drugset / Trial / NCT00006250

Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage III or Stage IV Non-Hodgkin's Lymphoma

NCT00006250

Phase 3 Unknown 500 enrolled Lymphoma Trials Office
RandomizedTreatment

Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. It is not yet known which combination chemotherapy regimen is more effective for non-Hodgkin's lymphoma. PURPOSE: Randomized phase III trial to compare the effectiveness of two different combination chemotherapy regimens in treating patients who have stage III or stage IV non-Hodgkin's lymphoma.

Timeline

Start
2000-05
Primary completion
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject Chlorambucil Other / unclassified Oral
Subject Dexamethasone Small molecule Oral
Subject Fludarabine Small molecule Intravenous
Subject Mitoxantrone Small molecule Intravenous

Indications