drugset / Trial / NCT05344742
A Study of Mitoxantrone Hydrochloride Liposome Injection Combination Therapy in Chinese Patients With Advanced Solid Tumors
Non-randomizedParallel-groupOpen-labelTreatment
Summary
The purpose of this study is to evaluate the tolerability, safety, pharmacokinetics (PK) and efficacy of mitoxantrone hydrochloride liposome injection combination therapy in Chinese patients with advanced solid tumors.
Timeline
- Start
- 2022-04
- Primary completion
- 2024-03
- Completion
- 2025-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Capecitabine | Small molecule | 1000 mg/m2 | Oral |
| Subject | Mitoxantrone | Small molecule | 18 mg/m2 | Intravenous |
| Subject | Mitoxantrone | Small molecule | 24 mg/m2 | Intravenous |
| Subject | Mitoxantrone | Small molecule | 30 mg/m2 | Intravenous |
| Subject | Paclitaxel | Small molecule | 260 mg/m2 | — |