drugset / Trial / NCT00002759
Irinotecan Plus Cyclosporine and Phenobarbital in Treating Patients With Solid Tumors or Lymphoma
NaSingle-groupOpen-labelTreatment
Summary
Phase I trial to study the effectiveness of irinotecan plus cyclosporine and phenobarbital in treating patients who have solid tumors or lymphoma that is refractory to standard therapy. Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Cyclosporine and phenobarbital may enhance the effectiveness of irinotecan.
Timeline
- Start
- 1996-06
- Primary completion
- 2002-04
- Completion
- —
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cyclosporine | Peptide | — | Intravenous |
| Subject | Irinotecan | Small molecule | — | Intravenous |
| Subject | Phenobarbital | Unknown | — | Oral |