Takeda Receives Positive CHMP Opinion for ADCETRIS ® (brentuximab vedotin) in Combination with CHP (Cyclophosphamide, Doxorubicin and Prednisone) for Treatment of Adult Patients with Previously Untreated Systemic Anaplastic Large Cell Lymphoma takeda.com ↗
2006-04-12
Teva Branded Pharmaceutical Products R&D, Inc.
Teva Announces Approval of Mitoxantrone Hydrochloride Injection USP tevapharm.com ↗
Evidence & citations 26 cited values
Every value below carries the sentence it was read from.
372 sources stand behind the page.
Field
Value
Cited text
Known as
mitoxantrone
“including but not limited to DHAP (dexamethasone, cisplatin, high-dose cytarabine), ESHAP (etoposide, methylprednisolone, high-dose cytarabine and cisplatin), DICE...” NCT04486391 ↗336
“Therapy of AML in Patients Older Than 60 Years: Randomized Comparison of a Double Induction With Daunorubicin and AraC (as Continuous Infusion) With a Double Induction With...” NCT00180167 ↗
“Investigator's choice treatment with chidamide, golidocitinib, mitoxantrone hydrochloride liposome, or gemcitabine hydrochloride administered according to the respective...” NCT07639879 ↗
“An Open-label, Multi-center, Phase 2 Study of Liposome-entrapped Mitoxantrone Hydrochloride Injection (PLM60) in Subjects With Relapsed Small-cell Lung Cancer After...” NCT04352413 ↗
“Liposomal mitoxantrone hydrochloride injection (Doxorubicin®): Used after dilution with 250mL of 5% glucose injection (50mg/mL), with an intravenous drip time of at least 60 minutes.” NCT06651866 ↗
“High intensity: intermediate or high dose cytarabine (HiDAC); mitoxantrone, etoposide, and cytarabine (MEC); or fludarabine, cytarabine, G-CSF, +/- idarubicin (FLAG/FLAG-Ida).” NCT02920008 ↗
“* EA±Mitox regimen: etoposide injection 100 mg/m2, cytarabine injection 100-150 mg/m2, mitoxantrone injection 8 mg/m2 QD IV for 5 consecutive days (Days 1-5).” NCT06387069 ↗
“Mitoxantrone hydrochloride liposome, carmostine, etoposide and cytarabine will be used as conditioning regimen for ASCT in the lymphoma patients.” NCT05681403 ↗
“high dose ARA-C consolidation together with high cumulative dose of anthracyclines daunorubicin, idarubicin, mitoxantrone(720-660 mg/m2)” NCT01587430 ↗
“Participants on mitoxantrone, etoposide, cytarabine(MEC) will receive 8 mg/m\^2 of mitoxantrone daily by IV for 3 days (day 1 to 3)” NCT05876832 ↗
“haM Cytarabine 1 g/m2 every 12 hours for 3 days; Mitoxantrone 10 mg/m2 days 4 and 5, intrathecal cytarabine days 6 and 15.” NCT06211452 ↗
“chemotherapy consisting of Cladribine (5mg/m2), cytarabine (1.5g/m2) and mitoxantrone （10mg/m2）for 5 days” NCT02910752 ↗
“oral bcl-2 inhibitor plus IM2(Ifosfamide plus Mitoxantrone or Idarubicin plus methotrexate) chemotherapy” NCT05576532 ↗
“The ALLR3 chemotherapy regimen (vincristine, mitoxantrone, dexamethasone, and PEG-asparaginase” NCT05748171 ↗
“Rituximab: 375 mg/mq day 1, Fludarabina: 25 mg/mq day 1-3, Mitoxantrone: 10 mg/mq day 1,” NCT00774826 ↗
“Mitoxantrone Hydrochloride Liposome Injection is a kind of anthraquinone compounds” NCT02595242 ↗
“NOVE-HiDAC consists of mitoxantrone, etoposide, and modified high-dose cytarabine.” NCT01222143 ↗
“Mitoxantrone hydrochloride liposome will be given on day 1 at dose of 18 mg/m2” NCT06244368 ↗
“Early induction intensification with cladribine, cytarabine, and mitoxantrone” PMID 31661339 ↗Oct 2019
“Liposomal mitoxantrone hydrochloride injection (Doxorubicin®): Used after dilution with 250mL of 5% glucose injection (50mg/mL), with an intravenous drip time of at least 60 minutes.” NCT06651866 ↗
Known as
Lipo-MIT
“PURPOSE: This trial aimed to evaluate the efficacy and safety of mitoxantrone hydrochloride liposome injection (Lipo-MIT) in advanced breast cancer (ABC).” PMID 34633576 ↗Oct 20213
“mitoxantrone hydrochloride liposome (Lipo-MIT) plus cyclophosphamide, vincristine, etoposide, and prednisone (COEP) in untreated PTCL.” PMID 40292284 ↗Apr 2025
“Mitoxantrone hydrochloride liposome (Lipo-MIT) has shown clinical benefits in various tumors.” PMID 40232151 ↗Apr 2025
“CSPC Pharmaceutical Group has developed the liposomal formulation of mitoxantrone” NCT06220097 ↗
Known as
liposomal mitoxantrone
“In the pivotal phase II study of liposomal mitoxantrone” NCT06220097 ↗
Known as
Liposomal mitoxantrone hydrochloride
“Drug: Liposomal mitoxantrone hydrochloride (12mg/m2, 16mg/m2, 20mg/m2, 24mg/m2) is administered by an intravenous infusion (IV) on day 1 of each 21-day cycle.” NCT04509466 ↗
