drugset / Trial / NCT02447679

Oral Thalidomide and Tegafur-uracil to Decrease Hepatocellular Carcinoma Recurrence

NCT02447679

Phase 2 Completed 40 enrolled Chang Gung Memorial Hospital
NaSingle-groupOpen-labelPrevention

Summary

This single-centered phase II clinical study is to obtain preliminary information on 1-year recurrence-free survival rate, recurrence-free survival and safety profile of thalidomide in combination with tegafur-uracil in hepatocellular carcinoma after hepatectomy and explore biomarkers(VEGF/bFGF) for thalidomide response.

Timeline

Start
2010-08
Primary completion
2017-01-31
Completion
2017-02-02

Drugs

EvaluationDrugModalityDoseRoute
Subject Thalidomide Other / unclassified 400 mg Oral
Background tegafur-uracil Small molecule