drugset / Trial / NCT00002604
O(6)-Benzylguanine and Carmustine in Treating Patients With Solid Tumors
Phase 1
Completed
28 enrolled
Case Comprehensive Cancer Center
National Cancer Institute (NCI) · collab
NaSingle-groupOpen-labelTreatment
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. PURPOSE: Phase I trial to study the effectiveness of O(6)-benzylguanine and carmustine in treating patients who have solid tumors.
Timeline
- Start
- 1996-01
- Primary completion
- 2000-07
- Completion
- 2004-02
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | O6-benzylguanine | Small molecule | — | Intravenous |
| Subject | carmustine | Small molecule | — | Intravenous |