoma · high grade B-cell lymphoma with MYC and/ or BCL2 and/or BCL6 rearrangement · high-grade B-cell lymphoma double-hit/triple-hit · histiocytic sarcoma · Hodgkin's lymphoma, lymphocytic depletion · Hodgkin's lymphoma, mixed cellularity · infiltrating bladder urothelial carcinoma · inflammatory myofibroblastic tumor · intimal sarcoma · kidney neoplasm · kidney Wilms tumor · large B-cell lymphoma · large-cell immunoblastic lymphoma · low grade fibromyxoid sarcoma · lymphangiosarcoma · lymphoid leukemia · malignant childhood germ cell neoplasm · malignant cutaneous granular cell skin tumor · malignant pancreatic neoplasm · malignant peripheral nerve sheath tumor · malignant testicular germ cell tumor · mediastinal cancer · medulloblastoma · meningioma · mesenchymal chondrosarcoma · mixed phenotype acute leukemia · myelodysplastic syndrome · myeloproliferative neoplasm · myoepithelial tumor · myxoid chondrosarcoma · myxoid liposarcoma · neoplasm of mediastinum · neoplasm of testis · neoplasm with perivascular epithelioid cell differentiation · neuroepithelioma · neurofibrosarcoma · nodular lymphocyte predominant Hodgkin lymphoma · nodular sclerosis classical Hodgkin lymphoma · nongerminomatous germ cell tumor · ovarian carcinosarcoma · ovarian embryonal carcinoma · ovarian yolk sac tumor · pediatric angiosarcoma · pediatric fibrosarcoma · pediatric liposarcoma · pediatric osteosarcoma · pediatric ovarian germ cell tumor · peritoneum cancer · pineal region immature teratoma · pineal region yolk sac tumor · plasma cell neoplasm · precancerous condition · primary brain neoplasm · primary cutaneous diffuse large B-cell lymphoma, Leg type · primary peritoneal carcinoma · primitive neuroectodermal tumor · relapsed/refractory diffuse large B-cell lymphoma · retinoblastoma · skin glomus tumor · soft tissue neoplasm · squamous cell carcinoma · squamous cell carcinoma of penis · T-cell acute lymphoblastic leukemia · T-cell/histiocyte rich large B cell lymphoma · testicular embryonal carcinoma · testicular yolk sac tumor · transitional cell carcinoma · undifferentiated embryonal sarcoma of the liver · undifferentiated high grade pleomorphic sarcoma of bone · urachus cancer · urothelial carcinoma · uterine cancer · uterine carcinosarcoma
Investigated by
National Cancer Institute (NCI) · Children's Oncology Group · Memorial Sloan Kettering Cancer Center · European Organisation for Research and Treatment of Cancer - EORTC · M.D. Anderson Cancer Center · City of Hope Medical Center
+270 more · Samsung Medical Center · UNICANCER · Children's Cancer and Leukaemia Group · Medical Research Council · Eastern Cooperative Oncology Group · Fudan University · Sun Yat-sen University · German Society for Pediatric Oncology and Hematology GPOH gGmbH · Gustave Roussy, Cancer Campus, Grand Paris · St. Jude Children's Research Hospital · Cancer Research UK · Jiangsu HengRui Medicine Co., Ltd. · Mayo Clinic · Qilu Hospital of Shandong University · Radiation Therapy Oncology Group · Spanish Group for Research in Sarcomas · Alliance for Clinical Trials in Oncology · Dana-Farber Cancer Institute · Deutsche Krebshilfe e.V., Bonn (Germany) · French Innovative Leukemia Organisation · Goethe University · H. Lee Moffitt Cancer Center and Research Institute · Institut Claudius Regaud · Peking University People's Hospital · Ruijin Hospital · SWOG Cancer Research Network · Swiss Cancer Institute · University Hospital Muenster · Asan Medical Center · Assistance Publique - Hôpitaux de Paris · Brigham and Women's Hospital · Charite University, Berlin, Germany · Children's Cancer Group, China · Columbia University · Dutch Childhood Oncology Group · EBMT Solid Tumors Working Party · ECOG-ACRIN Cancer Research Group · European Lung Cancer Working Party · European Paediatric Soft Tissue Sarcoma Study Group · First Hospital of China Medical University · Fondazione IRCCS Istituto Nazionale dei Tumori, Milano · Genentech, Inc. · Gynecologic Oncology Group · Hannover Medical School · Herbert Irving Comprehensive Cancer Center · Hoffmann-La Roche · Institut Bergonié · Italian Association for Pediatric Hematology Oncology · Italian Sarcoma Group · Masonic Cancer Center, University of Minnesota · Merck Sharp & Dohme LLC · Nanjing Children's Hospital · National Institutes of Health (NIH) · New York Medical College · Northwestern University · Oslo University Hospital · Regione Lombardia · Scandinavian Sarcoma Group · Second Affiliated Hospital, School of Medicine, Zhejiang University · Shandong Cancer Hospital and Institute · Shanghai Children's Medical Center · Shanghai Zhongshan Hospital · Shanxi Province Cancer Hospital · Societe Francaise Oncologie Pediatrique · The First Affiliated Hospital with Nanjing Medical University · The Second Affiliated Hospital of Dalian Medical University · Tianjin Medical University Cancer Institute and Hospital · Tongji Hospital · University of Alabama at Birmingham · University of Chicago · University of Miami · West China Second University Hospital · Zhejiang Cancer Hospital · 307 Hospital of PLA · all 276 on the full record

