drugset / Trial / NCT06816771

Evaluation of the Efficacy and Safety of Pazopanib in Combination with TGI/CIV for Recurrent or Refractory Rhabdomyosarcoma in Children or Adolescents

NCT06816771 ↗

Phase 2 Recruiting 38 enrolled Shandong Cancer Hospital and Institute
NaSingle-groupOpen-labelTreatment

Summary

To evaluate the efficacy and safety of pazopanib combined with TGI/CIV chemotherapy in children and adolescents with recurrent or refractory rhabdomyosarcoma.

Timeline

Start
2025-02
Primary completion
2025-12-31
Completion
2026-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Cyclophosphamide Other / unclassified — —
Subject Gemcitabine Small molecule — —
Subject Ifosfamide Small molecule — —
Subject Irinotecan Small molecule — —
Subject Nab-paclitaxel Small molecule — —
Subject Pazopanib Small molecule — Oral
Subject Vinorelbine Small molecule — —

Indications