drugset / Trial / NCT06760039
Safety and Efficacy of R-CMOP Versus R-CHOP in the Initial Treatment of DLBCL
RandomizedParallel-groupOpen-labelTreatment
Summary
This is a prospective, randomized, controlled, multicenter, phase II clinical trial to evaluate the efficacy and safety of R-CMOP versus R-CHOP in the initial treatment of low-risk and medium-risk diffuse large B-cell lymphoma (DLBCL).
Timeline
- Start
- 2025-01-10
- Primary completion
- 2028-08-31
- Completion
- 2028-11-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Doxorubicinin | Unknown | — | Intravenous |
| Subject | Mitoxantrone | Small molecule | — | Intravenous |
| Background | Cyclophosphamide | Other / unclassified | — | Intravenous |
| Background | Prednisone | Other / unclassified | — | Oral |
| Background | Rituximab | Monoclonal antibody | — | Intravenous |
| Background | Vincristine | Small molecule | — | Intravenous |