Regulatory milestones approvals, filings & regulatory actions · 1 recorded

MilestoneJurisdictionBrandIndicationDateSentence it was read from
Approved US (FDA) IFEX/MESNEX KIT — 1987-08-14 fda.gov ↗

Trials 295 · started per year

today
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PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 04 trials
Phase 0 NCT06204614 Jun 2024 → Jul 2028 expected infiltrating bladder urothelial carcinoma Brigham and Women's Hospital Enrolling by invitation No outcome recorded
Phase 0 NCT04947501 Jun 2021 → Jun 2026 overdue childhood malignant neoplasm, neuroblastoma Memorial Sloan Kettering Cancer Center Active not recruiting No outcome recorded
Phase 0 NCT03719105 Mar 2019 → Dec 2027 expected aggressive NK-cell leukemia New York Medical College Recruiting No outcome recorded
Phase 0 NCT00662233 Oct 1991 → Oct 2013 ovarian cancer, sarcoma Mayo Clinic Completed No outcome recorded
Phase 112 trials
Phase 1 NCT07194044 Feb 2026 → Oct 2030 expected Ewing sarcoma H. Lee Moffitt Cancer Center and Research Institute Recruiting No outcome recorded
Phase 1 NCT05813327 Mar 2024 → Apr 2026 soft tissue sarcoma Washington University School of Medicine Terminated No outcome recorded Stop: Enrollment
Phase 1 NCT06164327 Dec 2023 → Oct 2025 relapsed/refractory diffuse large B-cell lymphoma BeBetter Med Inc Unknown No outcome recorded
Phase 1 NCT03440567 Jun 2018 → Jun 2024 diffuse large B-cell lymphoma, mantle cell lymphoma City of Hope Medical Center Completed No outcome recorded
Phase 1 NCT03034304 Feb 2017 → Nov 2023 cancer HRYZ Biotech Co. Terminated No outcome recorded Stop: Business
Phase 1 NCT02677116 Aug 2016 → Oct 2018 metastatic neoplasm Eli Lilly and Company Completed No outcome recorded
Phase 1 NCT01258634 Jul 2010 → Nov 2011 osteosarcoma, respiratory system cancer University of Chicago Terminated No outcome recorded Stop: Enrollment
Phase 1 NCT00086970 Jun 2004 → Nov 2005 cancer of unknown primary site National Cancer Institute (NCI) Terminated No outcome recorded
Phase 1 NCT00030784 Nov 2001 → Mar 2005 sarcoma European Organisation for Research and Treatment of Cancer - EORTC Completed No outcome recorded
Phase 1 NCT00003198 Nov 1997 → May 2000 cancer of unknown primary site Memorial Sloan Kettering Cancer Center Completed No outcome recorded
Phase 1/223 trials · 1 missed
Phase 1/2 NCT06239272 Mar 2024 → Jun 2034 expected angiosarcoma, extraosseous osteosarcoma, fibrosarcoma, histiocytoma, Angiomatoid fibrous +3 St. Jude Children's Research Hospital Recruiting No outcome recorded
Phase 1/2 NCT05590572 Jan 2023 → Dec 2026 expected osteosarcoma Second Affiliated Hospital, School of Medicine, Zhejiang University Not yet recruiting No outcome recorded
Phase 1/2 NCT05533775 Nov 2022 → Nov 2029 expected B-cell non-Hodgkin lymphoma Hoffmann-La Roche Recruiting No outcome recorded
Phase 1/2 NCT04981899 Mar 2021 → May 2026 overdue Hodgkins lymphoma St. Petersburg State Pavlov Medical University Active not recruiting No outcome recorded
Phase 1/2 NCT04625907 Sep 2020 → Jun 2030 expected rhabdomyosarcoma University of Birmingham Recruiting No outcome recorded
Phase 1/2 NCT04044378 Aug 2019 → Sep 2021 pediatric osteosarcoma Peking University People's Hospital Withdrawn No outcome recorded
Phase 1/2 NCT03277924 May 2017 → Jun 2024 bone sarcoma, soft tissue sarcoma Spanish Group for Research in Sarcomas Completed No outcome recorded
Phase 1/2 NCT02432274 Dec 2014 → Jul 2019 differentiated thyroid carcinoma, osteosarcoma Eisai Inc. Completed Missed primary
Phase 1/2 NCT02227199 Oct 2014 → Mar 2020 Hodgkins lymphoma University of Washington Completed No outcome recorded
Phase 1/2 NCT01966913 Apr 2012 → Mar 2019 germ cell tumor Assistance Publique - Hôpitaux de Paris Unknown No outcome recorded