Known as
MITO
“Mitoxantrone (MITO, Novantrone®), a synthetic anthracenedione approved for worsening relapsing-remitting multiple sclerosis (MS) and secondary progressive MS, has been shown to...” NCT00304291 ↗
“Liposome entrapped mitoxantrone (LEM) is a mixture of commercially available mitoxantrone HCL (Novantrone) and a combination of lyophilized lipids.” NCT00024492 ↗
Known as
Mitoxantrone hydrochloride
“Mitoxantrone hydrochloride, a synthetic anthracenedione approved for worsening relapsing-remitting multiple sclerosis and secondary progressive multiple sclerosis, has been...” PMID 16831964 ↗Jul 200651
“An Open-label, Multi-center, Phase 2 Study of Liposome-entrapped Mitoxantrone Hydrochloride Injection (PLM60) in Subjects With Relapsed Small-cell Lung Cancer After...” NCT04352413 ↗
“A Single-arm, Open-label, Single-center Phase Ib Study to Evaluate the Safety and Efficacy of Liposome-entrapped Mitoxantrone Hydrochloride Injection (PLM60) in Advanced...” NCT04331743 ↗
“M: mitoxantrone (mitoxantrone hydrochloride), 40 mg/m2 by IV infusion over 1-2 hours starting 12 hours after completing cytarabine” NCT02520011 ↗
“To study the toxicity and efficacy of IV mitoxantrone hydrochloride (Novantrone) in AIDS-related Kaposi's sarcoma.” NCT00002259 ↗
“Mitoxantrone Hydrochloride was given at a dose of 12mg/m\^2/day I.V. on days 1, 2, and 3.” NCT00268242 ↗
“Patients receive mitoxantrone hydrochloride IV over 5 minutes once a week for 3 weeks.” NCT00627354 ↗
“Mitoxantrone hydrochloride liposome intravenous infusion on day 1 (30mg/m2)” NCT05941585 ↗
“This is a multicenter, randomized, open-label, phase Ib study to evaluate the safety, efficacy and pharmacokinetic characteristics of Mitoxantrone Hydrochloride Liposome in...” NCT04719065 ↗6
“This is a multicenter, open-label, single-arm, phase Ib study to evaluate the safety and efficacy of Mitoxantrone Hydrochloride Liposome in subjects with recurrent/metastatic...” NCT04902027 ↗
“mitoxantrone hydrochloride liposome (Lipo-MIT) plus cyclophosphamide, vincristine, etoposide, and prednisone (COEP) in untreated PTCL.” PMID 40292284 ↗Apr 2025
“Mitoxantrone Hydrochloride Liposome is a liposomal formulation of the anthracenedione chemotherapy agent mitoxantrone.” NCT07372352 ↗
“Drug: Mitoxantrone hydrochloride liposome Mitoxantrone hydrochloride liposome (18 mg/m\^2) on day 1, every 3 weeks” NCT06433362 ↗
“All subjects will receive Mitoxantrone Hydrochloride Liposome 20 mg/m2, IV, on day 1 of each 21-day cycle (q3w).” NCT04718376 ↗
“Mitoxantrone hydrochloride liposome 24 mg/m2, IV every 4 weeks, day 1” NCT06345365 ↗
Known as
Mitoxantrone Hydrochloride Liposome Injection
“PURPOSE: This trial aimed to evaluate the efficacy and safety of mitoxantrone hydrochloride liposome injection (Lipo-MIT) in advanced breast cancer (ABC).” PMID 34633576 ↗Oct 20212
“A Study of Mitoxantrone Hydrochloride Liposome Injection in the Treatment of Recurrent/Metastatic Head and Neck Cancers” NCT04902027 ↗
“M: Mitoxantrone Hydrochloride Liposome Injection: 15 mg/m², IV, on Day 1, every 4 weeks (q4w)” NCT06741722 ↗
Known as
mitoxantrone liposome hydrochloride
“The recommended dose of mitoxantrone liposome hydrochloride is not limited.” NCT06220097 ↗
Known as
Mitozantrone
ClinicalTrials.gov intervention name — accepted as the source's own labelNCT00100477 ↗1
“Mitoxantrone (MTX): 3g/m2, i.v., in 24 hours, day 1, 28 and 56.” NCT00526305 ↗
Known as
Novantrone
“Mitoxantrone (MITO, Novantrone®), a synthetic anthracenedione approved for worsening relapsing-remitting multiple sclerosis (MS) and secondary progressive MS, has been shown to...” NCT00304291 ↗5
“Liposome entrapped mitoxantrone (LEM) is a mixture of commercially available mitoxantrone HCL (Novantrone) and a combination of lyophilized lipids.” NCT00024492 ↗
“To study the toxicity and efficacy of IV mitoxantrone hydrochloride (Novantrone) in AIDS-related Kaposi's sarcoma.” NCT00002259 ↗
“An Open-label, Multi-center, Phase 2 Study of Liposome-entrapped Mitoxantrone Hydrochloride Injection (PLM60) in Subjects With Relapsed Small-cell Lung Cancer After...” NCT04352413 ↗1
“Plm60-s is a pegylated liposomal mitoxantrone formulation, in which mitoxantrone was loaded into small unilamellar vesicles (~60 nm) made from solid lipid membrane.” PMID 25034977 ↗Jul 2014