drugset / Trial / NCT00002805
Combination Chemotherapy in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome
NaSingle-groupOpen-labelTreatment
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells. PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy in treating patients with acute myeloid leukemia or myelodysplastic syndrome in first relapse or who did not achieve first remission.
Timeline
- Start
- 1997-08
- Primary completion
- 2001-05
- Completion
- 2008-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cladribine | Small molecule | — | — |
| Subject | Cytarabine | Small molecule | — | — |
| Subject | Etoposide | Small molecule | — | — |
| Subject | Methotrexate | Small molecule | — | — |
| Subject | Mitoxantrone | Small molecule | — | — |
| Background | Hydrocortisone | Other / unclassified | — | — |
| Background | filgrastim | Protein / enzyme biologic | — | — |