drugset / Trial / NCT06816771

Evaluation of the Efficacy and Safety of Pazopanib in Combination with TGI/CIV for Recurrent or Refractory Rhabdomyosarcoma in Children or Adolescents

NCT06816771

Phase 2 Recruiting 38 enrolled Shandong Cancer Hospital and Institute
NaSingle-groupOpen-labelTreatment

Summary

To evaluate the efficacy and safety of pazopanib combined with TGI/CIV chemotherapy in children and adolescents with recurrent or refractory rhabdomyosarcoma.

Timeline

Start
2025-02
Primary completion
2025-12-31
Completion
2026-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Cyclophosphamide Other / unclassified
Subject Gemcitabine Small molecule
Subject Ifosfamide Small molecule
Subject Irinotecan Small molecule
Subject Paclitaxel Small molecule
Subject Pazopanib Small molecule Oral
Subject Vinorelbine Small molecule

Indications