Phase 2158 trials · 1 missed
Phase 2 NCT06835049 Oct 2025 → Mar 2028 expected soft tissue sarcoma Swiss Cancer Institute Recruiting No outcome recorded
Phase 2 NCT06849986 Feb 2025 → Dec 2027 expected angiosarcoma, desmoplastic small round cell tumor, fibrosarcoma, leiomyosarcoma +2 Fudan University Recruiting No outcome recorded
Phase 2 NCT06816771 Feb → Dec 2025 overdue rhabdomyosarcoma Shandong Cancer Hospital and Institute Recruiting No outcome recorded
Phase 2 NCT06684327 Nov 2024 → Dec 2026 expected extramammary Paget disease, penile cancer, rhabdomyosarcoma, testicular cancer +1 Fudan University Recruiting No outcome recorded
Phase 2 NCT07243626 Sep 2024 → Dec 2026 expected soft tissue sarcoma Second Affiliated Hospital, School of Medicine, Zhejiang University Recruiting No outcome recorded
Phase 2 NCT06528496 Jul 2024 → Jul 2029 expected neuroblastoma Memorial Sloan Kettering Cancer Center Recruiting No outcome recorded
Phase 2 NCT06415318 May 2024 → Jun 2027 expected penile carcinoma Sun Yat-sen University Recruiting No outcome recorded
Phase 2 NCT06593899 May 2024 → Dec 2025 soft tissue sarcoma Fujian Medical University Union Hospital Unknown No outcome recorded
Phase 2 NCT05827549 Apr 2024 → Dec 2032 expected acute lymphoblastic leukemia Ho Joon Im Recruiting No outcome recorded
Phase 2 NCT04838652 Mar 2024 → May 2026 overdue classic Hodgkin lymphoma University of Cologne Recruiting No outcome recorded
Show all 158 trials opens the full record — a long page
Phase 2/33 trials · 1 met primary
Phase 2/3 NCT06341998 Jun 2020 → Jan 2024 yolk sac tumor Shandong First Medical University Completed No outcome recorded
Phase 2/3 NCT02180867 Aug 2014 → Jun 2019 alveolar soft part sarcoma, clear cell sarcoma, cutaneous undifferentiated pleomorphic sarcoma, epithelioid malignant peripheral nerve sheath tumor +19 National Cancer Institute (NCI) Completed Met primary
Phase 2/3 NCT00045461 Jun 2000 → ? fallopian tube cancer, ovarian cancer, peritoneum cancer Ludwig-Maximilians - University of Munich Unknown No outcome recorded
Phase 366 trials · 4 met primary · 11 missed
Phase 3 NCT07823491 Dec 2026 → Dec 2028 expected liposarcoma, undifferentiated pleomorphic sarcoma Ohio State University Comprehensive Cancer Center Not yet recruiting No outcome recorded
Phase 3 NCT06647953 Mar 2025 → Mar 2029 expected pleuropulmonary blastoma Children's Oncology Group Recruiting No outcome recorded
Phase 3 NCT06520163 Aug 2024 → Aug 2026 overdue non-Hodgkin lymphoma The Affiliated People's Hospital of Ningbo University Recruiting No outcome recorded
Phase 3 NCT05711628 Aug 2023 → Jun 2028 classic Hodgkin lymphoma National Cancer Institute (NCI) Withdrawn No outcome recorded
Phase 3 NCT04833114 Apr 2021 → Dec 2025 diffuse large B-cell lymphoma GWT-TUD GmbH Completed No outcome recorded
Phase 3 NCT04881838 Mar 2021 → Mar 2026 overdue anaplastic large cell lymphoma Children's Cancer Group, China Active not recruiting No outcome recorded
Phase 3 NCT04031677 Jan 2021 → Apr 2027 expected leiomyosarcoma, liposarcoma, retroperitoneal sarcoma European Organisation for Research and Treatment of Cancer - EORTC Recruiting No outcome recorded
Phase 3 NCT04486391 Dec 2020 → Oct 2025 classic Hodgkin lymphoma BeiGene Terminated No outcome recorded Stop: Business
Phase 3 NCT04307277 Oct 2020 → Oct 2032 expected soft tissue sarcoma Institut Claudius Regaud Recruiting No outcome recorded
Phase 3 NCT04221035 Nov 2019 → Nov 2026 expected neuroblastoma Gustave Roussy, Cancer Campus, Grand Paris Recruiting No outcome recorded
Phase 410 trials · 1 met primary
Phase 4 NCT05844813 Nov 2022 → Nov 2025 overdue retroperitoneal sarcoma Peking University International Hospital Enrolling by invitation No outcome recorded
