drugset / Trial / NCT00002872
Bleomycin, Doxycycline, or Talc in Treating Patients With Malignant Pleural Effusions
Phase 3
Completed
480 enrolled
Eastern Cooperative Oncology Group
National Cancer Institute (NCI) · collabNorth Central Cancer Treatment Group · collab
RandomizedSupportive care
Summary
RATIONALE: Some drugs such as bleomycin or doxycycline, or other compounds like talc, may help to control fluid in the chest caused by cancer. It is not yet known if bleomycin, doxycycline, or talc is more effective in treating patients with malignant pleural effusions. PURPOSE: Randomized phase III trial to compare the effectiveness of bleomycin, doxycycline, or talc in treating patients with malignant pleural effusions.
Timeline
- Start
- 1997-01-10
- Primary completion
- 2003-02
- Completion
- —
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Bleomycin | Unknown | — | Other |
| Subject | Doxycycline | Small molecule | — | Other |
| Subject | TALC ANHYDROUS | Small molecule | — | Other |