drugset / Trial / NCT00017563
Combination Chemotherapy Followed by Surgery in Treating Patients With Localized Prostate Cancer
NaSingle-groupOpen-labelTreatment
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug and giving chemotherapy before surgery may shrink the tumor so that it can be removed during surgery. PURPOSE: Phase I/II trial to study the effectiveness of combination chemotherapy followed by surgery in treating patients who have localized prostate cancer.
Timeline
- Start
- 2000-09
- Primary completion
- 2010-05
- Completion
- —
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Mitoxantrone | Small molecule | 2 mg/m2 | — |
| Subject | Mitoxantrone | Small molecule | 6 mg/m2 | — |
| Background | Docetaxel | Small molecule | 35 mg/m2 | Intravenous |