Phase 4 NCT03514381 May 2018 → Nov 2020 soft tissue sarcoma Institut Claudius Regaud Completed No outcome recorded
Phase 4 NCT03071822 Feb 2017 → Jul 2021 T-cell non-Hodgkin lymphoma The University of Hong Kong Unknown No outcome recorded
Phase 4 NCT01746992 Sep 2012 → Sep 2018 ALK-negative anaplastic large cell lymphoma, angioimmunoblastic T-cell lymphoma, enteropathy-associated T-cell lymphoma, hepatosplenic T-cell lymphoma +2 Ruijin Hospital Unknown No outcome recorded
Phase 4 NCT01424839 Oct 2011 → Oct 2018 central nervous system germ cell tumor University Hospital Muenster Unknown No outcome recorded
Phase 4 NCT01501149 Jan 2011 → Dec 2015 extranodal nasal NK/T cell lymphoma Mingzhi Zhang Unknown Met primary
Phase 4 NCT00199082 Jul 2002 → Jun 2010 Burkitt lymphoma, anaplastic large cell lymphoma, lymphoblastic lymphoma, neoplasm of mediastinum Nicola Goekbuget Completed No outcome recorded
Phase 4 NCT00199056 Oct 1999 → Nov 2003 adult acute lymphoblastic leukemia Goethe University Completed No outcome recorded
Phase 4 NCT00199095 Feb 1997 → Jun 2003 adult acute lymphoblastic leukemia Goethe University Completed No outcome recorded
Phase 4 NCT00199069 Apr 1993 → Jan 1999 adult acute lymphoblastic leukemia Goethe University Completed No outcome recorded
Phase not applicable18 trials
— NCT07389356 Feb 2026 → Oct 2027 expected diffuse large B-cell lymphoma The First Affiliated Hospital with Nanjing Medical University Not yet recruiting No outcome recorded
— NCT04199026 Feb 2025 → Dec 2028 expected sarcoma M.D. Anderson Cancer Center Recruiting No outcome recorded
— NCT06451302 Apr 2024 → May 2027 expected Ewing sarcoma Yizhuo Zhang Active not recruiting No outcome recorded
— NCT05705687 May 2023 → Feb 2031 expected nongerminomatous germ cell tumor Gustave Roussy, Cancer Campus, Grand Paris Recruiting No outcome recorded
— NCT05784987 Apr 2023 → Jan 2024 diffuse large B-cell lymphoma The First Affiliated Hospital with Nanjing Medical University Unknown No outcome recorded
— NCT01795430 Jul 2013 → Mar 2018 Ewing sarcoma of bone, extraskeletal Ewing sarcoma, supratentorial primitive neuroectodermal tumor City of Hope Medical Center Withdrawn No outcome recorded Stop: Enrollment
— NCT01490060 May 2012 → Mar 2016 chemotherapy-induced toxicity, sarcoma M.D. Anderson Cancer Center Completed No outcome recorded
— NCT01505569 Oct 2011 → Feb 2024 Ewing sarcoma, atypical teratoid rhabdoid tumor, germ cell tumor, hepatoblastoma +6 Masonic Cancer Center, University of Minnesota Completed No outcome recorded
— NCT01156883 Apr 2010 → Oct 2017 leukemia GIMEMA Foundation Completed No outcome recorded
— NCT01464606 Dec 2009 → Dec 2025 overdue pleuropulmonary blastoma Children's Hospitals and Clinics of Minnesota Active not recruiting No outcome recorded
Phase not stated1 trial · 1 met primary
— NCT00517894 — lymphoma Study Group of Medical Tumour Therapy (AGMT) No longer available Met primary
Comparator or background therapy165 trials
Phase 0 NCT01331590 Background Jul 2011 → Oct 2014 precursor lymphoblastic lymphoma/leukemia Washington University School of Medicine Completed No outcome recorded
Phase 0 NCT00515138 Background May 2007 → Nov 2011 B-cell non-Hodgkin lymphoma University of California, San Francisco Terminated No outcome recorded Stop: Enrollment
Phase 1 NCT06156410 Background Oct 2023 → Nov 2027 expected Ewing sarcoma, osteosarcoma Children's Hospital of Philadelphia Recruiting No outcome recorded
Phase 1 NCT05364424 Background Nov 2022 → Oct 2025 diffuse large B-cell lymphoma Hoffmann-La Roche Completed No outcome recorded
Phase 1 NCT04151810 Background Dec 2019 → Oct 2022 — Dragonboat Biopharmaceutical Company Limited Completed No outcome recorded
Show all 165 trials opens the full record — a long page

