tegafur-uracil
Trials 13
Evidence & citations 7 cited values
Every value below carries the sentence it was read from. 20 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | TEGAFUR URACIL | “Maintenance chemotherapy should use one of the regimens: S1 (40mg, twice a day for 14 days, every 3 weeks), capecitabine (1000mg/m\^2, twice a day for 14 days, every 3 weeks)...” NCT02944708 ↗20“The SACURA trial is a randomised-controlled study evaluating the superiority of 1-year adjuvant treatment with oral tegafur-uracil (UFT) to surgery alone for stage II colon cancer.” PMID 29677641 ↗ Apr 2018 “Tegafur/uracil treatment of mice with RENCA tumors has been shown to inhibit angiogenesis, leading to a significant prolongation of life span.” NCT00855881 ↗ “Xeloda or UFT (Tegafur-uracil) With Folinic Acid in Advanced or Metastatic Colorectal Cancer” NCT00905047 ↗ “Xeloda or UFT (Tegafur-uracil) With Folinic Acid in Advanced or Metastatic Colorectal Cancer” NCT00905047 ↗ “oral Tegafur-uracil” NCT02363400 ↗ |
| Known as | fluorouracil-uracil | “This is a dose-escalation study of fluorouracil-uracil (UFT).” NCT00002801 ↗ |
| Known as | UFT | “Uracil-tegafur (UFT), an oral fluoropyrimidine prodrug, is available commercially in Japan and in several other countries.” NCT00855881 ↗7“Xeloda or UFT (Tegafur-uracil) With Folinic Acid in Advanced or Metastatic Colorectal Cancer” NCT00905047 ↗ “Patients receive oral tegafur-uracil (UFT) once daily on days 1-21.” NCT00336947 ↗ “This is a dose-escalation study of fluorouracil-uracil (UFT).” NCT00002801 ↗ “metronomic tegafur-uracil (UFT)” NCT01262274 ↗ “Why Tegafur-uracil (UFT)?” NCT01539018 ↗ “Tegafur-uracil (UFT)” NCT00385970 ↗ |
| Known as | Uracil-tegafur | “Uracil-tegafur (UFT), an oral fluoropyrimidine prodrug, is available commercially in Japan and in several other countries.” NCT00855881 ↗ |
| Action | Inhibit | “The 5-FU metabolite FdUMP binds and inhibits the enzymatic activity of thymidylate synthase (TS)” NCT00855881 ↗ |
| Modality | Small molecule | “an oral fluoropyrimidine prodrug” NCT00855881 ↗ |
| Route | Oral | “patients receive oral UFT and oral leucovorin calcium (CF) 3 times a day on days 1-28.” NCT00002801 ↗ |