drugset / Trial / NCT00003057
Octreotide Compared With Loperamide Hydrochloride for Chemotherapy-Related Diarrhea in Patients With Colorectal Cancer
Phase 3
Completed
500 enrolled
Eastern Cooperative Oncology Group
Cancer and Leukemia Group B · collabNational Cancer Institute (NCI) · collabSWOG Cancer Research Network · collab
RandomizedSupportive care
Summary
RATIONALE: Drugs such as octreotide and loperamide hydrochloride use different ways to relieve the diarrhea caused by chemotherapy. PURPOSE: Randomized phase III trial to compare the effectiveness of octreotide with loperamide hydrochloride for the treatment of chemotherapy-related diarrhea in patients who have colorectal cancer.
Timeline
- Start
- 1997-03-26
- Primary completion
- 2000-05
- Completion
- —
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Loperamide | Small molecule | — | Oral |
| Subject | Octreotide | Peptide | — | Subcutaneous |