News releases announcing trial results or a regulatory action · 2

DateIssuerRelease
2024-11-05 Hoffmann-La Roche Results Roche to present new and encouraging long-term follow-up data across broad haematology portfolio at ASH 2024 roche.com ↗
Glofitamab in Combination with Rituximab plus Ifosfamide, Carboplatin, and Etoposide shows Favorable Efficacy and Manageable Safety in Patients with Relapsed or Refractory Diffuse Large B-cell Lymphoma
2024-11-05 Genentech, Inc. Results Genentech to Present New and Encouraging Long-term Follow-up Data Across Broad Hematology Portfolio at ASH 2024 gene.com ↗
Glofitamab in Combination with Rituximab plus Ifosfamide, Carboplatin, and Etoposide shows Favorable Efficacy and Manageable Safety in Patients with Relapsed or Refractory Diffuse Large B-cell Lymphoma

Evidence & citations 16 cited values

Every value below carries the sentence it was read from. 461 sources stand behind the page.

FieldValueCited text
Known as ifosfamide “including but not limited to DHAP (dexamethasone, cisplatin, high-dose cytarabine), ESHAP (etoposide, methylprednisolone, high-dose cytarabine and cisplatin), DICE...” NCT04486391 ↗
456

“Drugs:Chidamide and ICE regimen (ifosfamide, Mesna,Carboplatin and etoposide): Chidamide 20mg on d1,4,8,11;ifosfamide 1.2g/ m2,d1-4,ivg during 4 hours; Mesna 0.4g, 0,4,8 hours...” NCT02856997 ↗

“treatment consisted of six to eight rituximab infusions and four to six courses of intensive chemotherapy (attenuated in patients aged >55 years) with high-dose methotrexate,...” PMID 23753030 ↗ Jun 2013

“Immunochemotherapy in Primary Central Nervous System Lymphoma With Rituximab, HD-MTX, HD-Ara C, Cyclophosphamide, Ifosfamide, Vincristine, Vindesine, Temozolomide and DepoCyte...” NCT01458730 ↗

“Patients with a persistently positive interim-PET scan assigned to arm B2 will receive six blocks of the B-ALL protocol (rituximab, methotrexate, ifosfamide, etoposide,...” NCT00554164 ↗

“The histological type of squamous cells carcinoma, which is the large majority of penile cancer, led Pagliaro et al. [10] to explore a combination of Paclitaxel, Ifosfamide and...” NCT02014831 ↗

“Chemotherapy agents may include doxorubicin, ifosfamide, docetaxel, CHOP regimen, etoposide, cyclophosphamide and vincristine which will be administered as per standard of care...” NCT04570423 ↗

