Maintenance Tegafur-uracil Versus Observation Following Adjuvant Oxaliplatin-based Regimen in Patients With Stage III Colon Cancer After Radical Resection

Summary

Primary Objective: To compare 3-year disease free survival (DFS) of tegafur-uracil following adjuvant oxaliplatin-based regimen to observation following adjuvant oxaliplatin-based regimen in patients with stage III colon cancer after radical resection. Secondary Objectives: * To assess 5-year overall survival (OS) in each arm * To assess the safety profiles

Timeline

Start

2016-03

Primary completion

2017-03

Completion

2024-02-29

Publications

• Yeh YS, Tsai HL, Huang CW, Wei PL, Sung YC, Tang HC, Wang JY. Maintenance tegafur-uracil versus observation following an adjuvant oxaliplatin-based regimen in patients with stage III colon cancer after radical resection: study protocol for a randomized controlled trial. Trials. 2017 Apr 26;18(1):191. doi: 10.1186/s13063-017-1904-9.

Drugs

Indications