drugset / Trial / NCT04486391

Tislelizumab Monotherapy Versus Salvage Chemotherapy for Relapsed/Refractory Classical Hodgkin Lymphoma

NCT04486391

Phase 3 Terminated 3 enrolled BeiGene
RandomizedParallel-groupOpen-labelTreatment

Summary

The primary objective of this study is to evaluate the efficacy of tislelizumab in participants with relapsed or refractory classical Hodgkin lymphoma (cHL), as measured by Progression-free Survival (PFS) as assessed by investigator

Timeline

Start
2020-12-14
Primary completion
2025-10-13
Completion
2025-10-13

Drugs

EvaluationDrugModalityDoseRoute
Subject 2-MERCAPTOETHANESULFONIC ACID Small molecule
Subject Carboplatin Small molecule
Subject Cisplatin Other / unclassified
Subject Cytarabine Small molecule
Subject Dexamethasone Small molecule
Subject Doxorubicin Other / unclassified
Subject Etoposide Small molecule
Subject Gemcitabine Small molecule
Subject Ifosfamide Small molecule
Subject Methylprednisolone Other / unclassified
Subject Mitoxantrone Small molecule
Subject Prednisone Other / unclassified
Subject Tislelizumab Monoclonal antibody 200 mg Intravenous
Subject Vinorelbine Small molecule