drugset / Trial / NCT00003407
Amifostine & High-Dose Combination Chemotherapy in Treating Patients With Acute ML or CML
NaSingle-groupOpen-labelSupportive care
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Chemoprotective drugs, such as amifostine, may protect normal cells from the side effects of chemotherapy. PURPOSE: Phase II trial to study the effectiveness of amifostine and high-dose combination chemotherapy in treating patients with acute myeloid leukemia or chronic myelogenous leukemia.
Timeline
- Start
- 2001-02-13
- Primary completion
- 2004-04-07
- Completion
- 2004-04-07
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cytarabine | Small molecule | — | Intravenous |
| Subject | Mitoxantrone | Small molecule | — | Intravenous |
| Subject | amifostine | Unknown | — | Intravenous |