drugset / Trial / NCT00002764
Surgery With or Without Combination Chemotherapy in Treating Patients With Lung Metastases From Soft Tissue Sarcoma
Phase 3
Completed
340 enrolled
European Organisation for Research and Treatment of Cancer - EORTC
Eastern Cooperative Oncology Group · collabSWOG Cancer Research Network · collabScandinavian Sarcoma Group · collab
RandomizedTreatment
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. It is not yet known whether surgery plus combination chemotherapy is more effective than surgery alone in treating patients with lung metastases from soft tissue sarcoma. PURPOSE: Randomized phase III trial to compare the effectiveness of surgery plus combination chemotherapy with that of surgery alone in treating patients who have soft tissue sarcoma that has spread to the lung.
Timeline
- Start
- 1996-04
- Primary completion
- 2000-11
- Completion
- —
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Doxorubicin | Other / unclassified | — | Intravenous |
| Subject | Ifosfamide | Small molecule | — | Intravenous |
| Subject | filgrastim | Protein / enzyme biologic | — | Subcutaneous |