“Radiotherapy Technique: IMRT Total dose: 50 Gy Per fraction: 2 Gy Chemotherapy: q3w Dexamethasone 40 mg d1-4 Ifosfamide 1200mg/m2 d1-4 Etoposide 60 mg/m2 d1-4 Cisplatin 20mg/m2...” NCT01667302 ↗

“Three courses of doxorubicin and ifosfamide (AI, doxorubicin 75 mg/sqm and ifosfamide 10 g/sqm with prophylactic mesna), one before radiotherapy and two within the gap between...” NCT03651375 ↗

“Induction treatment with: 4 cycle of Vincristine (9mg/,2), Dactinomycin (6mg/m2), Doxorubicin (160mg/m2), Cyclophosphamide (2.4g/m2), Ifosfamide (18g/M2) and Etoposide...” NCT02063022 ↗

“This trial is to evaluate the efficacy of concurrent chemoradiotherapy with cisplatin followed by VIPD (etoposide, ifosfamide, cisplatin, dexamethasone) in localized NK/T-cell...” NCT00418535 ↗

Show 446 more sources

Known as Ifex ChEMBL registry synonym — accepted as the source's own label CHEMBL1024 ↗
Known as IFF “The IVAC chemotherapy regimen comprises ifosfamide (IFF) IV over 1 hour and etoposide IV over 1 hour on days 1-5 and ARA-C IV over 3 hours on days 1 and 2.” NCT00040690 ↗
3

“ifosfamide (IFF) IV over 1 hour on days 1-5” NCT00006455 ↗

“Ifosfamide, IFF, NSC-109724;” NCT00001300 ↗

“IFF Ifosfamide, NSC-109724” NCT00002565 ↗

Known as IFO “AI: Doxorubicin (ADM) 60mg/m2 iv D1+ Ifosfamide (IFO) 2g/m2/d D1-5+ Mesna 400mg/m 2 (ifosfamide start infusion, time after infusion 4 hours, 8 hours injection) D1-5, Q3W” NCT04699214 ↗
5

“pegylated liposomal doxorubicin (PLD) combined with ifosfamide (IFO) as the first-line treatment for patients with advanced or metastatic soft-tissue sarcoma (STS).” PMID 36239473 ↗ Dec 2022

“Envafolimab combined with an AI regimen: liposomal doxorubicin 35 mg/m² on day 1; IFO 2.5 mg/m² on days 1-3, intravenous infusion, every 3 weeks.” NCT07243626 ↗

“Etoposide + Ifosfamide (IFO) + Carboplatin] ± Rituximab” NCT06520163 ↗

“Ifosfamide (IFO) 3 g/m2/day on days 1 to 3” NCT06849986 ↗

“Pirarubicin (THP) + Ifosfamide (IFO)” NCT03121833 ↗

Known as Ifosfamida ChEMBL registry synonym — accepted as the source's own label CHEMBL1024 ↗
Known as Ifosfamide - Ifex “Ifosfamide - Ifex” NCT00093509 ↗
Known as Ifsofamide ChEMBL registry synonym — accepted as the source's own label CHEMBL1024 ↗
Known as isocyclophosphamide “Participant will receive albumin-paclitaxel 260mg/m2 d1, isocyclophosphamide 1500mg/m2 d2-5, and cisplatin 25mg/m2 d2-5 every 21 days until disease progression, intolerable...” NCT06684327 ↗
Known as Isophosphamide ClinicalTrials.gov intervention name — accepted as the source's own label NCT05590572 ↗
1

NCT05784987 ↗

Known as Mitoxana ChEMBL registry synonym — accepted as the source's own label CHEMBL1024 ↗
Known as MJF 9325 ChEMBL registry synonym — accepted as the source's own label CHEMBL1024 ↗
Known as NSC-109724 “Ifosfamide, IFF, NSC-109724;” NCT00001300 ↗
1

“IFF Ifosfamide, NSC-109724” NCT00002565 ↗

Known as Z-4942 ChEMBL registry synonym — accepted as the source's own label CHEMBL1024 ↗
Action Inhibit “Ifosfamide is designed to stop the growth of cancer cells, which may cause the cells to die.” NCT00673179 ↗
Modality Small molecule “structural analogue of cyclophosphamide” NCT06528496 ↗
Route Intravenous “Regimen B: Patients receive etoposide IV over 1 hour, followed immediately by ifosfamide IV over 1 hour on days 1-5.” NCT00002466 ↗