drugset / Trial / NCT00002771

Chemotherapy, Interferon, and Bone Marrow Transplantation in Treating Patients With Chronic Myelogenous Leukemia

NCT00002771

Phase 3 Unknown 750 enrolled German CML Study Group
RandomizedTreatment

Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining chemotherapy with bone marrow transplantation may allow the doctor to give higher doses of chemotherapy drugs and kill more cancer cells. PURPOSE: Randomized phase III trial to compare the effectiveness of various combination chemotherapy regimens or bone marrow transplantation in treating patients with chronic myelogenous leukemia.

Timeline

Start
1995-01
Primary completion
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject Busulfan Small molecule
Subject Cytarabine Small molecule Subcutaneous
Subject Hydroxyurea Other / unclassified Oral
Subject Idarubicin Small molecule Intravenous
Subject interferon alfa Protein / enzyme biologic Subcutaneous

Indications