drugset / Trial / NCT00002801

Combination Chemotherapy and Radiation Therapy in Treating Patients With Colorectal Cancer

NCT00002801

Phase 1 Completed 30 enrolled Memorial Sloan Kettering Cancer Center
Treatment

Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug and combining radiation therapy with chemotherapy may kill more tumor cells. PURPOSE: Phase I trial to study the effectiveness of combination chemotherapy consisting of fluorouracil-uracil and leucovorin plus radiation therapy in treating patients with colorectal cancer who have undergone surgery to remove the tumor.

Timeline

Start
1996-04
Primary completion
2003-12
Completion
2009-12

Drugs

EvaluationDrugModalityDoseRoute
Subject tegafur-uracil Small molecule Oral
Background Leucovorin Small molecule Oral

Indications